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Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. Additionally we are shipping GNAI1 Proteins (12) and many more products for this protein.
Showing 10 out of 67 products:
Human Polyclonal GNAI1 Primary Antibody for ELISA, WB - ABIN561067
Sasaki, Yamasaki, Omotuyi, Mishina, Ueda: Age-dependent dystonia in striatal G?7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole. in Journal of neurochemistry 2013
Chicken Polyclonal GNAI1 Primary Antibody for WB - ABIN2785808
Hurst, Henkel, Brown, Hooks: Endogenous RGS proteins attenuate Galpha(i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells. in Cellular signalling 2008
Cow (Bovine) Polyclonal GNAI1 Primary Antibody for WB - ABIN265063
Li, Mumby, Greenwood, Jope: Pertussis toxin-sensitive G protein alpha-subunits: production of monoclonal antibodies and detection of differential increases on differentiation of PC12 and LA-N-5 cells. in Journal of neurochemistry 1995
Human Polyclonal GNAI1 Primary Antibody for IHC, IHC (p) - ABIN441599
Matsumura, Kojidani, Kamioka, Uchida, Haraguchi, Kimura, Toyoshima: Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. in Nature communications 2016
stimulation of GPR17 (show GPR17 Antibodies) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP Antibodies) expression levels mainly by triggering the Galphai/o signaling pathway.
Gnai1 missense mutation is responsible of hyperpigmentation in mouse model.
acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.
Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.
By using mice deficient in individual Galphai/o G-protein subunits, authors demonstrate that Galphai1 and Galphai3 are the critical in vivo targets of ADP-ribosylation underlying vasoactive amine sensitization elicited by pertussis toxin exposure.
leucine can directly facilitate insulin (show INS Antibodies) signaling through a Galphai protein-dependent intracellular signaling pathway
Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.
Mice with mutations of Gnai1 or Gnai2 (show GNAI2 Antibodies) have neither fusions of ribs nor lumbar vertebrae, but loss of both Gnai3 (show GNAI3 Antibodies) and one of the other two genes increases the number and severity of rib fusions without affecting the lumbar fusions.
Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (show GNAO1 Antibodies)) upon activation of mGluR6 (show GRM6 Antibodies) closes the TRPM1 (show TRPM1 Antibodies) channel, perhaps via a direct interaction.
RGS14 (show RGS16 Antibodies) can form complexes with GPCRs in cells that are dependent on Galpha (show SUCLG1 Antibodies)(i/o) and these RGS14 (show RGS16 Antibodies).Galpha (show SUCLG1 Antibodies)(i1).GPCR (show GPBAR1 Antibodies) complexes may be substrates for other signaling partners such as Ric-8A (show RIC8A Antibodies)
Data indicate that hydroxyurea (HU) induces SAR1 (show IQGAP1 Antibodies) protein expression, which in turn activates gamma-globin (show HBG1 Antibodies) expression, predominantly through the Gialpha/JNK (show MAPK8 Antibodies)/Jun (show JUN Antibodies) pathway.
Gi alpha subunit (show POLG Antibodies) was found to be a key modulator of GABAB-receptors signaling in analgesia.
AC5, by binding active Galphai1, interferes with G-protein deactivation and reassembly and thereby might sensitize its own regulation.
Data indicate that focal adhesion kinase (FAK) activation and cell migration require Src, Gi/Go, COX-2 and LOXs activities.
resistin (show RETN Antibodies) contributes to the pro-inflammatory state of SMC (show DYM Antibodies) by the up-regulation of CX3CL1 (show CX3CL1 Antibodies) and CX3CR1 (show CX3CR1 Antibodies) expression via a mechanism involving NF-kB, AP-1 (show FOSB Antibodies), and STAT1 (show STAT1 Antibodies)/3 transcription factors, (2) resistin (show RETN Antibodies) employs TLR4 (show TLR4 Antibodies) and Gi-protein signaling.
Data suggest that chemokine (show CCL1 Antibodies) binding to CCX-CKR (show CCRL1 Antibodies) (a) recruits Gi proteins and beta-arrestin (beta-arr (show SAG Antibodies)) with high affinity.
This study support a role for RGS (show PITX2 Antibodies) proteins as negative regulators of opioid supraspinal antinociception and also reveal a potential novel function of RGS (show PITX2 Antibodies) proteins as positive regulators of opioid spinal antinociceptive pathways.
Galpha(o (show GNAO1 Antibodies)) protein contributes to maximally efficient mu-opioid receptor (show OPRM1 Antibodies) signaling and antinociception in Galpha(o (show GNAO1 Antibodies)) null transgenic mice.
CXCL12 (show CXCL12 Antibodies) signaling via CXCR7 (show CXCR7 Antibodies) is Gialpha independent.
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.
adenylate cyclase-inhibiting G alpha protein
, guanine nucleotide binding protein, alpha inhibiting 1
, guanine nucleotide-binding protein G(i) subunit alpha-1
, Gi1 protein alpha-subunit
, alpha-subunit of G-protein, type G-alpha-i-1
, guanine nucleotide-binding protein G(i), alpha-1 subunit
, Gi1 protein alpha subunit
, Gi-alpha-1 protein
, guanine nucleotide binding protein (G protein), alpha inhibiting 1
, Galpha i1a