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anti-Claudin 6 (CLDN6) Antibodies

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping Claudin 6 Kits (29) and Claudin 6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLDN6 9074 P56747
CLDN6 54419 Q9Z262
CLDN6 287098  
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Top anti-Claudin 6 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB CLDN6 Antibody (Center) western blot analysis in mouse heart tissue lysates (35µg/lane).This demonstrates the CLDN6 antibody detected the CLDN6 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB CLDN6 Antibody (Center) (ABIN654669) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the CLDN6 antibody detected the CLDN6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from RAW264.7 cells treated with UV 5', using Claudin 6 (Phospho-Tyr219) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human HOST_Rat (Rattus) Un-conjugated cELISA, FACS BOSC23 cells were transiently transfected with an expression vector encoding either Claudin 6 (red curve) or an irrelevant protein (control transfectant). Binding of WU-9E1 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with Claudin 6 transfected cells. CGE analysis of purified WU-9E1 monoclonal antibody. Lane 1: molecular weight marker, Lane 2: 2 μg of WU-9E1 antibody. Proteins were separated by CGE (capillary gel electrophoresis, Agilent 2100 Bioanalyzer). Internal control bands (240 kDa / 7 kDa / 4,5 kDa). 100 μg Log in to see 5 to 6 Days
$358.05
Details
Human Rabbit Un-conjugated WB Anti-Claudin 6 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Claudin 6 staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Claudin 6 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using CLDN6 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using CLDN6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

CLDN6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Claudin 6 Antibodies

  1. Human Monoclonal CLDN6 Primary Antibody for cELISA, FACS - ABIN1720916 : Loeb: The Mechanism of Diffusion of Electrolytes Through Animal Membranes. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 6 references for ABIN1720916

  2. Human Polyclonal CLDN6 Primary Antibody for EIA, WB - ABIN951551 : Wu, Liu, Ren, Xu, Yu, Li, Quan: Tight junction protein, claudin-6, downregulates the malignant phenotype of breast carcinoma. in European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2010 (PubMed)
    Show all 5 references for ABIN951551

More Antibodies against Claudin 6 Interaction Partners

Xenopus laevis Claudin 6 (CLDN6) interaction partners

  1. claudin-6 is expressed in the developing pronephric tubule and duct but not glomus. Knockdown of claudin-6 by specific morpholino led to severe defects in pronephros tubular morphogenesis and blocked the terminal differentiation of the tubule cells.

Human Claudin 6 (CLDN6) interaction partners

  1. Data show that claudin-6 (CLDN6) R209Q and occludin (OCLN (show OCLN Antibodies)) P24A mutations do not affect HCV pseudoparticles (HCVpp) entry.

  2. The expression of ASK1 (show MAP3K5 Antibodies) is correlated with the level of claudin-6 in cervical carcinoma cells and tissues.

  3. High levels of CLDN6 are associated with non-small-cell lung cancer.

  4. The expression of claudin-6 was down regulated in gastric cancer tissue.

  5. Only some hepatitis C virus strains efficiently use CLDN6 for infection.

  6. This work provides a proof of concept for the use of Claudin-6 to eliminate residual undifferentiated human pluripotent stem cells from culture.

  7. Although claudin-6 and claudin-9 (show CLDN9 Antibodies) can serve as entry factors in cell lines, hepatitis C virus infection into human hepatocytes is not dependent on claudin-6 and claudin-9 (show CLDN9 Antibodies).

  8. ASK1 (show MAP3K5 Antibodies) signal may play a positive role in the inhibitory effect of claudin-6 in breast cancer.

  9. Our results show that claudin-6 protein is significantly down-regulated in breast invasive ductal carcinomas

  10. CLDN6 is not a specific biomarker for atypical teratoid rhabdoid tumors as it is expressed in a variety of other pediatric CNS and soft tissue tumors.

Mouse (Murine) Claudin 6 (CLDN6) interaction partners

  1. Cldn6 is expressed by pulmonary epithelium during lung organogenesis.

  2. The Inv (show INVS Antibodies)-Cldn6-CDelta206 transgenic mice displayed a developmental delay in epidermal permeability barrier formation, as shown by the expression of keratins and Cldns, and by X-Gal (show GAL Antibodies) penetration assays.

  3. the normally robust injury response mechanism of the epidermis is lost in the aging Involucrin (show IVL Antibodies)-Cldn6-CDelta196 transgenic epidermis

  4. Permeability barrier dysfunction in transgenic mice overexpressing claudin 6.

  5. Cldn6 plays a role in the differentiation processes of the epidermis and hair follicle

  6. Claudin-6 mRNA was found to be differentially expressed in four different adipose tissues, and up-regulated in each fat depot of mice fed a high-fat diet. Levels of claudin-6 transcripts were increased during differentiation of 3T3-L1 ce

  7. developmentally expressed claudin isoforms include claudin 6, claudin 9 (show CLDN9 Antibodies), and claudin 13 (show CLDN13 Antibodies)

  8. Results demonstrate that the overexpression of a tail truncation mutant of claudin 6 (Cldn6) mislocalizes Cldn6 and other Cldn proteins to the cytoplasm and triggers a postnatal increase in proliferation and aberrant differentiation of the epidermis.

  9. Tight junctions containing claudin 6 are essential for blastocyst formation in preimplantation mouse embryos

  10. Expression analysis in mice has shown that Claudin-6 is one of the few genes that allows for the targeting of the definitive endoderm throughout the entire anterior-posterior axis, before and after gut (show GUSB Antibodies) tube patterning.

Claudin 6 (CLDN6) Antigen Profile

Protein Summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Gene names and symbols associated with anti-Claudin 6 (CLDN6) Antibodies

  • claudin 6, gene 1 (cldn6.1) antibody
  • claudin 6 (CLDN6) antibody
  • claudin 6 (Cldn6) antibody
  • AL024037 antibody
  • cldn4l2 antibody
  • CLDN6 antibody

Protein level used designations for anti-Claudin 6 (CLDN6) Antibodies

claudin 6 , claudin-6 , skullin , tight junction molecule claudin 6

GENE ID SPECIES
446591 Xenopus laevis
467882 Pan troglodytes
9074 Homo sapiens
54419 Mus musculus
490048 Canis lupus familiaris
511318 Bos taurus
287098 Rattus norvegicus
100302020 Sus scrofa
100735319 Cavia porcellus
101117294 Ovis aries
Selected quality suppliers for anti-Claudin 6 (CLDN6) Antibodies
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