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The protein encoded by ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. Additionally we are shipping ICOS Kits (17) and ICOS Proteins (14) and many more products for this protein.
Showing 10 out of 123 products:
Mouse (Murine) Monoclonal ICOS Primary Antibody for BR, FACS - ABIN1176983
Buonfiglio, Bragardo, Redoglia, Vaschetto, Bottarel, Bonissoni, Bensi, Mezzatesta, Janeway Jr, Dianzani: The T cell activation molecule H4 and the CD28-like molecule ICOS are identical. in European journal of immunology 2001
Show all 9 Pubmed References
Mouse (Murine) Monoclonal ICOS Primary Antibody for FACS - ABIN2689139
Chambers: The expanding world of co-stimulation: the two-signal model revisited. in Trends in immunology 2001
Show all 8 Pubmed References
Human Monoclonal ICOS Primary Antibody for FACS - ABIN2689138
Dong, Nurieva: Regulation of immune and autoimmune responses by ICOS. in Journal of autoimmunity 2003
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Human Monoclonal ICOS Primary Antibody for Func, FACS - ABIN610262
Fusaro, Wang, Chellappan: Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis. in Oncogene 2002
Show all 2 Pubmed References
Human Monoclonal ICOS Primary Antibody for Func, FACS - ABIN610261
Saitoh, Pizzi, Wang: Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358. in The Journal of biological chemistry 2002
Show all 2 Pubmed References
Data show that inducible T cell co-stimulator (ICOS) deficient mice have a significant increase in the population of IL-17 (show IL17A Antibodies)-producing Vgamma2+ gammadelta T cells in the thymus, spleen, lymph nodes and skin and exhibit exacerbated sensitization responses to 2,4-dinitrofluorobenzene.
Our results indicate that ICOS regulates the ontogeny and homeostasis of B6.Sle1 lupus prone mouse T follicular helper (TFH) cells and influences the function of TFH cells during aberrant germinal center B cell responses
The expression of ICOSL (show ICOSLG Antibodies) in the cornea and the ICOS-mediated induction of Foxp3 (show FOXP3 Antibodies)+ CD4 (show CD4 Antibodies)+ regulatory T cells may contribute to successful corneal allograft survival.
this study reveals a previously unknown ICOS-TBK1 (show TBK1 Antibodies) signaling pathway that specifies the commitment of germinal center follicular helper T cells
IFNAR1 (show IFNAR1 Antibodies)-deficiency accelerated humoral immune responses and parasite control by boosting ICOS-signalling in two non-lethal murine models of malaria
Fecal levels of Crp1 (show CRIP1 Antibodies) were significantly decreased in mice with graft-versus-host disease and were correlated with intestinal flora diversity.
IL-10 (show IL10 Antibodies) production by CD4 (show CD4 Antibodies)(+) YFP(+) T cells is controlled systemically during malaria infection through IL-27 (show IL27 Antibodies) receptor signaling that is supported after CD4 (show CD4 Antibodies)(+) T cell priming by ICOS signaling.
these data suggest ICOS is not required for follicular Th cell induction during Plasmodium chabaudi chabaudi AS infection
the ICOS signaling has a regulatory effect on CD154 (show CD40LG Antibodies)/CD40 (show CD40 Antibodies) expressions, and may play an important role in the hepatic egg granuloma formation of schistosomiasis.
data identify a role of ICOS in innate immunity and indicate that not only cytokines, but also costimulatory pathways such as those involving ICOS, can contribute to regulate the ILC2 pool.
OX40 (show TNFRSF4 Antibodies) and ICOS (show CTLA4 Antibodies) act in a cooperative, nonredundant manner to maximize and prolong the T follicular helper cell response that is generated after acute virus infection
High ICOS (show CTLA4 Antibodies) expression is associated with colorectal neoplasms.
This is the first replication association study of rs4325730 upstream of ICOS (show CTLA4 Antibodies) with AIH in the Japanese population and rs4325730G is a risk allele.
the induction pathway of ICOS (show CTLA4 Antibodies)(+) Foxp3 (show FOXP3 Antibodies)(+) cells was analyzed
ratio of ICOS (show CTLA4 Antibodies)(+) /PD-1 (show PDCD1 Antibodies)(+) Tfh cells and the frequency of IL-21 (show IL17C Antibodies)(+) Tfh cells may be indicators for evaluating the idiopathic membranous nephropathy development
The ICOS (show CTLA4 Antibodies) and ICOSL (show ICOSLG Antibodies) SNPs examined do not have an apparent effect on the disease susceptibility and prognosis of autoimmune thyroid diseases.
Follicular helper T cells differentiation is a multistage process involving BCL6 (show BCL6 Antibodies) and other transcription factors, cytokines, and costimulation through ICOS (show CTLA4 Antibodies) and several other molecules. (Review)
findings show Tregs from inflamed lung of sarcoidosis patients characterized by ICOS (show CTLA4 Antibodies)(high) phenotype; high-level ICOS (show CTLA4 Antibodies) expression was restricted to Tregs from inflamed lung and was absent in blood Tregs of sarcoidosis patients and in lung and blood Tregs of healthy volunteers; potential implication of ICOS/ICOS (show CTLA4 Antibodies)-L (show ICOSLG Antibodies) immune-regulatory axis in in disease activity and resolution
findings indicated that circulating memory Tfh cells, especially CCR7 (show CCR7 Antibodies)+ICOS (show CTLA4 Antibodies)+ memory Tfh cells, may be associated with the relapse of MS and may serve as a new therapeutic target
Expression of mutant caspase-9 (show CASP9 Antibodies) correlated with a downregulation of BAFFR (show TNFRSF13C Antibodies) (B-cell-activating factor (show TNFSF13B Antibodies) belonging to the TNF (show TNF Antibodies) family (BAFF) receptor (show TNFRSF13C Antibodies)) in B cells and ICOS (inducible T-cell costimulator) in T cells.
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
inducible T-cell costimulator
, inducible T-cell co-stimulator
, CD28 and CTLA-4-like protein
, CD28-related protein 1
, activation-inducible lymphocyte immunomediatory molecule
, inducible costimulator