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ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Additionally we are shipping Endoglin Kits (53) and Endoglin Proteins (52) and many more products for this protein.
Showing 10 out of 700 products:
Human Monoclonal ENG Primary Antibody for FACS - ABIN4896996
Choi, Shin, Lee, Park, Park, Nam, Kim, Woo, Yoon, Kang, Ra, Youn, Hong: Transplantation of CTLA4Ig gene-transduced adipose tissue-derived mesenchymal stem cells reduces inflammatory immune response and improves Th1/Th2 balance in experimental autoimmune thyroiditis. in The journal of gene medicine 2011
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Human Monoclonal ENG Primary Antibody for FACS, IHC (fro) - ABIN238459
Guo, Slevin, Li, Parameshwar, Liu, Kumar, Bernabeu, Kumar: CD105 inhibits transforming growth factor-beta-Smad3 signalling. in Anticancer research 2004
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Human Monoclonal ENG Primary Antibody for FACS, ICC - ABIN810077
Zhu, Sun, Xie, Jin, Sheibani, Greenberg: Hypoxic induction of endoglin via mitogen-activated protein kinases in mouse brain microvascular endothelial cells. in Stroke; a journal of cerebral circulation 2003
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Horse (Equine) Monoclonal ENG Primary Antibody for FACS - ABIN118831
Haruta, Seon: Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6. in Proceedings of the National Academy of Sciences of the United States of America 1986
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Mouse (Murine) Monoclonal ENG Primary Antibody for FACS - ABIN4896370
Madhu, Li, Dighe, Balian, Cui et al.: BMP-non-responsive Sca1+ CD73+ CD44+ mouse bone marrow derived osteoprogenitor cells respond to combination of VEGF and BMP-6 to display enhanced osteoblastic differentiation and ectopic bone ... in PLoS ONE 2014
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Human Polyclonal ENG Primary Antibody for EIA, WB - ABIN951149
Ríus, Smith, Almendro, Langa, Botella, Marchuk, Vary, Bernabéu: Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. in Blood 1999
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Human Polyclonal ENG Primary Antibody for IHC, WB - ABIN2777735
Sanz-Rodriguez, Guerrero-Esteo, Botella, Banville, Vary, Bernabéu: Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. in The Journal of biological chemistry 2004
Akt (show AKT1 Antibodies) level was reduced in preeclamptic placentas relative to preterm control. Inhibition of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) resulted in significantly elevated soluble endoglin release from endothelial cells, had no effect on MMP14 (show MMP14 Antibodies) mRNA expression but resulted in significantly reduced TIMP3 (show TIMP3 Antibodies). In contrast inhibiting PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) in placental explants or primary trophoblast did not change soluble endoglin release.
the TGFbeta1 (show TGFB1 Antibodies) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload
Increased ENG gene expression is associated with the Risk of Hepatocellular Carcinoma.
Study of four patients with pulmonary arterial hypertension associated with human immunodeficiency virus infection found predisposing mutations in the BMPR2 (show BMPR2 Antibodies), ACVRL1 (show ACVRL1 Antibodies) and ENG genes.
These results suggest that KLF6 (show KLF6 Antibodies) regulates MMP14 (show MMP14 Antibodies) transcription and is a critical player of the gene expression network triggered during endothelial repair.
In placenta, higher Eng immunoexpression was observed in both villi types of the preeclamptic compared to normotensive groups. Irrespective of pregnancy type (normotensive versus preeclampsia), there was no significant effect of HIV status on Eng immunoexpression within the exchange and conducting villi
Report marginal prognostic significance of endoglin expression in pancreatic ductal adenocarcinoma.
CD105 acts as one of the receptors of TGF-beta1 (show TGFB1 Antibodies) on vascular endothelial cells and induces the angiogenic pathway in oral squamous cell carcinoma.
Endoglin-induced peritoneal mesothelial cell senescence may contribute to peritoneal dissemination of gastric cancer cells
These results suggest a critical role for endoglin in integrin-mediated adhesion of mural cells.
Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.
Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.
The changes in CD90 (show THY1 Antibodies) and CD105 expression in the testis and ovary of mice are reported.
the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.
These results demonstrate a requirement for endoglin in descendants of Pax3 (show PAX3 Antibodies)-expressing vascular cell precursors.
The similarities in Eng-/- and Mlc2a-/- embryos suggest that Eng-/- mice may suffer from a primary heart developmental defect and secondary defects in vessel patterning.
results of our study provide evidence of endoglin as a valid target for cancer therapy and support further development of plasmid shRNA delivery, which have prolonged antitumor effect, especially in combined schedules
ENG deficiency leads to EC hyperpermeability through constitutive activation of RhoA (show RHOA Antibodies) and destabilization of endothelial barrier function.
endoglin is not localized with cell adhesion molecules involved in atherosclerosis, suggesting it might not participate in leukocyte accumulation in aorta of apoE (show APOE Antibodies)-deficient mice during atherogenesis
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
endoglin (Osler-Rendu-Weber syndrome 1)
, CD105 antigen
, cell surface MJ7/18 antigen
, transmembrane glycoprotein