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The protein encoded by EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Additionally we are shipping EDNRB Kits (18) and EDNRB Proteins (9) and many more products for this protein.
Showing 10 out of 96 products:
Human Polyclonal EDNRB Primary Antibody for WB - ABIN1107094
Arai, Nakao, Takaya, Hosoda, Ogawa, Nakanishi, Imura: The human endothelin-B receptor gene. Structural organization and chromosomal assignment. in The Journal of biological chemistry 1993
Show all 4 references for ABIN1107094
Human Polyclonal EDNRB Primary Antibody for WB - ABIN927147
Ehrenreich, Nau, Dembowski, Hasselblatt, Barth, Hahn, Schilling, Sirén A-L, Brück: Endothelin b receptor deficiency is associated with an increased rate of neuronal apoptosis in the dentate gyrus. in Neuroscience 2000
Human Polyclonal EDNRB Primary Antibody for FACS, IF - ABIN390760
MacClellan, Howard, Cole, Stine, Giles, OConnell, Wozniak, Stern, Mitchell, Kittner: Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study. in Stroke; a journal of cerebral circulation 2009
EDNRB plays a key role in hypoxia tolerance
The increased gene expression of MITF (show MITF Antibodies) and EDNRB in UVB-exposed NHMs.
culturing of reconstructed skin with microvascular endothelial cells led to increased skin pigmentation that could be prevented by inhibiting EDNRB
Polymorphisms of the EDNRB gene may influence the susceptibility to obesity and can interact with plasma arsenic levels
Cumulative effects of the RET (show RET Antibodies) and EDNRB genes contribute to long-segment and total colonic aganglionosis.
Endothelin receptor B expression was significantly lower while higher staining grade was found in basal cell carcinoma rather than squamous cell carcinoma or psoriasis.
The aim was to quantify the density of ETA and ETB receptors in cardiopulmonary tissue from pulmonary arterial hypertension patients and the monocrotaline (MCT (show MCAT Antibodies)) rat.
effect of SNP polymorphisms of EDN1 (show EDN1 Antibodies), EDNRA (show EDNRA Antibodies), and EDNRB gene on ischemic stroke
The results show that MitA (show TMEM173 Antibodies) can effectively be used to block ETBR mediated vasoconstriction as a supplement to an existing ischemic stroke therapy.
Identification of heterozygous deletion of the entire EDNRB in a father and 2 children. Since heterozygous deletion was the only change identified in EDNRB, the family represents one of the few cases of autosomal dominant inheritance of Waardenburg type 4
we show that ET-1 (show EDN1 Antibodies) acts selectively through EDNRB on astrocytes-and not oligodendrocyte progenitor cells-to indirectly inhibit remyelination.
The cardiac expression of prepro-endothelin-1 (show EDN1 Antibodies) mRNA, endothelin-converting enzyme-1 (show ECEL1 Antibodies) mRNA, and protein and endothelin receptors A and B mRNA was increased in 18-week-old obese C57BL/6 mice compared to animals with normal weight
results indicate that the Notch1 (show NOTCH1 Antibodies)-STAT3 (show STAT3 Antibodies)-ETB(R) axis connects a signaling network that promotes reactive astrocyte proliferation after brain injury
Ednrb-deficient mice showed altered goblet cell differentiation and surface mucus properties characteristic of human Hirschsprung disease.
pathophysiological events in the brain in sepsis mediated by ET-1 (show EDN1 Antibodies)/ETB receptor axis, were evaluated.
PROD (show TAF8 Antibodies)-rol/rol mice with classic piebald mutation have two mutant genes, Ednrb and Cacna1a (show CACNA1A Antibodies).
Enterocolitis causes profound lymphoid depletion in endothelin receptor B- and endothelin 3 (show EDN3 Antibodies)-null mouse models of Hirschsprung-associated enterocolitis.
ednrb expression in the heart was restricted to the endocardium and coronary endothelium
Podocyte endothelin type B receptors significantly contribute to diabetes-induced activation of the beta-catenin (show CTNNB1 Antibodies) cascade.
PDE5 (show PDE5A Antibodies) inhibition and increase in cGMP produce pulmonary vasodilation that is mediated in part through inhibition of the ET pathway, thereby precluding an additional vasodilator effect of ETA/ETB receptor blockade in the presence of PDE5 (show PDE5A Antibodies) inhibition.
ET(A (show EDNRA Antibodies))/ET(B) blockade decreased pulmonary vascular resistance but only during exercise.
endothelial endothelin ET(B) receptors induce NO and EDHF mediated vasodilatation in porcine coronary arteries; in organ culture, endothelial endothelin ET(B) receptors are down-regulated
PKC (show FYN Antibodies) and MAPK (show MAPK1 Antibodies) seem to be involved in the regulation of endothelin type A and type B receptor expression in porcine coronary arteries
extracellular ET-1 (show EDN1 Antibodies) regulates the abundance of ET-1 (show EDN1 Antibodies) mRNA in PAECs, in an ETB receptor-dependent manner, by modulating both mRNA stability and transcription via mechanisms involving receptor endocytosis and both ERK (show MAPK1 Antibodies) and p38 MAPK (show MAPK14 Antibodies) pathways
Differential cell-specific and spatiotemporal expression of the EDN1 (show EDN1 Antibodies) system and NOS (show NOS Antibodies) in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.
Elevated local expression of ET-1 (show EDN1 Antibodies) and Ednra/Ednrb during the peri (show PLIN1 Antibodies)-ovulatory period induces the high contractile activity of the oviduct to optimize gamete transport.
Hyperinsulinemia caused significant changes in endothelin receptor expression, which suggested that ETR (show EDNRA Antibodies) antagonists might be beneficial for treatment of laminitis in horses.
both ETA and ETB receptors are involved in the net tonic response to ET-1 (show EDN1 Antibodies) in normal laminar veins; a population of ETB receptors may be present on the vascular endothelium and on smooth muscle of laminar veins
Stimulation of ETA and ETB receptors activates native protein kinase C-dependent transient receptor potential channel (TRPC)1 through phospholipid pathways involving phosphoinositol-3,4,5-trisphosphate (PIP)3 and PIP2 in coronary artery myocytes.
ET(B) receptor stimulation relaxes the carbachol precontracted iris sphincter muscle, an effect that is mediated by the ET(B2) receptor subtype, through NO and the release of prostaglandins.
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
endothelin receptor type B
, endothelin B receptor
, endothelin receptor B
, endothelin-B receptor
, endothelin receptor non-selective type
, endothelin receptor subtype B
, endothelin ETB receptor