BMPR1B Protein (Fc Tag,His tag)

Catalog No. ABIN7535009

Product Details

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BMPR1B protein is labelled with Fc Tag,His tag.

Purpose: Active Recombinant Human BMPR-1B/ALK-6/CDw293 Protein

Sequence: KKEDGESTAP TPRPKVLRCK CHHHCPEDSV NNICSTDGYC FTMIEEDDSG LPVVTSGCLG LEGSDFQCRD TPIPHQRRSI ECCTERNECN KDLHPTLPPL KNRDFVDGPI HHR

Specificity: Lys14-Arg126

Purity: > 90 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: 1.Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 4 μg/mL (100 μL/well) can bind Human BMPRIB with a linear range of 20-338 ng/mL.|2.Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED₅₀ for this effect is 0.6-2.3 μg/mL in the presence of 30 ng/mL of rhBMP-4.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Alternative Name: BMPR-1B/ALK-6/CDw293 (BMPR1B Products)

Synonyms: ALK6 Protein, BMPR-IB Protein, FecB Protein, alk-6 Protein, alk6 Protein, cdw293 Protein, alk6b Protein, zgc:172219 Protein, BMPR1B Protein, AI385617 Protein, ALK-6 Protein, AV355320 Protein, Acvrlk6 Protein, Alk6 Protein, BMPR-1B Protein, CFK-43a Protein, SKR6 Protein, BR1b Protein, alk6tr Protein, bmpr1b Protein, zALK-6 Protein, zgc:92220 Protein, CDw293 Protein, BMP15 Protein, BMPRIB Protein, RPK-1 Protein, bone morphogenetic protein receptor type 1B Protein, bone morphogenetic protein receptor, type IBb Protein, bone morphogenetic protein receptor, type 1B Protein, bone morphogenetic protein receptor, type IBa Protein, BMPR1B Protein, bmpr1b Protein, bmpr1bb Protein, Bmpr1b Protein, bmpr1ba Protein

Background: ALK-6,ALK6,AMDD,BDA1D,BDA2,CDw293,BMPR1B, ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, bone morphogenetic protein receptor type-1B

Gene ID: 658

UniProt: O00238