Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Additionally we are shipping DNMT3A Kits (5) and many more products for this protein.
Showing 10 out of 10 products:
DNMT3A haploinsufficiency results in reversible epigenetic alterations that transform FLT3 (show FLT3 Antibodies)(ITD)-mutant myeloproliferative neoplasm into AML (show RUNX1 Antibodies).
Dnmt3a-cKO muscles exhibit fewer Pax7 (show PAX7 Antibodies)+ SCs (show TWIST1 Antibodies), which show increased expression of p57Kip2 (show CDKN1C Antibodies) protein
Study provides evidence that Arg882-mutated DNMT3A contributes to acute myeloid leukemia (show BCL11A Antibodies) pathogenesis through epigenetic activation of leukemia-related genes.
Dnmt3a is a haplo-insufficient (show TGFb Antibodies) tumor suppressor in chronic lymphocytic leukemia and highlights the importance of deregulated molecular events in disease pathogenesis.
Cigarette smoke induces proteosomal-mediated degradation of DNMT3a in embryonic orofacial cells.
The stress-induced Brg1 (show SMARCA4 Antibodies)-G9a (show EHMT2 Antibodies)/GLP (show GOLGA6A Antibodies)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Antibodies) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.
both the PML (show PML Antibodies)-RARA (show RARA Antibodies)-driven competitive transplantation advantage and development of acute promyelocytic leukemia (show PML Antibodies) (APL (show FASL Antibodies)) required DNMT3A
Overexpression or knockdown of medial prefrontal cortex Dnmt3a levels decreases or increases anxiety-like behavior, respectively.
DKO cardiomyocytes showed virtual absence of targeted Dnmt3a and Dnmt3b (show DNMT3B Antibodies) mRNA transcripts.
An unexpected oncogenic role for Dnmt3a in MTCL through methylation-independent repression of Dnmt3b (show DNMT3B Antibodies).
This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene causes developmental defects in multiple different organ systems. There is a pseudogene for this gene located on chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
DNA (cytosine-5)-methyltransferase 3A
, DNA MTase MmuIIIA
, DNA methyltransferase MmuIIIA
, DNA methyltransferase 3A