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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping and Histone Cluster 1, H3a Proteins (1) and many more products for this protein.
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A key role of persistent histone H3 (show HIST3H3 Antibodies) serine 10 or serine 28 phosphorylation in chemical carcinogenesis through regulating gene transcription of DNA damage response genes
AS1eRNA-driven DNA looping and activating histone modifications promote the expression of DHRS4 (show DHRS4 Antibodies)-AS1 (show PTGDR Antibodies) to economically control the DHRS4 (show DHRS4 Antibodies) gene cluster.
Data suggest that nuclear antigen Sp100C is a multifaceted histone H3 (show HIST3H3 Antibodies) methylation and phosphorylation sensor.
The authors propose that histone H3 threonine 118 phosphorylation via Aurora-A alters the chromatin structure during specific phases of mitosis to promote timely condensin I and cohesin disassociation, which is essential for effective chromosome segregation.
Hemi-methylated DNA opens a closed conformation of UHRF1 (show UHRF1 Antibodies) to facilitate its H3 histone (show HIST1H3B Antibodies) recognition.
Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK (show ZNF420 Antibodies).
Taken together, the authors verified that histone H3 (show HIST3H3 Antibodies) is a real substrate for GzmA (show GZMA Antibodies) in vivo in the Raji cells treated by staurosporin.
We conclude that circulating H3 levels correlate with mortality in sepsis patients and inversely correlate with antithrombin (show SERPINC1 Antibodies) levels and platelet counts.
Data show that H3K36me3-deficient cancers can be targeted by inhibition of WEE1 (show WEE1 Antibodies) protein.
Data show that double mutations on the residues in the interface (L325A/D328A) decreases the histone H3 (show HIST3H3 Antibodies) H3K4me2/3 demethylation activity of lysine (K)-specific demethylase 5B (KDM5B (show KDM5B Antibodies)).
Findings show that CCL2 (show CCL2 Antibodies) and CCL3 (show CCL3 Antibodies) are upregulated in the injured peripheral nerve through epigenetic histone modification in infiltrating immune cells such as macrophages.
This result suggests that the incorporation of H3.1 has a detrimental effect on the process of genome remodeling and contributes to the low success rate of somatic nuclear cloning.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
H3 histone family, member A
, histone 1, H3a
, histone H3.1
, histone H3/a