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anti-Centromere Protein E, 312kDa (CENPE) Antibodies

Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Additionally we are shipping CENPE Kits (34) and CENPE Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CENPE 362044  
CENPE 229841 Q6RT24
CENPE 1062 Q02224
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Top anti-CENPE Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, FACS, IF, IP, WB 50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Mouse Un-conjugated ICC, IF, IP, WB 50 μL Log in to see 8 to 10 Days
$573.83
Details
Human Rabbit Un-conjugated WB CENPE Antibody (C-term)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CENPE antibody detected the CENPE protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, IP, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Mouse Un-conjugated IP, WB 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$345.40
Details

CENPE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,
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Mouse (Murine) , ,
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Human , , , ,
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Top referenced anti-CENPE Antibodies

  1. Human Monoclonal CENPE Primary Antibody for ICC, FACS - ABIN108563 : Yen, Compton, Wise, Zinkowski, Brinkley, Earnshaw, Cleveland: CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. in The EMBO journal 1991 (PubMed)
    Show all 10 references for ABIN108563

More Antibodies against CENPE Interaction Partners

Mouse (Murine) Centromere Protein E, 312kDa (CENPE) interaction partners

  1. Exacerbating chromosome missegregation in CENP-E+/- mice by reducing levels of another mitotic checkpoint component (show BUB3 Antibodies), Mad2 (show MXI1 Antibodies), results in elevated cell death and decreased tumor formation compared with reduction of either protein alone.

  2. CENP-E stabilises BubR1 (show BUB1B Antibodies), thereby impacting meiosis I progression, and mediates bi-orientation by promoting kinetochore reorientation and preventing chromosomal drift towards the poles.

  3. results suggest that CENP-E is implicated in the spindle checkpoint, and in chromosome alignment, during the two meiotic divisions in vertebrate males

  4. Deletion of the mouse gene CENP-E causes unstable kinetochore-microtubule capture and chromosomal instability. (CENP-E)

  5. Shugoshin 2 (show SGOL2 Antibodies) is necessary for the loading of MCAK (show KIF2C Antibodies) at the inner centromere, but is dispensable for the loading of the outer kinetochore proteins BubR1 (show BUB1B Antibodies) and CENP-E.

Human Centromere Protein E, 312kDa (CENPE) interaction partners

  1. CTCF (show CTCF Antibodies) helps recruit CENP-E to the centromere during mitosis and that it may do so through a structure stabilized by the CTCF (show CTCF Antibodies)/CENP-E complex.

  2. Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.

  3. CENP-Q (show CENPQ Antibodies) - a subunit of the CENP-O (show CENPO Antibodies) complex (comprising CENP-O (show CENPO Antibodies), CENP-P (show CENPP Antibodies), CENP-Q (show CENPQ Antibodies) and CENP-U (show MLF1IP Antibodies)) that targets polo-like kinase (Plk1 (show PLK1 Antibodies)) to kinetochores - is also required for the recruitment of CENP-E to kinetochores.

  4. CENP-E-driven chromosome congression is guided by microtubule detyrosination.

  5. CENP-E expression is highest in basal-like subtype among breast cancer patients.

  6. An unexpected role of CENP-E elongated stalk in ensuring stability of kinetochore-microtubule attachments during chromosome congression and segregation.

  7. dynein and CENP-E at kinetochores drive congression of peripheral polar chromosomes by preventing arm-ejection forces mediated by chromokinesins from working in the wrong direction.

  8. Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism.

  9. A CENP-E mediated wall-tethering event and a MCAK (show KIF2C Antibodies)-mediated wall-removing event show that human chromosome-microtubule attachment is achieved through a set of deterministic sequential events rather than stochastic direct capture of microtubule ends.

  10. The changes in ATP binding affinity and conformational deviations in human CENP-E motor domain, were studied.

CENPE Antigen Profile

Protein Summary

Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.

Gene names and symbols associated with CENPE

  • centromere protein E, 312kDa (CENPE) antibody
  • centromere protein E, 312kDa (cenpe) antibody
  • centromere protein E (Cenpe) antibody
  • 312kDa antibody
  • AU019344 antibody
  • BC049989 antibody
  • C530022J18 antibody
  • CENP-E antibody
  • CENPE antibody
  • KIF10 antibody
  • PPP1R61 antibody
  • XCENP-E antibody

Protein level used designations for CENPE

centromere protein E, 312kDa , centromere protein E - 312kD , centromere-associated protein E , N-7 kinesin , centromere autoantigen E , centromeric protein E , kinesin 10 , kinesin superfamily protein 10 , motor domain of KIF10 , Centromere autoantigen E (312kD) , kinesin family member 10 , kinesin-related protein CENPE , protein phosphatase 1, regulatory subunit 61

GENE ID SPECIES
281681 Bos taurus
422716 Gallus gallus
461413 Pan troglodytes
610125 Canis lupus familiaris
100013897 Monodelphis domestica
100068227 Equus caballus
100126678 Xenopus (Silurana) tropicalis
362044 Rattus norvegicus
229841 Mus musculus
1062 Homo sapiens
100343917 Oryctolagus cuniculus
Selected quality suppliers for anti-CENPE (CENPE) Antibodies
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