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ELOVL3 plays a role in fatty acid chain elongation and formation of neutral lipids required for skin barrier function (Westerberg et al., 2004 [PubMed 14581464]).[supplied by OMIM, Mar 2008].. Additionally we are shipping and many more products for this protein.
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Data (including data from studies in knockout mice) suggest signal transduction via calcitriol/calcitriol receptor regulates expression of Elovl3 (fatty acid elongase 3) and alters fatty acid composition in subcutaneous (not visceral) adipose tissue.
that ablation of ELOVL3 leads to reduced adiponectin levels, constrained expansion of adipose tissue, and resistance against diet-induced obesity, a situation that is more exaggerated in female mice
ELOVL3 and fatty acid chain length play roles in development of hair and skin function
In the present study, we show that the cold-induced Elovl3 expression is under the control of peroxisome proliferator-activated receptor-alpha (PPARalpha (show PPARA Antibodies).
ELOVL3 is an important regulator of endogenous synthesis of saturated very long chain fatty acids and triglyceride formation in brown adipose tissue during the early phase of the tissue recruitment
The Elovl3 gene upstream region was repressed by RevErbalpha (show NR1D1 Antibodies) and activated by sterol-regulatory element binding protein-1 (SREBP1 (show SREBF1 Antibodies)) transcription factors.
Elovl3 expression in mouse liver is under strict diurnal control by circulating steroid hormones such as glucocorticoids and androgens
ELOVL3 plays a role in fatty acid chain elongation and formation of neutral lipids required for skin barrier function (Westerberg et al., 2004
3-keto acyl-CoA synthase Elovl3
, ELOVL FA elongase 3
, ELOVL fatty acid elongase 3
, cold inducible glycoprotein 30
, cold-inducible glycoprotein of 30 kDa
, elongation of very long chain fatty acids protein 3
, elongation of very long chain fatty acids-like 3
, very-long-chain 3-oxoacyl-CoA synthase 3
, 3-keto acyl-CoA synthase ELOVL3
, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3