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Coatomer Protein Complex, Subunit alpha Proteins (COPA)

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Additionally we are shipping COPA Antibodies (19) and COPA Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat COPA COPA 304978  
COPA 12847 Q8CIE6
COPA 1314 P53621
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Top COPA Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

COPA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Coatomer Protein Complex, Subunit alpha (COPA) Interaction Partners

Mouse (Murine) Coatomer Protein Complex, Subunit alpha (COPA) interaction partners

  1. The novel function of Copa in inter-compartmental trafficking of RNA.

  2. SMN directly binds to COPI and moves with survival motor neuron within axons.

  3. In a a large-scale functional screening of mesothelioma cells, the COPA protein was highly expressed in some mesothelioma cell lines but not in a pleural mesothelial cell line.

Human Coatomer Protein Complex, Subunit alpha (COPA) interaction partners

  1. Serum xenin levels of obese patients were higher than in control groups.

  2. COPA variants impair binding to proteins targeted for retrograde Golgi-to-ER transport.

  3. Compared with day workers within the same BMI range, night workers presented a disrupted control of ghrelin (show GHRL Proteins) and xenin, associated with behavioural changes in diet and sleep and increased adiposity and related metabolic alterations.

  4. The cell membrane gene SLC4A4 (show SLC4A4 Proteins) and the trafficking regulator gene COPA, which also plays an important role in early endosome maturation, were identified for the cellular entry of poly-arginine peptide.

  5. Results show that the interaction between SMN (show STMN1 Proteins) and alpha-COP serves an important function in the growth and maintenance of motor neuron processes and may play a significant role in the pathogenesis of Spinal muscular atrophy.

  6. Electron tomography reveals Rab6 is essential to the trafficking of trans-Golgi clathrin and COPI-coated vesicles and the maintenance of Golgi cisternal number

  7. SMN directly binds to COPI and moves with survival motor neuron within axons.

  8. Among ten hepatocellular carcinoma cases with amplicon 1q21-q22, significant gene expression level of JTB (show JTB Proteins), SHC1 (show SHC1 Proteins), CCT3 (show CCT3 Proteins) and COPA in the tumors than the paired adjacent non-malignant liver tissues.

  9. These results suggested that Yip1A has a role in COPI-independent retrograde transport from the Golgi to the ER and regulates the membrane recruitment of Rab6.

Cow (Bovine) Coatomer Protein Complex, Subunit alpha (COPA) interaction partners

  1. a missense mutation in the coatomer (show COPE Proteins) protein complex, subunit alpha (COPA), a gene with previously no known role in pigmentation synthesis, is completely associated with Dominant Red in Holstein dairy cattle.

COPA Protein Profile

Protein Summary

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

Gene names and symbols associated with COPA

  • coatomer protein complex, subunit alpha (COPA)
  • WD40 repeat-containing protein (copA)
  • coatomer protein complex subunit alpha (cgd8_860)
  • coatomer protein complex subunit alpha (Chro.80105)
  • Coatomer subunit alpha (AFUA_3G08840)
  • coatomer protein complex, subunit alpha (copa)
  • coatomer protein complex subunit alpha (COPA)
  • coatomer protein complex subunit alpha (Copa)
  • AU040324 protein
  • cb281 protein
  • COPA protein
  • DDBDRAFT_0189693 protein
  • DDBDRAFT_0233797 protein
  • DDB_0189693 protein
  • DDB_0233797 protein
  • DKFZp469O221 protein
  • fb13c12 protein
  • HEP-COP protein
  • wu:fb13c12 protein
  • xenin protein

Protein level used designations for COPA

coatomer protein complex, subunit alpha , coatomer protein complex alpha subunit , coatomer protein complex subunit alpha , Coatomer subunit alpha , coatomer subunit alpha , alpha-COP , alpha-coat protein , HEPCOP , alpha coat protein , proxenin , xenin , sneezy , HEP-COP

GENE ID SPECIES
469552 Pan troglodytes
719683 Macaca mulatta
8616271 Dictyostelium discoideum AX4
100173345 Pongo abelii
3374641 Cryptosporidium parvum Iowa II
3415895 Cryptosporidium hominis TU502
3512069 Aspergillus fumigatus Af293
100023010 Monodelphis domestica
100158562 Xenopus (Silurana) tropicalis
100195324 Salmo salar
100379186 Bombyx mori
100596479 Nomascus leucogenys
304978 Rattus norvegicus
12847 Mus musculus
1314 Homo sapiens
260439 Danio rerio
446322 Xenopus laevis
426906 Gallus gallus
100126041 Bos taurus
478973 Canis lupus familiaris
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