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anti-MCF.2 Cell Line Derived Transforming Sequence (MCF2) Antibodies

The oncogenic protein encoded by MCF2 is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Additionally we are shipping MCF2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MCF2 4168 P10911
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Top anti-MCF2 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of K562 cells using MCF2 Antibody (C-term) Cat.-No AP52634PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with MCF2 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB MCF2 Antibody (C-term) (ABIN656494) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Biotin FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

MCF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Top referenced anti-MCF2 Antibodies

  1. Human Polyclonal MCF2 Primary Antibody for EIA, FACS - ABIN953349 : Rojas, Yohe, Gershburg, Kawano, Kozasa, Sondek: Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for ABIN953349

More Antibodies against MCF2 Interaction Partners

Human MCF.2 Cell Line Derived Transforming Sequence (MCF2) interaction partners

  1. Results support a role for Dbl oncogene (show RAB1A Antibodies) in mammary epithelial cell differentiation and transformation and suggest the relevance of GEF (show SLC2A4RG Antibodies) deregulation in tumor onset and progression.

  2. Phosphoinositide 3-kinase C2beta regulates RhoA (show RHOA Antibodies) and the actin cytoskeleton through an interaction with Dbl

  3. Dbl is regulated by hamartin (show TSC1 Antibodies) through association with ezrin (show EZR Antibodies).

  4. proto-oncogene dbl is not a major target for sporadic testicular germ cell tumors

  5. data describe 4 splicing variants of the human DBL (MCF-2) proto-oncogene (show RAB1A Antibodies) that show different tissue distributions and guanine nucleotide exchange factor (show RASGRF1 Antibodies) specificities

  6. provides fundamental data on the structure of Mcf-2, which regulates a variety of cellular signaling pathways

  7. These data suggest a mechanism whereby precise spatial guanine nucleotide exchange of Cdc42 (show CDC42 Antibodies) by Dbl is dependent on functional ERM (show ETV5 Antibodies) proteins and is important for directional cell migration.

  8. Galphaq (show GNAQ Antibodies) directly activates p63RhoGEF and Trio (show TRIO Antibodies) via a conserved extension of the Dbl homology-associated pleckstrin (show PLEK Antibodies) homology domain

  9. Nm23-H1 (show NME1 Antibodies) can negatively regulate cell migration and tumor metastasis by modulating the activity of Cdc42 (show CDC42 Antibodies) and possibly other Rho family members through interaction with Dbl-1

MCF2 Antigen Profile

Protein Summary

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

Gene names and symbols associated with MCF2

  • MCF.2 cell line derived transforming sequence (MCF2) antibody
  • ARHGEF21 antibody
  • DBL antibody

Protein level used designations for MCF2

Oncogene MCF2 (oncogene DBL) , proto-oncogene DBL , proto-oncogene MCF-2

GENE ID SPECIES
4168 Homo sapiens
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