EDNRB antibody (C-Term)
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- Target See all EDNRB Antibodies
- EDNRB (Endothelin Receptor Type B (EDNRB))
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Binding Specificity
- AA 406-439, C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EDNRB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Endothelin B receptor(EDNRB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- QSFEEKQSLE EKQSCLKFKA NDHGYDNFRS SNKY
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Endothelin B receptor(EDNRB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: endothelin receptor type B
Protein Name: Endothelin B receptor - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human EDNRB (406-439aa QSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY), different from the related mouse and rat sequences by one amino acid.
- Isotype
- IgG
- Top Product
- Discover our top product EDNRB Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Alternative Name
- EDNRB (EDNRB Products)
- Synonyms
- ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
- Background
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Endothelin receptor type B, also known as ETB is a protein that in humans is encoded by the EDNRB gene. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: ABCDS antibody|Ednra antibody|Ednrb antibody|EDNRB_HUMAN antibody|Endothelin B receptor antibody|Endothelin B receptor precursor antibody|Endothelin receptor Non selective type antibody|Endothelin receptor non-selective type antibody|Endothelin receptor type B antibody|ET B antibody|ET-B antibody|ET-BR antibody|ETB antibody|ETBR antibody|ETRB antibody|Hirschsprung disease 2 antibody|HSCR antibody|HSCR2 antibody|OTTHUMP00000018534 antibody|OTTHUMP00000178736 antibody|WS4A antibody - Gene ID
- 1910
- UniProt
- P24530
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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