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Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. Additionally we are shipping IL17RA Antibodies (179) and IL17RA Kits (11) and many more products for this protein.
Showing 10 out of 31 products:
Human IL17RA Protein expressed in HEK-293 Cells - ABIN2181343
Puel, Cypowyj, Bustamante, Wright, Liu, Lim, Migaud, Israel, Chrabieh, Audry, Gumbleton, Toulon, Bodemer, El-Baghdadi, Whitters, Paradis, Brooks, Collins, Wolfman, Al-Muhsen, Galicchio, Abel, Picard et al.: Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. ... in Science (New York, N.Y.) 2011
Show all 2 references for ABIN2181343
Rat (Rattus) IL17RA Protein expressed in Human Cells - ABIN2009276
Schwandner, Yamaguchi, Cao: Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction. in The Journal of experimental medicine 2000
Show all 2 references for ABIN2009276
Cynomolgus IL17RA Protein expressed in Human Cells - ABIN2009892
Toy, Kugler, Wolfson, Vanden Bos, Gurgel, Derry, Tocker, Peschon: Cutting edge: interleukin 17 signals through a heteromeric receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 2 references for ABIN2009892
High IL-17RA expression is associated with Intrahepatic Cholangiocarcinoma.
Identified the IL17RA rs4819554 SNP as a risk factor for psoriasis.
IL-17 receptor A and adenosine deaminase 2 (show CECR1 Proteins) deficiency due to deletion mutations was found in siblings with chronic mucocutaneous candidiasis and chronic systemic inflammation.
In vitro, CSE stimulation significantly increased IL-17F and IL-17R in 16HBE (2.5%) and A549 (5%) while IL-17A and IL-17F in PBMC (10%). IL-17A and CSE stimulation, rather than CSE or rhIL-17A alone, increased proliferation in 16HBE and apoptosis in A549
The data indicate that the genetic variants of rs2275913 in IL-17A, rs763780 in IL-17F, and rs4819554 in IL-17RA may not play a role in the pathogenesis of preeclampsia in Chinese Han women.
IL17F (show IL17F Proteins) and IL17RA polymorphisms modulate susceptibility to cerebral malaria(CM) and provide evidence that IL-17F (show IL17F Proteins) protects against CM.
Increased expression of IL-17RA plays an important role in gastric cancer progression, migration and prognosis.
Both genetic variants of IL-17R (rs882643 and rs2241049) were associated with PGD (show PGD Proteins). This confirms a genetic predisposition toward PGD (show PGD Proteins) and suggests a role of IL-17 (show IL17A Proteins) in driving neutrophilia in PGD (show PGD Proteins).
The presence of IL7R (show IL7R Proteins) polymorphisms seems to be related to severe liver disease in HIV/hepatitis c virus coinfected patients.
expression of immunoreactivity for IL-17A (show IL17A Proteins), IL-17RA, IL-17E (show IL25 Proteins), and IL-17F (show IL17F Proteins) was significantly elevated in prostatic tissue from benign prostatic hyperplasia and prostate cancer compared with that in controls
IL-17RA in non hematopoietic cells regulates recruitment of neutrophils to the lung during the adaptive phase of the immune response.
Bronchial epithelial TLR2/IL17R signaling crosstalk is necessary for lung IL17 (show IL17A Proteins) homeostasis and is compromised by morphine.
IL-17 (show IL17A Proteins) signaling through IL-17RA is an important driver of lung inflammation and airway hyperresponsiveness.
results suggest that the p38alpha (show MAPK14 Proteins)-MKP-1 (show DUSP1 Proteins) signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.
There were no significant differences in clinical scores and numbers of infiltrating eosinophils among IL-25KO, TSLPR (show CRLF2 Proteins) KO, and wild-type mice.
IL-17RA signaling is critical for the development of renal pathology in autoimmune glomerulonephritis.IL-17 enhanced the production of proinflammatory cytokines and chemokines from tubular epithelial cells.
Il17ra appears to be a novel modulator of monocyte phenotype and possible therapeutic target in renal fibrosis
IL-17 (show IL17A Proteins) expression is higher in C57BL/6 versus BALB/c cornea after infection and that the latter group has more MerTK (show MERTK Proteins)+ cells.
It was concluded that TLR signaling can directly stimulate the expression of IL-17RA, but not IL-17RC (show IL17RC Proteins), in neuroglial cells, which functionally respond to IL-17A (show IL17A Proteins) by secreting chemokines, and accelerating CD4 (show CD4 Proteins) cell migration.
Absence of IL-17RA leads to a Th2-like phenotype characterized by IL-4 (show IL4 Proteins) production and suggests that IL-17RA signaling plays a critical role in the regulation of IL-4 (show IL4 Proteins) in collagen-induced arthritis and development of autoimmune inflammation of the joint.
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor\; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
IL-17 receptor A
, interleukin-17 receptor A