IQGAP1 antibody (AA 256-285)

Catalog No. ABIN3031501

This Rabbit Polyclonal antibody specifically detects IQGAP1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IQGAP1 antibody (AA 256-285) (ABIN3031501)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IQGAP1 Antibody

Binding Specificity: AA 256-285

Purpose: IQGAP1 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 256-285 from the human protein was used as the immunogen for this IQGAP1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IQGAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IQGAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2