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anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) Antibodies

FIP1L1 encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. Additionally we are shipping FIP1 Like 1 (S. Cerevisiae) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FIP1L1 81608 Q6UN15
FIP1L1 289582 Q5U317
FIP1L1 66899 Q9D824
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Top anti-FIP1 Like 1 (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FIP1L1 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate Rabbit Anti-FIP1L1 Antibody ,Paraffin Embedded Tissue: Human Brain cell  Cellular Data: Epithelial cells of renal tubule  Antibody Concentration: 4.0-8.0 µg/mL  Magnification:.00X 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: FIP1L1 Antibody [NBP1-85064] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Western Blot: FIP1L1 Antibody [NBP1-85064] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: FIP1L1 Antibody [ABIN2616669] - Human breast carcinoma. Antibody used at a dilution of 1:5,000. 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: FIP1L1 Antibody [ABIN2616658] - Human pancreatic islet cell tumor. Antibody used at a dilution of 1:1,000. 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of FIP1L1 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Immunohistochemical analysis of FIP1L1 staining in mouse liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using FIP1L1 antibody. Immunohistochemistry of paraffin-embedded mouse liver using FIP1L1 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 14 Days
$323.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged FIP1L1 is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (67.32 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details

FIP1L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FIP1 Like 1 (S. Cerevisiae) Antibodies

  1. Chicken Polyclonal FIP1L1 Primary Antibody for WB - ABIN2776582 : Zhao, Oberg, Rush, Fay, Lambkin, Schwartz: A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein. in Journal of virology 2005 (PubMed)

  2. Human Polyclonal FIP1L1 Primary Antibody for ICC, IF - ABIN4311958 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against FIP1 Like 1 (S. Cerevisiae) Interaction Partners

Human FIP1 Like 1 (S. Cerevisiae) (FIP1L1) interaction partners

  1. F604S exchange in FIP1L1-PDGFRA (show PDGFRA Antibodies) enhances FIP1L1-PDGFRA (show PDGFRA Antibodies) protein stability via SHP-2 (show PTPN11 Antibodies) and SRC (show SRC Antibodies) and is associated with kinase inhibitor resistance in hypereosinophilic syndrome and chronic eosinophilic leukemia.

  2. FIP1L1 differentially contributes to the pathogenesis of distinct types of leukemia.

  3. FP fusion gene favors secondary KIT mutations in MCs (show SMCP Antibodies) via growth and proliferation signals or that a yet unknown mechanism causes genomic instability with independent evolution of FP and KIT D816V

  4. Oncostatin M (show OSM Antibodies) is a FIP1L1/PDGFRA (show PDGFRA Antibodies)-dependent mediator of cytokine production in chronic eosinophilic leukemia.

  5. description of polycythemia vera (show IGF2BP3 Antibodies) concurrent with FIP1L1-PDGFRA (show PDGFRA Antibodies)-positive myeloproliferative neoplasm with eosinophilia [case report]

  6. Data show that the cyclin-dependent kinase 7/9 inhibitor (CDK7/9 inhibitor) potently inhibits FIP1L1-PDGFRalpha-positive Bcr-Abl-positive chronic myeloid leukemia (CML) cells.

  7. results strongly suggest that JAK2 (show JAK2 Antibodies) is activated by Fip1 (show RRAGA Antibodies)-like1 (FIP1L1)-platelet-derived growth factor receptor alpha (show PDGFRA Antibodies) (F/P) and is required for F/P stimulation of cellular proliferation and infiltration in chronic eosinophilic leukemia

  8. Treatment with imatinib is associated with an excellent prognosis in FIP1L1-PDGFRA (show PDGFRA Antibodies)-positive chronic eosinophilic leukemia in first chronic phase

  9. FIP1L1/PDGFRA (show PDGFRA Antibodies) fusion gene-positive myeloproliferative disorders with eosinophilia are discussed.

  10. The hypereosinophilic syndrome may result from a novel fusion tyrosine kinase (show TXK Antibodies) - FIP1L1-PDGFRalpha - that is a consequence of an interstitial chromosomal deletion.

Mouse (Murine) FIP1 Like 1 (S. Cerevisiae) (FIP1L1) interaction partners

  1. FIP1L1-PDGFRalpha activation requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent

FIP1 Like 1 (S. Cerevisiae) (FIP1L1) Antigen Profile

Protein Summary

This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with FIP1L1

  • factor interacting with PAPOLA and CPSF1 (fip1l1) antibody
  • FIP1 like 1 (S. cerevisiae) (FIP1L1) antibody
  • factor interacting with PAPOLA and CPSF1 (FIP1L1) antibody
  • factor interacting with PAPOLA and CPSF1 (Fip1l1) antibody
  • FIP1 like 1 (S. cerevisiae) (Fip1l1) antibody
  • FIP1 like 1b (S. cerevisiae) (fip1l1b) antibody
  • 1300019H17Rik antibody
  • FIP1 antibody
  • fip1l1 antibody
  • hFip1 antibody
  • Rhe antibody
  • Rje antibody
  • wu:fd36f11 antibody
  • zgc:103421 antibody

Protein level used designations for FIP1L1

FIP1 like 1 , FIP1-like 1 protein , pre-mRNA 3'-end-processing factor FIP1 , FIP1L1 cleavage and polyadenylation specific factor subunit , factor interacting with PAP , rearranged in hypereosinophilia

GENE ID SPECIES
733481 Xenopus (Silurana) tropicalis
100172699 Pongo abelii
81608 Homo sapiens
494780 Xenopus laevis
289582 Rattus norvegicus
422754 Gallus gallus
612980 Canis lupus familiaris
100138550 Bos taurus
66899 Mus musculus
450021 Danio rerio
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