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Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (CHI3L1)

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies (67) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHI3L1 12654 Q61362
CHI3L1 1116 P36222
CHI3L1 89824 Q9WTV1
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Top Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_CHO Human His tag 10 μg Log in to see 7 to 8 Days
$170.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Yeast REACT_Buffalo His tag   1 mg Log in to see 56 to 66 Days
$2,986.50
Details

CHI3L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , , , ,
, ,
Rat (Rattus)

Top referenced Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins

  1. Mouse (Murine) CHI3L1 Protein expressed in Human Cells - ABIN2008418 : Nishikawa, Millis: gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells. in Experimental cell research 2003 (PubMed)
    Show all 3 references for ABIN2008418

  2. Human CHI3L1 Protein expressed in Human Cells - ABIN2004130 : Recklies, Ling, White, Bernier: Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for ABIN2004130

  3. Human CHI3L1 Protein expressed in CHO - ABIN1098537 : Bonneh-Barkay, Bissel, Wang, Fish, Nicholl, Darko, Medina-Flores, Murphey-Corb, Rajakumar, Nyaundi, Mellors, Bowser, Wiley: YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. in The American journal of pathology 2008 (PubMed)
    Show all 2 references for ABIN1098537

More Proteins for Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Interaction Partners

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. IL-18 (show IL18 Proteins) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Proteins)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  2. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  3. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  4. Results do not support a role of BRP (show GDF5 Proteins)-39 in the pathogenesis of experimental autoimmune encephalitis.

  5. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

  6. mechanism of BRP (show GDF5 Proteins)-39 in bleomycin-induced pulmonary fibrosis

  7. Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis

  8. Data show that IL-1 (show IL1A Proteins)-induced transcriptin factor RelB (show RELB Proteins)/NF-kappa B p50 (show NFKB1 Proteins) Subunit complex formation was further promoted by oncostatin M (show OSM Proteins) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.

  9. These results indicate that catalytically inactive BRP (show GDF5 Proteins)-39 and Ym1 (show CHI3L3 Proteins) are constitutive genes in normal mouse lung.

  10. BRP (show GDF5 Proteins)-39 is involved in repressing the M1 proinflammatory phenotype in hyperoxia, thereby deactivating inflammatory responses in macrophages and preventing neonatal lung injury.

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. This review comprehensively analyzes recent data about expression pattern, and involvement of human YKL-40, YKL-39 (show CHI3L2 Proteins) and SI-CLP (show CHID1 Proteins) in cancer. [review]

  2. Increased mRNA level of CHI3L1 could be associated with the progression of astrocytoma and poor patient survival not only for glioblastoma, but for lower grade astrocytoma tumors as well.

  3. serum YKL-40 level in coronary artery disease patients was significantly higher than that in control subjects.

  4. Study suggests that a newly identified subgroup of SSEA (show MPST Proteins)-4 and YKL-40 positive cells constitute a fraction of astroglial progenitors, and suggests the name SYPAP (SSEA (show MPST Proteins)-4 and YKL-40 positive astroglial progenitors) for this particular population

  5. Serum YKL-40 level increases with severity of obstructive sleep apnea syndrome (OSAS). The findings suggest that YKL-40 may be a useful biomarker for inflammation in patients with OSAS.

  6. CHI3L1 is expressed during the process of differentiation and maturation of dendritic cells in time dependent manner, it could play a crucial role in the dendritic cells immune response.

  7. Neurogranin (show NRGN Proteins) and YKL-40 are promising AD biomarkers, independent of and complementary to the established core Alzheimer's disease (AD) biomarkers, reflecting additional pathological changes in the course of AD

  8. Data show that the expression of chitinase 3-like 1 (cartilage glycoprotein-39) protein (CHI3L1) was higher in cancerous tissues than in normal tissues.

  9. The serum YKL-40 cutoff to identify beta-thalassemia major patients with liver cirrhosis or heart disease was determined.

  10. We identified five new biomarkers: GDF15 (show GDF15 Proteins), osteonectin (show SPARC Proteins), TRAP5, TWEAK (show TNFSF12 Proteins), and YKL40 as being promising markers for monitoring bone metastases.

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Protein Profile

Protein Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Gene names and symbols associated with CHI3L1

  • chitinase 3-like 1 (Chi3l1)
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1)
  • chitinase 3-like 1 (cartilage glycoprotein-39) (Chi3l1)
  • ASRT7 protein
  • AW208766 protein
  • BP40 protein
  • Brp39 protein
  • CGP-39 protein
  • Chil1 protein
  • CLP-1 protein
  • GP-39 protein
  • GP38K protein
  • GP39 protein
  • HC-gp39 protein
  • HCGP-3P protein
  • hCGP-39 protein
  • MGP-40 protein
  • SPC-40 protein
  • SPS-40 protein
  • YKL-40 protein
  • YKL40 protein
  • YYL-40 protein

Protein level used designations for CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPECIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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