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HP encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Additionally we are shipping Haptoglobin Antibodies (332) and Haptoglobin Kits (130) and many more products for this protein.
Showing 10 out of 72 products:
Human Haptoglobin Protein expressed in Human - ABIN491578
Zapotoczna, Heilbronner, Speziale, Foster: Iron-regulated surface determinant (Isd) proteins of Staphylococcus lugdunensis. in Journal of bacteriology 2012
Show all 2 references for ABIN491578
The bifucosylated tetra-anntenary glycan of haptoglobin was upregulated in hepatocellular carcinoma patients of all etiologies.
Ovarian cancer cells express both Hp and its receptor CCR2 but only after exposure to ascitic fluid, inducing moderated cell migration; results suggest that Hp-induced changes in the cell morphology, actin cytoskeleton structure, and migration ability of tumor cells, is possibly "preparing" these cells for the potential induction of the metastatic phenotype.
Haptoglobin phenotype is unlikely to be an important modifier of cystic fibrosis (show S100A8 Proteins) phenotype.
these results demonstrate that sHP (show LAMC1 Proteins) is associated with poor prognosis of colorectal cancer patients and that HP promotes colorectal cancer cell invasion.
Haptoglobin 2-2 genotype was an independent predictor of cerebral salt wasting syndrome after subarachnoid hemorrhage.
Endothelial dysfunction may be influenced by Hp2/2 genotype in patients with type 1 diabetes with independence of classical CV risk factors.
This study suggests a possible role of haptoglobin phenotype on iron metabolism abnormalities that are observed in Parkinson disease.
The present study described differentially expressed human haptoglobin as a lung cancer serum protein biomarker, which may serve as a diagnostic and therapeutic target.
Hp 2 type is associated with elevated systolic pulmonary arterial pressure and low plasma nitrite levels in hemodialysis patients specifically in the diabetes mellitus state.
Serum levels of haptoglobin are higher in pancreatic cancer patients.
These data demonstrate that serum neutrophil haptoglobin-MMP 9 (show MMP9 Proteins) complexes appear sooner and decline more rapidly than other acute phase proteins.
An increase in serum amyloid A or haptoglobin in dairy cows with abomasal displacementis not specific for inflammation or bacterial infection; increased levels of either may indicate the presence of hepatic lipidosis.
Haptoglobin concentration may be a useful indicator for cows with postpartum reproductive disorders.
Presence in the milk of the acute phase proteins (APP (show APP Proteins)), haptoglobin (Hp) and serum amyloid A to see the relationships in cow composite and bulk tank milk samples.
Bovine granulocytes, isolated from peripheral blood of healthy cattle, contain abundant amounts of haptoglobin within the granules.
This study suggests that neutrophils and epithelial cells may play an essential role in elevating milk haptoglobin (Hp) in addition to previous suggestions that Hp may be derived from mammary tissues and circulation.
the interaction between haptoglobin genotype and vitamin E affects atherosclerotic plaque progression and stability
Exogenous haptoglobin attenuated the HbA (show HBA-A1 Proteins)-induced HO-1 (show HMOX1 Proteins) expression in vitro and in mouse model of sickle cell disease.
Suggest haptoglobin is an enhancer of inflammation after cardiac transplantation, contributing to graft rejection.
Zonulin facilitates development of acute lung injury (ALI) both by enhancing albumin (show ALB Proteins) leak and complement activation as well as increased buildup of neutrophils and cytokines during development of ALI.
Haptoglobin deficiency is associated with leakage-prone vessels via isolated VEGFA (show VEGFA Proteins) induction and/or suppressed Ang-1 (show ANGPT1 Proteins) expression, resulting in unbalanced VEGFalpha/Ang-1 (show ANGPT1 Proteins) transcription.
the Hp2-2 protein is involved in aneurysm formation and that the Hp genotype may be a useful biomarker in predicting aneurysm progression
Experimental models of colitis showed that haptoglobin has a protective role in inflammatory colitis
these studies provide direct evidence that the increased oxidative stress in Hp 2-2 atherosclerotic plaques is due to hemoglobin derived iron.
Synthetic PPAR gamma (show PPARG Proteins) ligands selectively activate PPAR gamma (show PPARG Proteins) bound to the haptoglobin gene promoter to arrest haptoglobin gene transcription.
Hp may be regarded as a regulator of the Th1 (show HAND1 Proteins)/Th2 balance in both human and murine immune systems.
crystal structure of the dimeric porcine haptoglobin-haemoglobin complex determined at 2.9 A resolution
haptoglobin has a role in oxidative status in piglets undergoing weaning-induced stress
This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, SAA (show SAA1 Proteins) and transthyretin (show TTR Proteins).
The haptoglobin was down-regulated with SNPs
Surfactant protein D (show SFTPD Proteins) and haptoglobin serum concentrations could be a diagnostic aid for equine inflammatory airway disease.
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
, binding peptide
, haptoglobin alpha(1S)-beta
, haptoglobin alpha(2FS)-beta
, haptoglobin, alpha polypeptide
, haptoglobin, beta polypeptide
, liver regeneration-related protein LRRG173
, haptoglobin-related protein
, haptoglobin alpha 1S