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anti-Lumican (LUM) Antibodies

LUM encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. Additionally we are shipping Lumican Kits (33) and Lumican Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LUM 4060 P51884
LUM 17022 P51885
LUM 81682 P51886
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Top anti-Lumican Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of LUM antibody (Center) (ABIN391882) in A375 cell line lysates (35 µg/lane). LUM (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with LUM Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of LUM Antibody (N-term) (ABIN391881) in mouse bladder tissue lysates (35 µg/lane). LUM (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with LUM Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LUM Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart WB Suggested Anti-LUM  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC (p), ELISA, WB Anti- Lumican Picoband antibody, IHC(P) IHC(P): Mouse Brain Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, WB Sample Type: mouse cornea (cystinosin Ko)Blue: DAPIRed: LumPrimary Dilution: 1:250Image Submitted By: Geraint ParfittGavin Herbert Eye Institute . 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western Blot analysis of LUM expression in transfected 293T cell line by LUM MaxPab polyclonal antibody.Lane 1: LUM transfected lysate(38.40 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
$269.50
Details

LUM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lumican Antibodies

  1. Human Polyclonal LUM Primary Antibody for WB - ABIN517580 : Gasimli, Stansfield, Nairn, Liu, Paluh, Yang, Dordick, Moremen, Linhardt: Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells. in Glycoconjugate journal 2013 (PubMed)
    Show all 2 references for ABIN517580

  2. Human Polyclonal LUM Primary Antibody for FACS, IHC (p) - ABIN391882 : Wang, Li, Xiao, Jia, Jiao, Guo, Zhang: High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes. in Investigative ophthalmology & visual science 2009 (PubMed)

More Antibodies against Lumican Interaction Partners

Horse (Equine) Lumican (LUM) interaction partners

  1. temporal expression of LUM mRNA during dermal wound repair in the horse

Zebrafish Lumican (LUM) interaction partners

  1. the role of lumican in the development of axial myopia

Human Lumican (LUM) interaction partners

  1. fibroblasts stimulated with the fibrocyte-secreted inflammatory signal tumor necrosis factor-alpha (show TNF Antibodies) secrete the small leucine-rich proteoglycan (show Vcan Antibodies) lumican.

  2. This meta-analysis suggests that LUM polymorphisms are associated with the risk of high myopia.

  3. The results suggest that regions within LUM is associated with ACL (show ACLY Antibodies) injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties.

  4. meta-analysis, including 1,545 subjects from 5 studies, indicated that Chinese lumican rs3759223 C allele carriers had a decreased risk of high myopia in comparison to T allele carriers

  5. These findings suggest that lumican is a potent differential diagnostic marker that distinguishes hidroacanthoma simplex from clonal-type seborrheic keratosis.

  6. Lumican, decorin (show DCN Antibodies) and dermatopontin (show DPT Antibodies) are differentially expressed and may serve as biomarkers for metastatic and recurrent Giant cell tumor of bone

  7. Lumican binds ALK5 (show TGFBR1 Antibodies) to promote epithelium wound healing

  8. Lack of Lumican expression is associated with recurrence in colon cancer.

  9. These findings suggest that lumican plays an important role in the pathogenesis of Bowen disease and actinic keratosis

  10. lumican may be involved in cell growth and invasion through the regulation of 24 proteins expressed in pancreatic ductal adenocarcinoma.

Mouse (Murine) Lumican (LUM) interaction partners

  1. LUM may coordinate multiple factors of collagen assembly in the murine heart.

  2. Lumican and biglycan (show BGN Antibodies) influence corneal keratocyte lamellipodia organization and are critical in the regulation of stromal collagen fibrillogenesis.

  3. Alterations in glycosylated lumican core protein might be implicated in myocardial remodeling and reverse remodeling, with a potential important role for CS/DS GAG chain-synthesizing enzymes.

  4. pro-inflammatory cytokine TNF-alpha (show TNF Antibodies) was comparably low 24 hours after infection, but significantly higher in the Lum(-/-) compared to Lum(+/-) infected corneas by 2-5 days after infection

  5. lumican present in the reactive stroma surrounding prostate primary tumors plays a restrictive role on cancer progression

  6. To investigate the functional role of lumican in hepatic fibrosis, lumican null (Null) and wild-type (WT) littermates were administered carbon tetrachloride intra-peritoneally. Hepatic fibrosis was greatly reduced in null animals.

  7. lumican has a major protective role in gram-negative bacterial infections, a novel function for small leucine-rich repeat proteoglycans.

  8. deficiency combined with fibromodulin (show FMOD Antibodies) deficiency manifest several clinical features or Ehlers-Danlos syndrome

  9. The results indicate that the cysteine-rich domain of lumican is important in collagen fibrillogenesis and stromal matrix assembly

  10. lumican has a novel regulatory role in keratocan (show KERA Antibodies) expression at the transcriptional level

Cow (Bovine) Lumican (LUM) interaction partners

  1. These results suggest that lumican plays a pivotal role in the development of tissue engineered cartilage and that regulation of this protein may be important for the production of high-quality implants.

Rabbit Lumican (LUM) interaction partners

  1. FGF-2 (show FGF2 Antibodies)- and TGF-beta1 (show TGFB1 Antibodies)-activation of JNK (show MAPK8 Antibodies) signaling pathway may be partly responsible for the downregulation of keratocan (show KERA Antibodies) and lumican expression in activated corneal keratocytes observed during corneal stromal wound healing.

Lumican (LUM) Antigen Profile

Protein Summary

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Gene names and symbols associated with anti-Lumican (LUM) Antibodies

  • lumican (LUM) antibody
  • lumican (lum) antibody
  • lumican (CpipJ_CPIJ010209) antibody
  • lumican (Lum) antibody
  • DKFZp468L1116 antibody
  • Ldc antibody
  • MGC64527 antibody
  • SLRR2D antibody
  • zgc:86661 antibody

Protein level used designations for anti-Lumican (LUM) Antibodies

lumican , zlum , Keratan sulfate proteoglycan lumican , KSPG lumican , keratan sulfate proteoglycan lumican , lumican proteoglycan , KSPG , corneal keratan sulfate proteoglycan 37B core protein , keratan sulfate proteoglycan

GENE ID SPECIES
100009681 Equus caballus
379493 Xenopus laevis
415149 Danio rerio
452119 Pan troglodytes
482599 Canis lupus familiaris
496415 Xenopus (Silurana) tropicalis
709830 Macaca mulatta
6043170 Culex quinquefasciatus
100126729 Papio anubis
100171487 Pongo abelii
100195033 Salmo salar
100595797 Nomascus leucogenys
4060 Homo sapiens
17022 Mus musculus
81682 Rattus norvegicus
100152607 Sus scrofa
280847 Bos taurus
417891 Gallus gallus
100008665 Oryctolagus cuniculus
100732503 Cavia porcellus
Selected quality suppliers for anti-Lumican (LUM) Antibodies
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