Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Additionally we are shipping CYBB Kits (8) and CYBB Proteins (6) and many more products for this protein.
Showing 10 out of 117 products:
Mouse (Murine) Monoclonal CYBB Primary Antibody for IF, WB - ABIN968523
Jacobsen, Skalnik: YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter. in The Journal of biological chemistry 1999
Show all 4 references for ABIN968523
Human Polyclonal CYBB Primary Antibody for IF (cc), IF (p) - ABIN750688
Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase. in Vascular pharmacology 2013
Show all 4 references for ABIN750688
Human Polyclonal CYBB Primary Antibody for IHC, IHC (p) - ABIN4301440
Rajtik, Carnicka, Szobi, Giricz, O-Uchi, Hassova, Svec, Ferdinandy, Ravingerova, Adameova: Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis. in European journal of pharmacology 2016
Show all 3 references for ABIN4301440
Human Monoclonal CYBB Primary Antibody for ICC, IF - ABIN1042596
Burritt, Quinn, Jutila, Bond, Jesaitis: Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. in The Journal of biological chemistry 1995
Show all 2 references for ABIN1042596
Human Monoclonal CYBB Primary Antibody for WB - ABIN1042597
Baniulis, Burritt, Taylor, Dinauer, Heyworth, Parkos, Magnusson, Jesaitis: Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. in European journal of haematology 2005
Chicken Polyclonal CYBB Primary Antibody for IHC, WB - ABIN2781794
Fink, Duval, Martel, Soucy-Faulkner, Grandvaux: Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappaB in airway epithelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
Data indicate that NADPH oxidase (show NOX1 Antibodies) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.
The ROS (show ROS1 Antibodies) levels of the study group decreased obviously before irradiation (P<0.01), however, the radiation-induced ROS (show ROS1 Antibodies) of the study group was at a high level even when irradiation had been terminated for 2 h (P<0.01). Moreover, NOX2 and NOX4 (show NOX4 Antibodies) levels and total SOD (show SOD1 Antibodies) activity decreased (P<0.01), while the levels of SOD1 (show SOD1 Antibodies) were stably maintained (P>0.05).
The authors report the absence of an oxidative burst in the phagocytes of the patient with a novel missense c.1226C > A mutation in the CYBB gene resulting in p.A409E.
alkali burns markedly upregulated the transcription and expression of Nox2 and Nox4 (show NOX4 Antibodies) in human or mouse corneas.
These findings provide novel insights into oleanolic acid-induced inhibition of rectal cancer cell proliferation and highlight NOX2/ROS (show ROS1 Antibodies)/HIF-1alpha (show HIF1A Antibodies) axis as a novel therapeutic target for the treatment of rectal cancer.
NOX2 induces antigen release from endosomes for cross-presentation by direct oxidation of endosomal lipids.
Critical role of the Mac1 (show ITGAM Antibodies)/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration
Female patients with severe inflammatory bowel disease should be checked for X-CGD genes.
Blunting of NOX2-dependent IKKepsilon (show IKBKE Antibodies) oncogenic kinase expression reduces proliferation and viability of human breast cancer cells.
Furthermore, a direct interaction between AnkA and HDAC1 (show HDAC1 Antibodies) was detected at the CYBB promoter, and was critical for AnkA-mediated CYBB repression.
There is a mutual enhancement between HMGB1 (show HMGB1 Antibodies) and Nox2-derived reactive oxygen species in the diabetic retina.
Data indicate that the efficiency of NADPH oxidase (show NOX1 Antibodies) enzymatic activity is higher at endoplasmic reticulum (ER).
A p47(phox) and Src kinase (show CSK Antibodies) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC Antibodies)
lack of ROS (show ROS1 Antibodies) production because of NADPH oxidase (show NOX1 Antibodies) deficiency results in the production of higher levels of proinflammatory mediators from neutrophils and macrophages, which may at least partly contribute to the exacerbation of nonviable Candida albicans-Induced Inflammation in mouse lungs.
the present study demonstrates that nNOS-derived NO signaling modulated by spinal Sig-1R activation increases Nox2 activity and concomitant ROS production, which leads to a ROS-induced increase in PKC-dependent pGluN1 expression in the spinal cord dorsal horn and the development of pain hypersensitivity
Findings indicate the role of Tiam1 (show TIAM1 Antibodies)-Rac1-Nox2 signaling pathway in the onset of spontaneous diabetes in the type 1 diabetes NOD mouse model.
Data show that Ewha-18278 displayed NADPH oxidase 2 (Nox2) inhibition.
Data suggested that NADPH oxidase 2-derived reactive oxygen species in hippocampal microglia, at least in part, contributes to subsequent neuroinflammation and cognitive impairments induced by surgery in aged mice.
results indicate that long-term UVA eye irradiation led to increased gp91phox-derived ROS (show ROS1 Antibodies) in the brain and the increased expression of urocortin 2 (show UTS2 Antibodies) and CRHR (show CRHR1 Antibodies) type 2, resulting in photoaging; however, further studies are needed to confirm these findings
NADPH oxidase 2 inactivation causes regression of vascularization and the size and stability of atherosclerotic plaques
Nox2 is implicated in the inflammatory and neovascular response to corneal chemical injury in mice
sub-vasomotor concentration of ET-1 (show EDN1 Antibodies) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 Antibodies) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 Antibodies) following ETA receptor activation
Reactive oxygen species generated by NADPH oxidase (show NOX1 Antibodies) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.
Upregulation of PPAR-gamma (show PPARG Antibodies) and NADPH (show NQO1 Antibodies) oxidases are involved in restenosis.
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
cytochrome b-245, beta polypeptide
, NADPH oxidase 2
, cytochrome b-245, beta polypeptide (chronic granulomatous disease)
, Cytochrome b-245 heavy chain
, NADPH oxidase heavy chain subunit
, NADPH oxidase 1
, NADPH oxidase flavocytochrome b subunit
, cytochrome b-245 heavy chain
, cytochrome b(558) subunit beta
, cytochrome b558 subunit beta
, heme-binding membrane glycoprotein gp91phox
, neutrophil cytochrome b 91 kDa polypeptide
, p22 phagocyte B-cytochrome
, superoxide-generating NADPH oxidase heavy chain subunit
, endothelial type gp91-phox
, predicted NADPH oxidase-2