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anti-GRIP and Coiled-Coil Domain Containing 2 (GCC2) Antibodies

The protein encoded by GCC2 is a peripheral membrane protein localized to the trans-Golgi network.

list all antibodies Gene Name GeneID UniProt
GCC2 9648 Q8IWJ2
GCC2 70297  
GCC2 309798 D3ZZL9
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Top anti-GRIP and Coiled-Coil Domain Containing 2 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with AP51797PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Western blot analysis of GCC2 Antibody (C-term) in mouse stomach tissue lysates (15ug/lane). This demonstrates the GCC2 antibody detected GCC2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB GCC2 Antibody (C-term)  western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the GCC2 antibody detected GCC2 protein (arrow). GCC2 antibody (C-term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the GCC2 antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA   0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Goat Un-conjugated IHC (p), ELISA 50 μg Log in to see 11 to 13 Days
$541.80
Details

GCC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus) , ,


Top referenced anti-GRIP and Coiled-Coil Domain Containing 2 Antibodies

  1. Human Polyclonal GCC2 Primary Antibody for EIA, IHC (p) - ABIN952473 : Hayes, Brown, Haas, Nottingham, Barr, Pfeffer: Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi. in Molecular biology of the cell 2009 (PubMed)
    Show all 5 references for ABIN952473

More Antibodies against GRIP and Coiled-Coil Domain Containing 2 Interaction Partners

Human GRIP and Coiled-Coil Domain Containing 2 (GCC2) interaction partners

  1. These unexpected features support a model in which GCC185 collapses onto the Golgi surface, perhaps by binding to Rab (show HRB Antibodies) GTPases, to mediate vesicle tethering.

  2. Deletion of the ARL4A (show ARL4A Antibodies)-interacting region of GCC185 results in inability to maintain Golgi structure and modulate endosome-to-Golgi transport.

  3. Two distinct domains of GCC185 are needed either for Golgi structure maintenance or transport vesicle tethering. The domain needed for vesicle tethering binds to the clathrin adaptor AP-1 (show FOSB Antibodies).

  4. The ability of the four mammalian GRIP domain proteins, p230 (show GOLGA4 Antibodies), golgin-97 (show GOLGA1 Antibodies), GCC88 (show GCC1 Antibodies), and GCC185 to interact is reported.

  5. These data assign a specific pathway to an interesting, TGN (show TG Antibodies)-localized protein and suggest that GCC185 may participate in the docking of late endosome-derived, Rab9 (show RAB9A Antibodies)-bearing transport vesicles at the TGN (show TG Antibodies).

  6. GCC2 is required for endosome-to-Golgi transport and maintenance of Golgi structure.

  7. Rab (show HRB Antibodies) and Arl GTPase (show RACGAP1 Antibodies) family members cooperate in the localization of GCC2.

  8. Results show that GCC185 contains at least six binding sites for as many as 14 different Rab (show HRB Antibodies) GTPases across its entire length.

  9. Study demonstrates that Golgi recruitment of endogenous GCC185 does not involve Rab6A/A' and Arl1.

GRIP and Coiled-Coil Domain Containing 2 (GCC2) Antigen Profile

Protein Summary

The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GCC2

  • GRIP and coiled-coil domain containing 2 (GCC2) antibody
  • GRIP and coiled-coil domain containing 2 (gcc2) antibody
  • GRIP and coiled-coil domain containing 2 (Gcc2) antibody
  • 0610043A03Rik antibody
  • 2210420P05Rik antibody
  • 2600014C01Rik antibody
  • AW112121 antibody
  • GCC185 antibody
  • Lims1 antibody
  • mKIAA0336 antibody
  • RANBP2L4 antibody
  • REN53 antibody

Protein level used designations for GCC2

GRIP and coiled-coil domain containing 2 , GRIP and coiled-coil domain-containing 2 , GRIP and coiled-coil domain-containing protein 2 , GRIP and coiled-coil domain-containing protein 2-like , 185 kDa Golgi coiled-coil protein , CLL-associated antigen KW-11 , CTCL tumor antigen se1-1 , GCC protein, 185-kD , Golgi coiled-coil protein GCC185 , Ran-binding protein 2-like 4 , renal carcinoma antigen NY-REN-53 , GCC185 , LIM and senescent cell antigen-like domains 1

GENE ID SPECIES
428014 Gallus gallus
459476 Pan troglodytes
474541 Canis lupus familiaris
539484 Bos taurus
100061081 Equus caballus
100158612 Xenopus (Silurana) tropicalis
100358853 Oryctolagus cuniculus
100388147 Callithrix jacchus
100512405 Sus scrofa
100545407 Meleagris gallopavo
100556896 Anolis carolinensis
9648 Homo sapiens
70297 Mus musculus
309798 Rattus norvegicus
Selected quality suppliers for anti-GRIP and Coiled-Coil Domain Containing 2 (GCC2) Antibodies
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