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anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) Antibodies

HLA-DMB belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA-DMB Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DMB 3109 P28068
Anti-Rat HLA-DMB HLA-DMB 294273  
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Top anti-HLA-DMB Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.62 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-HLA DMB antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: HLA-DMB  Sample Tissue: Human Placenta  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB HLA-DMB Antibody (Center)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HLA-DMB antibody detected the HLA-DMB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB HLA-DMB Antibody (Center)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HLA-DMB antibody detected the HLA-DMB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Western Blot analysis of HLA-DMB expression in transfected 293T cell line by HLA-DMB polyclonal antibody. A:Non-transfected lysate. B:HLA-DMB transfected lysate. 12% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using HLA-DMB, antibody at 1:250 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated IF, IP, ELISA, WB Western Blot analysis of HLA-DMB expression in transfected 293T cell line by HLA-DMB monoclonal antibody (M06), clone 5G11.Lane 1: HLA-DMB transfected lysate(28.9 KDa).Lane 2: Non-transfected lysate. Immunoprecipitation of HLA-DMB transfected lysate using anti-HLA-DMB monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with HLA-DMB MaxPab rabbit polyclonal antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IP, ELISA, WB Western Blot analysis of HLA-DMB expression in transfected 293T cell line by HLA-DMB monoclonal antibody (M07), clone 7D11.Lane 1: HLA-DMB transfected lysate(28.9 KDa).Lane 2: Non-transfected lysate. Immunoprecipitation of HLA-DMB transfected lysate using anti-HLA-DMB monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with HLA-DMB MaxPab rabbit polyclonal antibody. 100 μg Log in to see 9 Days
$430.00
Details

HLA-DMB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Top referenced anti-HLA-DMB Antibodies

  1. Human Monoclonal HLA-DMB Primary Antibody for ELISA, WB - ABIN561269 : Callahan, Nagymanyoki, Bonome, Johnson, Litkouhi, Sullivan, Hirsch, Matulonis, Liu, Birrer, Berkowitz, Mok: Increased HLA-DMB expression in the tumor epithelium is associated with increased CTL infiltration and improved prognosis in advanced-stage serous ovarian cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 2 references for ABIN561269

More Antibodies against HLA-DMB Interaction Partners

Human Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) interaction partners

  1. Data suggest that antigen processing by MHC class II HLA-DMB antigen is a target pathway in the pathogenesis of HIV-related Kaposi's sarcoma.

  2. DMA (show HLA-DMA Antibodies)*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans

  3. Overexpression of HLA-DM at the plasma membrane of dendritic cells improves quantitatively, but also qualitatively, the presentation of CD4 (show CD4 Antibodies)-expressing T cell epitopes in cellular vaccine therapies for cancer.

  4. HLA-DM mediates a noncooperative release of prebound influenza virus hemagglutinin (show HA Antibodies) peptides from wild-type HLA-DR1 (show DR1 Antibodies) by destabilizing the beta81 hydrogen (H-)bond, since a similar phenomenon is observed when this H-bond is absent.

  5. HLA DMA (show HLA-DMA Antibodies) and DMB show no association with rheumatoid arthritis in US Caucasians.

  6. HLA-DMB may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.

  7. glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta (show GPHb5 Antibodies), while DMbeta (show GPHb5 Antibodies) forms disulfide-linked homodimers without DMalpha

  8. findings suggest HLA-DM expression in antigen presenting cells controls class II-mediated type II collagen (show COL2A1 Antibodies)(261-273) peptide/epitope presentation & regulates CD4 (show CD4 Antibodies)+ T cell responses to this self epitope, potentially influencing CII-dependent autoimmunity

  9. Tumor cell expression of HLA-DMB is associated with increased numbers of tumor-infiltrating CD8 (show CD8A Antibodies) T lymphocytes and both are associated with improved survival in advanced-stage serous ovarian cancer.

  10. No individual component of conserved HLA-DM hydrogen bond network demonstrates an essential role in the DM catalytic mechanism. Catalytic potency of HLA-DM with each beta-chain mutant was equal to or greater than that observed with wild-type HLA-DR1 (show DR1 Antibodies).

HLA-DMB Antigen Profile

Protein Summary

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Gene names and symbols associated with HLA-DMB

  • major histocompatibility complex, class II, DM beta (HLA-DMB) antibody
  • RT1 class II, locus DMb (RT1-DMb) antibody
  • major histocompatibility complex, class II, DM beta (PATR-DMB) antibody
  • D6S221E antibody
  • MHC-DMB antibody
  • RING7 antibody
  • RT1.DMb antibody
  • RT1.Mb antibody

Protein level used designations for HLA-DMB

HLA class II histocompatibility antigen, DM beta chain , MHC class II HLA-DMB , MHC class II antigen DMB , MHC class II antigen HLA-DM beta chain , class II histocompatibility antigen, M beta chain , really interesting new gene 7 protein , MHC class II-like beta chain , RT1 class II, DM beta , major histocompatibility complex, class II, DM beta

GENE ID SPECIES
3109 Homo sapiens
294273 Rattus norvegicus
449592 Pan troglodytes
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