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anti-LIM Domain Kinase 2 (LIMK2) Antibodies

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. Additionally we are shipping LIMK2 Proteins (9) and LIMK2 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LIMK2 3985 P53671
LIMK2 29524 P53670
LIMK2 16886 O54785
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Top anti-LIMK2 Antibodies at antibodies-online.com

Showing 10 out of 123 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using LIMK2 (Phospho-Ser283) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using LIMK2 (Phospho-Thr505) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using LIMK2 (Phospho-Thr505) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HepG2/HuvEc cells, using LIMK2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using LIMK2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with UV, using LIMK2 (Ab-505) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC, WB   100 μL Log in to see 2 to 3 Days
$306.90
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using LIM kinase 2, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2000. WB Image Sample (30μg whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

LIMK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LIMK2 Antibodies

  1. Human Polyclonal LIMK2 Primary Antibody for IF, IHC - ABIN362110 : Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN362110

  2. Human Polyclonal LIMK2 Primary Antibody for IF, IHC (p) - ABIN196832 : Edwards, Sanders, Bokoch, Gill: Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. in Nature cell biology 1999 (PubMed)
    Show all 2 references for ABIN196832

  3. Human Polyclonal LIMK2 Primary Antibody for IHC, ELISA - ABIN1532018 : Dunham, Shimizu, Roe, Chissoe, Hunt, Collins, Bruskiewich, Beare, Clamp, Smink, Ainscough, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beasley, Bird, Blakey, Bridgeman, Buck, Burgess, Burrill et al.: The DNA sequence of human chromosome 22. ... in Nature 1999 (PubMed)

More Antibodies against LIMK2 Interaction Partners

Human LIM Domain Kinase 2 (LIMK2) interaction partners

  1. This study showed that LIMK2 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  2. Actin remodelling factor LIMK2 is a key player in the ciliogenesis control network in which YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) and directional vesicle trafficking are integral components.

  3. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 (show LIMK1 Antibodies) and LIMK2 expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  4. results highlight the exciting possibility of combining specific LIMK2 inhibitors with anticancer drugs in the treatment of multi-drug resistant cancers

  5. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice and in human colorectal cancer cell lines and tumours. LIMK2 expression progressively decreased with advancing stage of colorectal cancer.

  6. Overexpression of LIMK2 is associated with breast cancer growth and invasiveness.

  7. Nf1/LIMK2 interaction and inhibition allows to directly connect neurofibromatosis type I to actin cytoskeleton remodeling.

  8. A novel activity of Rho in promoting a complex between fascin-1 and LIMK1/2 that modulates the interaction of fascin-1 with actin, was identified.

  9. LIMK2 is a key regulator that acts through different substrates to provide functional links between the actin cytoskeleton and spindle dynamics.

  10. LIMK2 positively regulates the level of Aurora A (show AURKA Antibodies), thereby engaging in a positive-feedback loop, promoting Aurora-A (show AURKA Antibodies)-mediated oncogenic pathways.

Mouse (Murine) LIM Domain Kinase 2 (LIMK2) interaction partners

  1. These data suggest that osteoblasts can increase their mechanosensitivity under continuous mechanical stimulation by reducing the actin stress fiber formation through inhibiting the LIMK2 expression.

  2. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice.

  3. LIMK2 activity is required for keratinocyte migration in the developing eyelid.

  4. Using RNAi against LIMK2 to inhibit the cytoskeleton reorganization can promote the expression of c-fos gene and thus enhance the mechanosensitivity of c-fos gene in osteoblasts.

  5. Results suggest that constitutive activation of the Rho-ROCK-LIM (show PDLIM5 Antibodies) kinase pathway by extracellular production of lysophosphatidic acid by the action of autotaxin (show ENPP2 Antibodies) is required to maintain the large size of lysosomes in visceral endoderm cells.

  6. LIMK-1 (show LIMK1 Antibodies)/2 double knockout mice were more severely impaired in both ADF/cofilin (show CFL1 Antibodies) phosphorylation and excitatory synaptic function in the CA1 (show CA1 Antibodies) region of the hippocampus.

  7. a novel pathway emanating from the TGF-beta type I receptor (show TGFBR1 Antibodies) and leading to regulation of actin assembly, via the kinase LIMK2.

LIMK2 Antigen Profile

Protein Summary

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMK2

  • LIM domain kinase 2 (limk2) antibody
  • LIM domain kinase 2 (LIMK2) antibody
  • LIM domain kinase 2 (LOC100223808) antibody
  • similar to LIM domain kinase 2 (LIMK2) antibody
  • LIM domain kinase 2 (Limk2) antibody
  • LIM motif-containing protein kinase 2 (Limk2) antibody
  • 9430059K01 antibody
  • A930024P04Rik antibody
  • C85310 antibody
  • LIMK antibody
  • LIMK2 antibody
  • Limk2a antibody
  • Limk2b antibody
  • Link2 antibody
  • wu:fa97c09 antibody
  • wu:fk73e11 antibody
  • xlimk2 antibody
  • zgc:91990 antibody

Protein level used designations for LIMK2

XLIM-Kinases2 , LIM domain kinase 2 , LIM domain kinase 2-like , LIM motif-containing protein kinase 2 , LIMK-2 , LIM kinase 2 , LIM-containing protein kinase 2a , LIM-containing protein kinase 2t , Limk2t-1 and Limk2t-2

GENE ID SPECIES
398298 Xenopus laevis
436924 Danio rerio
486363 Canis lupus familiaris
100058419 Equus caballus
100216249 Xenopus (Silurana) tropicalis
100223808 Taeniopygia guttata
100396965 Callithrix jacchus
100586214 Nomascus leucogenys
458970 Pan troglodytes
716614 Macaca mulatta
100478557 Ailuropoda melanoleuca
3985 Homo sapiens
29524 Rattus norvegicus
513539 Bos taurus
396010 Gallus gallus
16886 Mus musculus
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