CYBB antibody
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- Target See all CYBB Antibodies
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This CYBB antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- NOX2/gp91phox Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human NOX2/gp91phox .
- Isotype
- IgG
- Top Product
- Discover our top product CYBB Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
- Alternative Name
- CYBB (CYBB Products)
- Synonyms
- zgc:64144 antibody, cgd antibody, gp91-1 antibody, gp91-phox antibody, gp91phox antibody, nox2 antibody, NOX2 antibody, cybb antibody, NOX1 antibody, AMCBX2 antibody, CGD antibody, GP91-1 antibody, GP91-PHOX antibody, GP91PHOX antibody, p91-PHOX antibody, Nox2 antibody, C88302 antibody, CGD91-phox antibody, Cgd antibody, Cyd antibody, Gp91-phox antibody, CYBB antibody, cytochrome b-245, beta polypeptide (chronic granulomatous disease) antibody, cytochrome b-245, beta polypeptide antibody, cytochrome b-245 heavy chain antibody, cytochrome b-245, beta polypeptide L homeolog antibody, cytochrome b-245 beta polypeptide antibody, cytochrome b-245 beta chain antibody, NADPH oxidase heavy chain subunit antibody, cybb antibody, CYBB antibody, cybb.L antibody, Cybb antibody, GP91-PHOX antibody
- Background
- Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008],AMCBX2;CGD;GP91-1;GP91-PHOX;GP91PHOX;IMD34;NOX2;p91-PHOX;CYBB,Cancer,Endocrine & Metabolism,Immunology & Inflammation,CYBB
- Molecular Weight
- 65kDa
- Gene ID
- 1536
- UniProt
- P04839
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