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CRIM1 encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. Additionally we are shipping CRIM1 Kits (8) and CRIM1 Proteins (5) and many more products for this protein.
Showing 10 out of 36 products:
Human Monoclonal CRIM1 Primary Antibody for IHC (p), ELISA - ABIN393225
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 5 references for ABIN393225
Human Polyclonal CRIM1 Primary Antibody for IHC, IHC (p) - ABIN4300479
Nyström, Hultenby, Ek, Sjölund, Axelson, Jirström, Saleem, Nilsson, Johansson: CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009
Show all 4 references for ABIN4300479
Human Polyclonal CRIM1 Primary Antibody for IF (p), IHC (p) - ABIN676853
Zeng, Zhang, Yi, Wu, Wan, Tang: CRIM1, a newfound cancer-related player, regulates the adhesion and migration of lung cancer cells. in Growth factors (Chur, Switzerland) 2016
Human Polyclonal CRIM1 Primary Antibody for EIA, IF - ABIN1449941
Kolle, Georgas, Holmes, Little, Yamada: CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis. in Mechanisms of development 2000
these findings implicate CRIM1 in endothelial cell development and homeostasis in the coronary vasculature.
Collectively, our data demonstrates that Crim1 is essential for cell-autonomous and paracrine aspects of heart development
Crim1 regulates integrin signaling in murine lens development
CRIM1 is the causative gene for Colobomatous macrophthalmia with microcornea syndrome and is important for eye development.
Vascular endothelial cell-specific conditional compound heterozygotes for Crim1 and Vegfa (show VEGFA Antibodies) exhibit a phenotype that is more severe than each single heterozygote and indistinguishable from that of the conditional homozygotes.
Report the involvement of both endothelial cells and monocytes in the development of progressive renal fibrosis in Crim1 mutant mice.
Crim1 mutations are associated with defects in papillary development and progression to chronic kidney disease later in life.
Crim1 is required for placental development, and is necessary for the proper differentiation of sinusoidal-trophoblast giant cells and glycogen (show GYS1 Antibodies) trophoblast cells.
CRIM1 has a role in capillary formation and maintainance during angiogenesis
CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface
primary role of zebrafish crim1 is likely to be the regulation of somitic and vascular development
These observations provide evidence for the first time that CRIM1 plays a role in cancer cells by enhancing the migration and adhesion and increasing the expression of N-CAD and E-CAD.
Knock down of CRIM1 had no effect on VEGF (show VEGFA Antibodies)-induced proliferation or migration of umbilical vein endothelial cells (HUVECs), indicating that basal CRIM1 is not involved in the proliferation or migration of endothelial cells.
Data suggest that CRIM1 plays role in cancer progression/metastasis, epithelial-mesenchymal transition, and neoplastic angiogenesis. [REVIEW]
BMPs inhibitor CRIM1 is increased and correlates with higher levels of serum PIPIII showing an imbalance in favor of pro-fibrotic mechanisms in CHF.
CRIM1 is an early response gene in the presence of both angiogenic stimulation (VEGF (show VEGFA Antibodies)) and environmental (extracellular matrix) factors, and Erk (show EPHB2 Antibodies) and FAK (show PTK2 Antibodies) might be involved in the upregulation of CRIM1 mRNA expression in vascular endothelial cells.
Study demonstrated that CRIM1 is expressed at high levels in resistant leukemia cells, indicating that CRIM1 may play a role in drug-resistance.
CRIM1 has a role in capillary formation and maintenance during angiogenesis
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins.
cysteine rich transmembrane BMP regulator 1 (chordin-like)
, cysteine-rich motor neuron 1 protein
, cysteine-rich motor neuron 1
, cysteine-rich motor neuron 1 protein-like
, cysteine rich transmembrane BMP regulator 1
, cysteine-rich repeat-containing protein S52
, cysteine-rich motorneuron 1