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Favors the reduction of estrogens and androgens. Additionally we are shipping HSD17B1 Proteins (8) and HSD17B1 Kits (5) and many more products for this protein.
Showing 10 out of 64 products:
Human Polyclonal HSD17B1 Primary Antibody for EIA, WB - ABIN950180
Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010
Show all 3 references for ABIN950180
Human Monoclonal HSD17B1 Primary Antibody for IHC (p), ELISA - ABIN561371
Chanplakorn, Chanplakorn, Suzuki, Ono, Chan, Miki, Saji, Ueno, Toi, Sasano: Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients. in Breast cancer research and treatment 2010
Show all 2 references for ABIN561371
Cow (Bovine) Polyclonal HSD17B1 Primary Antibody for IHC, WB - ABIN2776958
Tsuchiya, Nakao, Katoh, Sasaki, Hiroshima, Tanaka, Matsunaga, Hanaoka, Tsugane, Ikenoue: Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19. in Human reproduction (Oxford, England) 2005
A role for G143 in zebrafish 17beta-HSD (show HSD17B3 Antibodies) 1 (show SPAG8 Antibodies) and M146 and M147 in the two zebrafish paralogs prRDH (show RDH8 Antibodies) 1 and prRDH (show RDH8 Antibodies) 2, respectively, in substrate specificity.
The structure of human 17beta-HSD1 (show SPAG8 Antibodies) and biological function have been studied extensively in the last two decades. In humans, the enzyme is expressed in placenta, ovary, endometrium and breast; high activity of estrogen activation provides the basis of 17beta-HSD1 (show SPAG8 Antibodies)'s implication in estrogen-dependent diseases, such as breast cancer, endometriosis and non-small cell lung carcinomas. [Review]
These findings suggested that the HSD17B1 Ser312Gly polymorphism might confer genetic cancer susceptibility in an ethnic-dependent manner, especially among Caucasians.
The rs605059 polymorphism of the HSD17B1 gene is associated with increased risk of recurrent spontaneous abortion.
Review/Meta-analysis: HSD17B1 rs605059 polymorphisms were not associated with the risks of endometrial cancer or endometriosis.
the HSD17B1 transcript and protein were identified in HeLa, SiHa, Ca Ski (show SKI Antibodies) and C-33A cervical cancer cells.
Increased expression of HSD17B1 in NSCLC may contribute to an elevated intratissue level of E2 and consequently may support the development and spread of cancer.
The key enzymes of ovarian steroidogenesis, CYP 19 (show CYP19A1 Antibodies) and 17beta-HSD (show HSD17B3 Antibodies), are active in the ovaries of postmenopausal women.
17beta-HSD1 (show SPAG8 Antibodies) and 17beta-HSD7 are principal reductive 17beta-hydroxysteroid dehydrogenases and major players in the viability of estrogen-dependent breast cancer cells.
E1-induced ERELuc activity in the inhibitor-treated uterus was reduced by the HSD17B1 inhibitor.
Single nucleotide polymorphism in HSD17B1 gene is associated with hepatocellular carcinoma.
HSD17B1 gene was significantly associated with litter size in two populations and could be a useful molecular marker in selection for increasing litter size in pigs.
This study indicates that HSD17B1 is a key enzyme in ovarian steroidogenesis and has a novel function in initiation and stabilization of pregnancy
cellular localization of 17beta-HSD mRNA type 1 expression in the ovary, testis, skin, prostate and pituitary gland
17beta-HSD tissue distribution was studied in inbred C57BL mice of both sexes.
Androgens and estrogens are formed via the action of type 5 17beta-HSD in specific cell types in the liver, ovary, adrenal cortex, and kidney.
Activin A (show INHBA Antibodies) rapidly regulates Hsd17b1 transcription in gonadotrope and granulosa cells and may thereby regulate local 17beta-estradiol synthesis.
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
17beta-hydroxysteroid dehydrogenase type 1
, estradiol 17-beta-dehydrogenase 1
, 17-beta-hydroxysteroid dehydrogenase type 1
, 17-beta hydroxysteroid dehydrogenase
, zf 1.2
, 17-beta-HSD 1
, 20 alpha-hydroxysteroid dehydrogenase
, estradiol 17-beta-dehydrogenase-1
, hydroxysteroid (17-beta) dehydrogenase 1 isoform
, placental 17-beta-hydroxysteroid dehydrogenase
, short chain dehydrogenase/reductase family 28CE, member 1
, 17-beta-dehydrogenase 1
, Hydroxysteroid dehydrogenase 17 beta, type 1