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EPS8L2 encodes a member of the EPS8 gene family. Additionally we are shipping EPS8-Like 2 Antibodies (56) and EPS8-Like 2 Kits (2) and many more products for this protein.
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frame-shift variant (c.1014delC; p.Ser339Alafs*15) was identified in EPS8L2, encoding Epidermal growth factor receptor Pathway Substrate 8 (show EPS8 Proteins) L2, a protein of hair cells' stereocilia previously implicated in progressive deafness in the mouse
Eps8L2 is required for the long-term maintenance of the staircase structure and mechanosensory function of auditory hair bundles.
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling.
, EPS8-like protein 2
, EPS8-related protein 2
, epidermal growth factor receptor kinase substrate 8-like protein 2
, epidermal growth factor receptor pathway substrate 8-related protein 2
, EPS8 related protein 2
, epidermal growth factor receptor pathway substrate 8-like protein 2