Bone Morphogenetic Protein Receptor, Type IB Proteins (BMPR1B)

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. Additionally we are shipping BMPR1B Antibodies (196) and BMPR1B Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BMPR1B 12167 P36898
BMPR1B 658 O00238
Rat BMPR1B BMPR1B 310914  
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Top BMPR1B Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 21 to 31 Days
$286.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
$272.80
Details
HOST_Human Cells Mouse Fc Tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$272.80
Details
HOST_Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Log in to see 20 to 21 Days
$338.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$641.43
Details

BMPR1B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human , , , , ,
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Top referenced BMPR1B Proteins

  1. Human BMPR1B Protein expressed in HEK-293 Cells - ABIN2180585 : Lee, Kirkbride, Sheu, Blobe: The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors. in Molecular biology of the cell 2009 (PubMed)

More Proteins for Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) Interaction Partners

Zebrafish Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. These results indicate a germ-cell-autonomous role for BMP signal transduction in germ-cell differentiation.

Mouse (Murine) Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. dermal BMPRIB+ cells possessed a similar osteogenic differentiation potential with BMSCs in a mouse model. Dermal BMPRIB+ subpopulations possessed low immunogenicity and immunosuppressive properties before and after osteogenic differentiation.

  2. BMPR1B plays distinct roles from BMPR1A and ACVR1 in maintaining bone mass and transducing BMP signaling

  3. This study demonistrated that BMP signaling has no major role in the development of excitatory and inhibitory synapses in the lateral superior olive.

  4. Local administration of adenovirus expressing siRNA-targeting BMPR-IB may be a feasible and effective therapeutic candidate to treat or prevent wear debris-associated osteolysis.

  5. Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin (show CFL1 Proteins) activity

  6. the BMP-2 (show BMP2 Proteins)-BMPR-IB-ODAM (show ODAM Proteins)-MAPK (show MAPK1 Proteins) signaling cascade has important roles in ameloblast differentiation and enamel mineralization

  7. Variation in BMPR1B is associated with dizygotic twinning.

  8. signaling through BMPR1A (show BMPR1A Proteins);B performs at least two roles in early respiratory development: first, it promotes tracheal formation through repression of Sox2 (show SOX2 Proteins); and second, it restricts the site of lung bud initiation.

  9. These studies support a role for a functional BMP signaling axis as a tumor suppressor pathway in the ovary, with BMPR1A (show BMPR1A Proteins) and BMPR1B acting downstream of BMP ligands and upstream of BMP receptor (show BMPR1A Proteins) SMADs.

  10. results indicate a requirement for BMP signaling in generating the dorsalmost neuronal lineage of the telencephalon, DG granule neurons, and in the development of the stem cell niche that makes neurons in the adult hippocampus.

Human Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. BMPR1A (show BMPR1A PLURAL_@42556@) and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A (show BMPR1A PLURAL_@42556@) was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A (show BMPR1A PLURAL_@42556@).

  2. Mutations in three genes (GDF5 (show GDF5 Proteins), NPR2 (show NPRL2 Proteins), BMPR1B) have been reported to cause different forms of acromesomelic dysplasia

  3. Data show that protein kinase (show CDK7 Proteins) LKB1 (show STK11 Proteins) physically interacts with BMP type I receptors and requires Smad7 (show SMAD7 Proteins) protein to promote downregulation of the receptor.

  4. Results show an association between age-induced depletion of the ovarian reserve and BMPR1B receptor density and suggest that the dysregulation of BMP receptor (show BMPR1A Proteins) signalling may inhibit the normal steroidogenic differentiation required for maturation in older patients.

  5. Low expression of BMPRIB is associated with breast cancer.

  6. Two novel mutations in BMPR1B were identified in two patients with brachydactyly type A1.

  7. Using computational analyses with the COREX/BEST algorithm, the study uncovered an overall pattern connecting various regions of BMPR-1B ectodomain, including the four conserved residues in the protein-protein interface.

  8. Novel mutation in the BMPR1B gene (R486L) in a Polish family and further delineation of the phenotypic features of BMPR1B-related brachydactyly.

  9. Data found a hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia

  10. Disequilibrium of BMP2 (show BMP2 Proteins) levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.

Pig (Porcine) Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. These findings provide an important role of BMPRIB in the regulation of apoptosis and steroidogenesis of porcine granulosa cells.

  2. Report temporal regulation of BMPR1B mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. Polymorphisms within the BMPR1B gene are associated with reproductive performance.

BMPR1B Protein Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with BMPR1B

  • bone morphogenetic protein receptor, type IB (BMPR1B)
  • bone morphogenetic protein receptor, type 1B (bmpr1b)
  • bone morphogenetic protein receptor, type 1bb (bmpr1bb)
  • bone morphogenetic protein receptor, type IB (LOC100218713)
  • bone morphogenetic protein receptor, type 1B (Bmpr1b)
  • bone morphogenetic protein receptor, type 1ba (bmpr1ba)
  • bone morphogenetic protein receptor, type IB (Bmpr1b)
  • Acvrlk6 protein
  • AI385617 protein
  • ALK-6 protein
  • Alk6 protein
  • alk6b protein
  • alk6tr protein
  • AV355320 protein
  • BMP15 protein
  • BMPR-1B protein
  • BMPR-IB protein
  • bmpr1b protein
  • BMPRIB protein
  • BR1b protein
  • CDw293 protein
  • CFK-43a protein
  • FecB protein
  • RPK-1 protein
  • SKR6 protein
  • zALK-6 protein
  • zgc:92220 protein
  • zgc:172219 protein

Protein level used designations for BMPR1B

BMP receptor IB , activin receptor-like kinase 6 , bone morphogenetic protein receptor type-1B , bone morphogenetic protein receptor, type IB , bone morphogenetic protein receptor type IB,b , bone morphogenetic protein receptor type-1B-like , BMP type-1B receptor , serine/threonine-protein kinase receptor R6 , alk6 , bone morphogenetic protein receptor, type 1b , BMPR-1B , serine/threonine receptor kinase , bone morphogenetic protein receptor IB , bone morphogenetic protein binding serine/threonine kinase receptor , ALK-6 , SKR6 , receptor protein kinase , bone morphogenetic protein receptor 1B

GENE ID SPECIES
443454 Ovis aries
780089 Xenopus (Silurana) tropicalis
100149664 Danio rerio
461683 Pan troglodytes
705474 Macaca mulatta
100218713 Taeniopygia guttata
100397724 Callithrix jacchus
100444576 Pongo abelii
100467049 Ailuropoda melanoleuca
12167 Mus musculus
30742 Danio rerio
658 Homo sapiens
478484 Canis lupus familiaris
407128 Bos taurus
310914 Rattus norvegicus
396030 Gallus gallus
396691 Sus scrofa
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