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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping Integrator Complex Subunit 6 Proteins (4) and Integrator Complex Subunit 6 Kits (1) and many more products for this protein.
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West Nile virus infection results in relocalization of DDX56 (show DDX56 Antibodies) from nucleoli to virus assembly sites on the endoplasmic reticululm (ER), an observation that is consistent with a role for DDX56 (show DDX56 Antibodies) in WNV virion assembly.
DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer.
Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p.
In response to the DNA damage response, INTS3 (show INTS3 Antibodies)-hSSB1 (show SSBP1 Antibodies)-INTS6 complex relocates to the DNA damage sites.
Findings suggest that EBV encoded miR (show MLXIP Antibodies)-BART3* miRNA targets DICE1 tumor suppressor to promote cellular growth and transformation in nasopharyngeal cancer(NPC (show NPC1 Antibodies)).
The helicase activity of DDX56 (show DDX56 Antibodies) is required for its role in assembly of infectious West Nile virus particles.
Coimmunoprecipitation confirmed that capsid protein binds to human DDX56 (show DDX56 Antibodies) in infected cells and that this interaction is required for assembly of infectious West Nile virus particles.
Somatic mutations were identified in three patients (3/56, 5%), and one novel polymorphism was identified in 3% of ESCC patients (4/136) and 3% of healthy individuals (6/232). We conclude that DICE1 mutations occur in ESCC but are infrequent.
DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I (show IGF1 Antibodies) signaling
DDX26 maps to7p12, a region of frequent chromosome amplifications in glioblastoma involving the EGFR (show EGFR Antibodies) gene.
Our results are consistent with a novel role for Ints6 (show DDX26B Antibodies) in restricting the vertebrate organizer to a dorsal domain in embryonic patterning.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
integrator complex subunit 6
, integrator complex subunit 6-like
, integrator complex subunit 6-B
, 61-kd nucleolar helicase
, ATP-dependent 61 kDa nucleolar RNA helicase
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
, DEAD box protein 21
, DEAD box protein 56
, DEAD-box RNA helicase
, nucleolar helicase of 61 kDa
, probable ATP-dependent RNA helicase DDX56
, putative nucleolar RNA helicase
, DEAD box protein
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
, RNA helicase HDB
, protein deleted in cancer 1