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anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) Antibodies

IQGAP1 encodes a member of the IQGAP family. Additionally we are shipping IQGAP1 Kits (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IQGAP1 8826 P46940
IQGAP1 361598  
IQGAP1 29875 Q9JKF1
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Top anti-IQGAP1 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Goat Un-conjugated ELISA, WB ABIN308431 (0.1µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB Antibody (1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to IQGAP1 on HeLa cell (antibody concentration 10 µg/mL). IQGAP1 monoclonal antibody (M01), clone 2C5 Western Blot analysis of IQGAP1 expression in C32. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of IQGAP1 on a human endothelial cell lysate. Lane 1: 1:5000, lane 2: 1:10,000, lane 3: 1:20,000 dilution of the mouse anti-IQGAP1 antibody. Immunofluorescence staining of WI-38 cells (Human lung fibroblasts, ATCC CCL-75). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p) Formalin-fixed and rat lung tissue labeled with Anti-IQGAP1 Polyclonal Antibody, Unconjugated (ABIN737796) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and rabbit placenta tissue labeled with Anti-IQGAP1 Polyclonal Antibody, Unconjugated (ABIN737796) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$357.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB IQGAP1 Antibody (N-term)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the IQGAP1 antibody detected the IQGAP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of IQGAP1 expression in Jurkat (A), HUVEC (B), F9 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

IQGAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-IQGAP1 Antibodies

  1. Dog (Canine) Monoclonal IQGAP1 Primary Antibody for IF, IP - ABIN968063 : Hart, Callow, Souza, Polakis: IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. in The EMBO journal 1996 (PubMed)
    Show all 5 references for ABIN968063

  2. Human Monoclonal IQGAP1 Primary Antibody for IF, WB - ABIN395438 : Liang, Fu, Zhang, Tang, Zhou, Wei, Chen: Honokiol inhibits HepG2 migration via down-regulation of IQGAP1 expression discovered by a quantitative pharmaceutical proteomic analysis. in Proteomics 2010 (PubMed)
    Show all 5 references for ABIN395438

  3. Mouse (Murine) Polyclonal IQGAP1 Primary Antibody for ELISA, WB - ABIN308431 : Bi, Mancias, Goldberg: Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. in Developmental cell 2007 (PubMed)

  4. Human Polyclonal IQGAP1 Primary Antibody for IF (cc), IF (p) - ABIN737796 : Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation. in Stem cells and development 2014 (PubMed)

  5. Human Polyclonal IQGAP1 Primary Antibody for EIA, WB - ABIN615927 : Ren, Li, Sacks: IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against IQGAP1 Interaction Partners

Human IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) interaction partners

  1. Our data indicate a possible regulatory role for the multiple sclerosis-associated IKZF3 (show IKZF3 Antibodies) and IQGAP1 variants.

  2. the present study is the first to provide evidence that miR (show MLXIP Antibodies)-506 acts as a tumor suppressor, at least partially, by directly downregulating IQGAP1 in breast cancer cells.

  3. The clinical relevance of IQGAP1 as a tumor growth suppressor is supported by the finding that its expression is lower in bladder cancer compared with benign patient urothelium in multiple independent datasets.

  4. the overexpression and interactions of IQGAP1 and beta-catenin (show CTNNB1 Antibodies) contribute to hepatocellular carcinoma progression by promoting cell proliferation and migration.

  5. Down-regulation of caveolin-1 (show CAV1 Antibodies) or IQGAP1 in PC-3 (show PCSK1 Antibodies) cells reduced migration and invasion in vitro, and hypercholesterolemia-induced metastasis in vivo.

  6. Our results identify OspB as a regulator of mTORC1 and mTORC1-dependent cell proliferation early during S. flexneri infection and establish a role for IQGAP1 in mTORC1 signaling

  7. IQGAP1 critically mediates CXCR4 (show CXCR4 Antibodies) cell surface expression and signaling.

  8. Depletion of IQGAP1 disrupts nuclear envelope localization and delays abscission timing.

  9. IQGAP1 and its two isoforms regulate the actin-cytoskeleton alone and with their binding partners, Rac (show AKT1 Antibodies) and Cdc42 (show CDC42 Antibodies), thereby controlling diverse cellular processes, such as cell migration and adhesion. (Review)

  10. IQGAP1 may directly interact with estrogen receptor alpha (show ESR1 Antibodies) and serve as a signal integrator, mediating estrogen receptor alpha (show ESR1 Antibodies) transcriptional activity, cell proliferation and cell invasion during the progression of thyroid cancer.

Mouse (Murine) IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) interaction partners

  1. IQGAP1 has a strong signaling relationship with Ras genes in induction of cancer and it is considered as a key gene for induction or suppression of the hepatocellular carcinoma.

  2. IQGAP1 has the potential to modulate airway contraction severity in acute asthma.

  3. we propose that IQGAP1 acts as a small GTPase (show RACGAP1 Antibodies) scaffolding platform within the small GTPase (show RACGAP1 Antibodies) network, and recruits and/or regulates small GTPases, small GTPase (show RACGAP1 Antibodies) regulators and effectors to orchestrate cell behavior

  4. This finding has new implications for involvement of IQGAP1 in cell polarization and migration events and potentially in cell cycle-associated nuclear envelope assembly/disassembly.

  5. IQGAP1 contributes to AngII-induced apoptosis of podocytes by interacting with the ERK1/2 (show MAPK1/3 Antibodies) signaling protein

  6. RSPO (show RSPO1 Antibodies)-LGR4 (show LGR4 Antibodies) not only induces the clearance of RNF43 (show RNF43 Antibodies)/ZNRF3 (show ZNRF3 Antibodies) to increase Wnt receptor levels but also recruits IQGAP1 into the Wnt (show WNT2 Antibodies) signaling complex.

  7. IQGAP1 is upregulated in pre-existed sparing neurons of the CA1 (show CA1 Antibodies) layer undergoing morphological changes after excitoxicity-induced hippocampal CA3 (show CA3 Antibodies) neuronal death.

  8. activation of Cdc42 (show CDC42 Antibodies) in response to the insulin (show INS Antibodies) secretagogue glucose recruits endocytic machinery to IQGAP1 at the cell periphery and regulates endocytosis at this membrane site.

  9. IQGAP1 has an essential role in RAS-driven tumorigenesis in mouse and human tissue

  10. IQGAP1 localized to the endothelial cell-cell junction after sphingosine-1-phosphate (S1P (show S1PR1 Antibodies)) treatment.

IQGAP1 Antigen Profile

Protein Summary

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Gene names and symbols associated with IQGAP1

  • IQ motif containing GTPase activating protein 1 (IQGAP1) antibody
  • IQ motif containing GTPase activating protein 1 (Iqgap1) antibody
  • AA682088 antibody
  • D7Ertd237e antibody
  • D7Ertd257e antibody
  • HUMORFA01 antibody
  • mKIAA0051 antibody
  • p195 antibody
  • SAR1 antibody

Protein level used designations for IQGAP1

RasGAP-like with IQ motifs , ras GTPase-activating-like protein IQGAP1 , Cdc42-Rac1 effector protein

GENE ID SPECIES
8826 Homo sapiens
361598 Rattus norvegicus
29875 Mus musculus
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