Claudin 6 antibody (pTyr219)

Catalog No. ABIN7138959

Product Details anti-Claudin 6 Antibody

Target: Claudin 6 (CLDN6)

Binding Specificity: pTyr219

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 219 (T-K-N-Y(p)-V) derived from Human Claudin 6.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 6

Target: Claudin 6 (CLDN6)

Alternative Name: CLDN6 (CLDN6 Products)

Synonyms: cldn4l2 antibody, cldn6 antibody, CLDN6 antibody, AL024037 antibody, claudin 6, gene 1 L homeolog antibody, claudin 6 antibody, cldn6.1.L antibody, CLDN6 antibody, Cldn6 antibody

Background:

Background:

Claudin 6 Plays a major role in tight junction-specific obliteration of the intercellular space. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO- 3.

Keen T.J., Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Troy T., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Clark H.F., Genome Res. 13:2265-2270(2003).

Aliases: Claudin-6 antibody, Claudin6 antibody, CLD6_HUMAN antibody, CLDN 6 antibody, CLDN6 antibody, OTTHUMP00000159248 antibody, Skullin 2 antibody, Skullin antibody, UNQ757/PRO1488 antibody

UniProt: P56747

Pathways: Hepatitis C