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Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 Proteins (DYRK2)

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. Additionally we are shipping DYRK2 Antibodies (89) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DYRK2 8445 Q92630
DYRK2 69181 Q5U4C9
Rat DYRK2 DYRK2 314862  
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Top DYRK2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

DYRK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) Interaction Partners

Human Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) interaction partners

  1. Silencing of DYRK2 increases cell proliferation but reverses CAM (show CALM1 Proteins)-DR in Non-Hodgkin's Lymphoma

  2. DYRK2 may regulate EMT (show ITK Proteins) through Snail (show SNAI1 Proteins) degradation in ovarian SA and might be a predictive marker for a favorable prognosis in the treatment of this cancer.

  3. Downregulation of DYRK2 is associated with recurrence in early stage breast cancer.

  4. DYRK2-dependent phosphorylation of pregnane X receptor facilitates its subsequent ubiquitination by UBR5.

  5. DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail (show SNAI1 Proteins).

  6. DYRK2-mediated phosphorylation of p53 (show TP53 Proteins) at Ser46 is impaired under hypoxic conditions, suggesting a molecular mechanism underlying chemotherapy resistance in solid tumors.

  7. Data indicate that Dyrk2 phosphorylates TERT (show TERT Proteins) protein, which is then associated with the EDD-DDB1 (show DDB1 Proteins)-VprBP E3 ligase complex for subsequent ubiquitin-mediated TERT (show TERT Proteins) protein degradation.

  8. DYRK2 regulates tumor progression through modulation of c-Jun (show JUN Proteins) and c-Myc (show MYC Proteins)

  9. The findings indicate that ATM (show ATM Proteins) controls stability and pro-apoptotic function of DYRK2 in response to DNA damage.

  10. These findings indicate that DYRK2 regulates p53 (show TP53 Proteins) to induce apoptosis in response to DNA damage.

Zebrafish Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) interaction partners

  1. These results suggest that the phosphorylation of Dpysl2 (show DPYSL2 Proteins) and Dpysl3 (show DPYSL3 Proteins) by Cdk5 (show CDK5 Proteins) and DYRK2 is required for the proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish embryos.

Mouse (Murine) Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) interaction partners

  1. DYRK2 regulates tumor progression through modulation of c-Jun (show JUN Proteins) and c-Myc (show MYC Proteins)

DYRK2 Protein Profile

Protein Summary

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.

Gene names and symbols associated with DYRK2

  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2)
  • dual specificity tyrosine-phosphorylation-regulated kinase 2 (CpipJ_CPIJ014802)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (dyrk2)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (Dyrk2)
  • 1810038L18Rik protein
  • DYRK2 protein
  • fc18c09 protein
  • si:ch211-266a5.8 protein
  • wu:fa09g03 protein
  • wu:fc18c09 protein

Protein level used designations for DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 , dual specificity tyrosine-phosphorylation-regulated kinase 2

GENE ID SPECIES
452061 Pan troglodytes
6047972 Culex quinquefasciatus
8445 Homo sapiens
557602 Danio rerio
427864 Gallus gallus
69181 Mus musculus
314862 Rattus norvegicus
481152 Canis lupus familiaris
514916 Bos taurus
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