CD320 Molecule Proteins (CD320)

CD320 encodes the transcobalamin receptor that is expressed at the cell surface. Additionally we are shipping CD320 Antibodies (37) and CD320 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD320 54219 Q9Z1P5
CD320 51293 Q9NPF0
CD320 362851 Q5HZW5
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Top CD320 Proteins at

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Escherichia coli (E. coli) Human GST tag CD320 Molecule (CD320) (AA 36-231), (partial) protein (GST tag) 50 μg Log in to see 13 to 16 Days
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 20 to 21 Days
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Human Rat Fc Tag SDS-PAGE 200 μg Log in to see 20 to 21 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

CD320 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Human , , , , ,
, , ,
Rat (Rattus) ,

More Proteins for CD320 Molecule (CD320) Interaction Partners

Mouse (Murine) CD320 Molecule (CD320) interaction partners

  1. CD320 role in the hippocampal long-term potentiation and the hippocampal pyramidal neurons.

  2. Severe cobalamin depletion in the central nervous system (CNS) after birth in TCblR knockouts indicates that TCblR is the only receptor responsible for cobalamin uptake in the CNS

  3. In vivo, endogenous PCSK9 (show PCSK9 Proteins) regulates VLDLR (show VLDLR Proteins) protein levels and triglyceride accumulation in adipose tissue.

  4. Diabetic rats showed severe hyperlipidemia on d 21 and 28, with a dramatic decline in VLDL-R (show VLDLR Proteins) protein in skeletal muscle (>90%), heart (approximately 50%) and a loss of adipose tissues itself.

  5. Reelin (show RELN Proteins) binds several receptors, including the VLDL receptor (show VLDLR Proteins) in cultured hippocampus neurons.

  6. VLDL and LDL lowering by gene transfer of the VLDL receptor (show VLDLR Proteins) combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor (show LDLR Proteins)-deficient mice

  7. These data demonstrate a cell-autonomous function of ApoER2 (show LRP8 Proteins), and most likely VLDLR (show VLDLR Proteins) and Dab1 (show DAB1 Proteins), in postnatal migration of neuroblasts in the forebrain, which is suggested to depend on ligands other than Reelin (show RELN Proteins).

  8. The high affinity of apoE4 to the LDLR (show LDLR Proteins) enhances VLDL sequestration on the hepatocyte surface but delays their internalization.

  9. Data show that thrombospondin-1 (THBS-1 (show THBS1 Proteins)) is a novel physiological ligand for ApoER2 (show LRP8 Proteins) and VLDLR (show VLDLR Proteins), and that lack of THBS-1 (show THBS1 Proteins) results in anatomical abnormalities of the RMS and leads to a reduction of postnatal neuronal precursors entering the OB.

Human CD320 Molecule (CD320) interaction partners

  1. Although not significant when corrected for multiple testing, eight single nucleotide polymorphisms (SNPs) in two genes, transcobalamin II (TCN2 (show TCN2 Proteins)) and the transcobalamin II (show TCN2 Proteins)-receptor (TCblR), were found to influence several clinical traits of cobalamin deficiency.

  2. The soluble transcobalamin receptor is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta.

  3. Transcobalamin II (TCN2 (show TCN2 Proteins) 67A>G and TCN2 (show TCN2 Proteins) 776C>G) and transcobalamin II (show TCN2 Proteins) receptor (TCblR 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion

  4. Data indicate that only the extracellular region (aa 32-229) of TCblR/CD320 is needed for transcobalamin-cobalamin (TC-Cbl (show CBL Proteins)) binding.

  5. Proliferating cancer cells express measurable levels of TCII (show TCN2 Proteins) and TCII (show TCN2 Proteins)-R.

  6. TCblr SNP were associated with omphalocele suggests that disruption of methylation reactions, in which folate, vitamin B12 (show NDUFB3 Proteins), and homocysteine play critical parts, may be a risk factor for omphalocele.

  7. Our data suggest that variation in TCblR plays a role in neural tube defect risk and that these variants may modulate cobalamin metabolism.

  8. the cell cycle associated expression of TCblR appears to be tightly regulated in synchrony with the proliferative phase of the cell cycle.

  9. Analysis of TCblR/CD320, the gene for the receptor for cellular uptake of transcobalamin-bound cobalamin, identified a homozygous single codon deletion, c.262_264GAG (p.E88del), resulting in the loss of a glutamic acid residue.

  10. Confocal microscopy of tonsil sections revealed co-localization of CD320 with CD19 (show CD19 Proteins) and CD38 but not with CD3 (show CD3 Proteins) indicating that germinal center B cells expressed CD320 in addition to follicular dendritic cells.

CD320 Protein Profile

Protein Summary

This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD320 Molecule Proteins (CD320)

  • CD320 molecule (CD320)
  • CD320 antigen (Cd320)
  • CD320 molecule (Cd320)
  • 8D6 protein
  • 8D6A protein
  • 425O18-1 protein
  • D17Ertd716e protein
  • NG29 protein
  • RGD1305860 protein
  • TCblR protein
  • VLDL protein

Protein level used designations for CD320 Molecule Proteins (CD320)

CD320 molecule , TCblR , putative VLDL lipoprotein receptor , transcobalamin receptor , 8D6 antigen , CD320 antigen , FDC-SM-8D6 , FDC-signaling molecule 8D6

456436 Pan troglodytes
476721 Canis lupus familiaris
54219 Mus musculus
51293 Homo sapiens
362851 Rattus norvegicus
505043 Bos taurus
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