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Interleukin 33 Proteins (IL33)

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). Additionally we are shipping Interleukin 33 Antibodies (376) and Interleukin 33 Kits (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL33 90865 O95760
IL33 77125 Q8BVZ5
IL33 361749 Q66H70
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Top Interleukin 33 Proteins at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 5 to 8 Days
$267.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 16 Days
$822.80
Details
HOST_Escherichia coli (E. coli) Dog Un-conjugated 100 μg Log in to see 16 Days
$822.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$211.97
Details
HOST_Escherichia coli (E. coli) Human His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$638.00
Details

IL33 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) , , ,
,
Rat (Rattus)

Top referenced Interleukin 33 Proteins

  1. Human Interleukin 33 Primary Antibody for FACS - ABIN2666662 : Mildner, Storka, Lichtenauer, Mlitz, Ghannadan, Hoetzenecker, Nickl, Dome, Tschachler, Ankersmit: Primary sources and immunological prerequisites for sST2 secretion in humans. in Cardiovascular research 2010 (PubMed)
    Show all 6 references for ABIN2666662

  2. Human Interleukin 33 Primary Antibody for - ABIN2002684 : Cayrol, Girard: The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for ABIN2002684

  3. Human Interleukin 33 Primary Antibody for SDS - ABIN1344110 : Iikura, Suto, Kajiwara, Oboki, Ohno, Okayama, Saito, Galli, Nakae: IL-33 can promote survival, adhesion and cytokine production in human mast cells. in Laboratory investigation; a journal of technical methods and pathology 2007 (PubMed)
    Show all 3 references for ABIN1344110

  4. Dog (Canine) Interleukin 33 Primary Antibody for - ABIN2008834 : Schmitz, Owyang, Oldham, Song, Murphy, McClanahan, Zurawski, Moshrefi, Qin, Li, Gorman, Bazan, Kastelein: IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. in Immunity 2005 (PubMed)
    Show all 2 references for ABIN2008834

More Proteins for Interleukin 33 (IL33) Interaction Partners

Human Interleukin 33 (IL33) interaction partners

  1. Studies provide evidence that in response to tissue damage, IL-33 is released as a nuclear alarmin and triggers innate and adaptive immune responses by binding to its receptor ST2. Recent evidence from clinical and experimental animal studies indicates that the IL-33/ST2 axis is involved in the pathogenesis of chronic kidney disease, renal graft injury, systemic lupus nephritis, and acute kidney injury.[review]

  2. Studies indicate that interleukin (IL)-1beta (show IL1B Proteins), IL-1alpha, IL-33 and high-mobility group box 1 (HMGB1 (show HMGB1 Proteins)) enter the extracellular space through mechanisms collectively known as unconventional secretion.

  3. High IL-33 expression is associated with polycystic ovary syndrome.

  4. While serum TSLP (show TSLP Proteins) levels were unaffected by concomitant allergies and atopic comorbidities, serum levels of IL-31 (show IL31 Proteins), IL-33 and sST2 (show SSTR2 Proteins) were affected to a small extent. We found a positive correlation between TSLP (show TSLP Proteins), IL-31 (show IL31 Proteins) and IL-33, and an inverse relationship between IL-33 and sST2 (show SSTR2 Proteins)

  5. IL-33 showed significantly higher expression with increasing tumour grade in both malignant serous and mucinous tumours

  6. IL-33 expression is a novel prognostic marker for malignant salivary gland tumors

  7. The results of this study showed that the elevated IL-33 protein levels in glioma tissues compared to those in normal brain tissues.

  8. IL-33, which is a representative Th2 cytokine, affect as a crucial factor of skin barrier dysfunction by reducing FLG (show FGFR1 Proteins) expression in human keratinocytes.

  9. HMGB1 (show HMGB1 Proteins) and IL-33 could play a significant role in the atopic dermatitis pathophysiology due to negative regulation of structural proteins, stratum corneum formation and epidermal growth.

  10. this paper shows that IL-33 single nucleotide polymorphism may be a potential biomarker for susceptibility to systemic lupus erythematosus in a Chinese Han Population

Mouse (Murine) Interleukin 33 (IL33) interaction partners

  1. this study shows that IL-33 is likely a major factor in acute respiratory distress syndrome, and the release of HMGB1 (show HMGB1 Proteins) may be correlated with up-regulation of IL-33 expression

  2. the present study hypothesized that IL-33, as a 'master switch' of tissue repair that is secreted from dying or apoptotic cells, activated the IL-33-ST2-MyD88-TRAF6 pathway, amplified Th2-type responses and was involved in the pulmonary fibrosis process, via its receptor ST2, a stable marker of Th2 cells.

  3. Ras (G12V)-induced cyclin D1 (show CCND1 Proteins) protein synthesis was markedly suppressed by the knockdown of IL-33.

  4. anti-allergic effect of anti-IL-33 antibodies associated with suppression of immunoglobulin free light chain and nitric oxide synthase in a murine model of allergic rhinitis

  5. Data suggest that IL-33 and ST2 function as a developmental switch to license thermogenesis during the perinatal period.

  6. some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.

  7. Furthermore, IL-33 injection modulates the innate immune response by polarizing microglia/macrophages toward an antiinflammatory phenotype and reducing the expression of proinflammatory genes, including IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins), and NLRP3 (show NLRP3 Proteins), in the cortices of APP (show APP Proteins)/PS1 (show PSEN1 Proteins) mice. Collectively, our results demonstrate a potential therapeutic role for IL-33 in AD.

  8. absence of IL-33 has no negative consequences in normal bone homeostasis while high levels of circulating IL-33 contributes to pathological bone loss.

  9. pre-treatment with the ERK1/2 inhibitor U0126 or anti-IL-33 antibody significantly abolished the ovalbumin (show OVA Proteins)-induced airway remodeling, increased expressions of IL-33

  10. IL-33 promotes degranulation of bone marrow-derived mast cells and release of cytokines IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins) and TNF-alpha (show TNF Proteins).

Pig (Porcine) Interleukin 33 (IL33) interaction partners

  1. IL-33 may be a key molecule operating in eosinophil-mediated fibrosis in high-dose-per fraction irradiated skin.

Interleukin 33 (IL33) Protein Profile

Protein Summary

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). IL33 is a ligand for IL33R (IL1RL1\; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010

Gene names and symbols associated with Interleukin 33 Proteins (IL33)

  • interleukin 33 (IL33)
  • interleukin 33 (Il33)
  • interleukin 33-like (LOC100356081)
  • interleukin-33-like (LOC100518643)
  • 9230117N10Rik protein
  • C9orf26 protein
  • DVS27 protein
  • Il-33 protein
  • Il1f11 protein
  • IL33 protein
  • NF-HEV protein
  • NFEHEV protein
  • RGD1311155 protein
  • RP11-575C20.2 protein

Protein level used designations for Interleukin 33 Proteins (IL33)

interleukin 33 , IL-33 , interleukin-33 , DVS27-related protein , IL-1F11 , interleukin-1 family member 11 , nuclear factor for high endothelial venules , nuclear factor from high endothelial venules

GENE ID SPECIES
737537 Pan troglodytes
100171950 Pongo abelii
90865 Homo sapiens
77125 Mus musculus
361749 Rattus norvegicus
100715993 Cavia porcellus
403810 Canis lupus familiaris
507054 Bos taurus
101116705 Ovis aries
100356081 Oryctolagus cuniculus
100518643 Sus scrofa
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