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anti-Matrix Metalloproteinase 2 (MMP2) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP2 Kits (117) and MMP2 Proteins (51) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP2 81686 P33436
MMP2 17390 P33434
MMP2 4313 P08253
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Top anti-MMP2 Antibodies at

Showing 10 out of 398 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 10 to 12 Days
Human Mouse Un-conjugated Func, IHC (p), WB 0.1 mg Log in to see 10 to 12 Days
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB Western blot analysis of MMP2 (arrow) using rabbit polyclonal MMP2 Antibody (Center) (ABIN657616). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MMP2 gene. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT-29 cells, using MMP-2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated ICC, IHC (fro), IF, IHC (p), IP, IHC, ELISA, WB Detection of MMP-2 staining in formalin-fixed paraffin-embedded human ovary tissue using ABIN152258.  Primary antibody was used at 2.5 ug/ml with the avidin-biotin-peroxidase detection method. Western Blot: MMP2 Antibody (8B4) [ABIN152258] - Western blot analysis of MMP2 expression in ProMMP2 (Lane 1), Active MMP2 (Lane 2) and human pressure ulcer biopsy (Lane 3). 0.1 mL Log in to see 5 to 7 Days
Chicken Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), WB Detection of MMP2 in a paraffin-embedded human neurofibroma section.  Stained using ABIN152329. Detection of MMP2 in a frozen injured rat nerve tissue section.  Stained using ABIN152329. 0.1 mL Log in to see 5 to 7 Days
Guinea Pig Mouse Un-conjugated ELISA, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB 0.1 mL Log in to see 5 to 7 Days
Human Mouse Un-conjugated ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using MMP2 mouse mAb against A431 (1) cell lysate. 0.1 mg Log in to see 3 to 4 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-MMP-2 Polyclonal Antibody (ABIN668286), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days

MMP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MMP2 Antibodies

  1. Chicken Polyclonal MMP2 Primary Antibody for ICC, IF - ABIN152329 : Krekoski, Neubauer, Graham, Muir: Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 (PubMed)
    Show all 37 references for ABIN152329

  2. Human Monoclonal MMP2 Primary Antibody for ICC, IHC (fro) - ABIN152258 : Locke, Royce, Wainewright, Samuel, Tang: Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease. in American journal of respiratory cell and molecular biology 2007 (PubMed)
    Show all 12 references for ABIN152258

  3. Human Polyclonal MMP2 Primary Antibody for IF (p), IHC (p) - ABIN668286 : Wu, Fan, Zhang, Ning, Zeng, Zhou, Li, Chen, Zhang, Wang, Hsieh, He: PI3K/Akt to GSK3?/?-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription. in Cellular signalling 2012 (PubMed)
    Show all 10 references for ABIN668286

  4. Human Monoclonal MMP2 Primary Antibody for Func, IHC (p) - ABIN180364 : Soini, Hurskainen, Höyhtyä, Oikarinen, Autio-Harmainen: 72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994 (PubMed)
    Show all 7 references for ABIN180364

  5. Human Monoclonal MMP2 Primary Antibody for IHC (p), IP - ABIN180365 : Autio-Harmainen, Karttunen, Hurskainen, Höyhtyä, Kauppila, Tryggvason: Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors. in Laboratory investigation, a journal of technical methods and pathology 1993 (PubMed)
    Show all 7 references for ABIN180365

  6. Guinea Pig Monoclonal MMP2 Primary Antibody for ELISA, ICC - ABIN152257 : Rork, Hadzimichalis, Kappil, Merrill: Acetaminophen attenuates peroxynitrite-activated matrix metalloproteinase-2-mediated troponin I cleavage in the isolated guinea pig myocardium. in Journal of molecular and cellular cardiology 2006 (PubMed)
    Show all 3 references for ABIN152257

  7. Human Polyclonal MMP2 Primary Antibody for WB - ABIN657616 : Shi, Shang, Pan, Wang, Jiang, Hao, Zhang, Cai, Xu, Zhan, Wang: Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 references for ABIN657616

  8. Human Monoclonal MMP2 Primary Antibody for ELISA, WB - ABIN1098146 : Langers, Verspaget, Hawinkels, Kubben, van Duijn, van der Reijden, Hardwick, Hommes, Sier: MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients. in British journal of cancer 2012 (PubMed)
    Show all 2 references for ABIN1098146

  9. Human Polyclonal MMP2 Primary Antibody for ELISA, WB - ABIN1533350 : Matsumoto, Niimi, Kohyama: Characterization of fibrosis-promoting factors and siRNA-mediated therapies in C-protein-induced experimental autoimmune myocarditis. in Cellular immunology 2012 (PubMed)

  10. Cow (Bovine) Polyclonal MMP2 Primary Antibody for IHC, WB - ABIN2792308 : Collier, Wilhelm, Eisen, Marmer, Grant, Seltzer, Kronberger, He, Bauer, Goldberg: H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. in The Journal of biological chemistry 1988 (PubMed)

More Antibodies against MMP2 Interaction Partners

Horse (Equine) Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. study demonstrated that matrix metalloproteinase 1 (show MMP1 Antibodies) and 2 might be fundamental for events related to equine tissue remodeling, which occurs during follicular development

Fruit Fly (Drosophila melanogaster) Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. We also show that follicular OA-Oamb signaling induces Mmp2 enzymatic activation but not Mmp2 protein expression, likely via intracellular Ca2 (show CA2 Antibodies)+ as the second messenger.

  2. Finally, matrix metalloproteinase 2 (Mmp2), a type of protease thought to facilitate mammalian ovulation, is expressed in mature follicle and corpus luteum cells.

  3. As a Wnt (show WNT4 Antibodies) signaling antagonist, MMP2 cleaves the glypican (show GPC1 Antibodies), reducing the ability of Dlp (show DMD Antibodies) to interact with the Wnt (show WNT4 Antibodies) ligand and promote its distribution.

  4. Matrix metalloproteinase 2 is required for fat-body remodeling in Drosophila

  5. Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila.

  6. Dendrite reshaping of adult Drosophila sensory neurons requires matrix metalloproteinase MMP2-mediated modification of the basement membranes

  7. Mmp2 expression in the developing air sac (show ADCY10 Antibodies) is controlled by the Drosophila FGF homolog Branchless and then participates in a negative feedback and lateral inhibition mechanism that defines the precise pattern of FGF signaling.

  8. findings demonstrate a critical role for Mmp2 in tubulogenesis post-induction, and implicate Mmp2 in regulating dynamic and essential changes to the extracellular matrix

Zebrafish Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. Dexamethasone and hydrocortisone alter expression and activity of MMP-2 and MMP-9 (show MMP9 Antibodies) in the embryonic zebrafish.

Mouse (Murine) Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. activation of astrocyte MMP2/JNK1 (show MAPK8 Antibodies)/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model

  2. Ceramide 1-phosphate -stimulated macrophage migration is a receptor mediated effect, and point to MMP-2 and -9 as possible therapeutic targets to control inflammation.

  3. MMP-2 potentiates shear-induced platelet activation by enhancing thrombus formation

  4. Identify novel MMP-2/cardiac sPLA2 (show PLA2G2A Antibodies) pathway that endows the heart with important endocrine functions, including regulation of inflammation and lipid metabolism in the liver.

  5. 129/SvEv mice are more susceptible to abdominal aortic aneurysms compared to C57Bl/6 mice and suggest roles for MMP2/9.

  6. Report cross-talk between macrophages, smooth muscle cells, and endothelial cells in response to cigarette smoke alters MMP2/9 levels.

  7. MMP-2 silenced hypoxic fibroblasts under hyperglycemic conditions have impaired angiogenic potential. Collagen I/IV secretion is decreased and cell migration is prevented.

  8. N-terminal truncated isoform-MMP-2, but not full-length-MMP-2, is the major isoform of MMP-2 involved in skeletal muscle Ischemia-reperfusion injury.

  9. These data indicate that oxygen-glucose deprivation-triggered Cav-1 (show CAV1 Antibodies) S-nitrosylation interacts with tPA (show PLAT Antibodies)-induced ERK (show EPHB2 Antibodies) activation to augment MMP2 and 9 secretion and subsequent extracellular matrix degradation.

  10. Type IV collagenases, MMP-2 and MMP-9 (show MMP9 Antibodies), play important roles in hair cycle, and this could be mediated by induced expression of VEGF (show VEGFA Antibodies), IGF-1 (show IGF1 Antibodies), and TGF-beta (show TGFB1 Antibodies).

Human Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. Increased levels of MMP-2 is associated with hypertension.

  2. Early post-transplant concentration of MMP-2 is a marker of proteinuria in early and long-term post-transplant periods.

  3. The regulatory connection between HIF-2alpha (show EPAS1 Antibodies) and VEGFR-1 (show FLT1 Antibodies), VEGFR-2 (show KDR Antibodies) and MMP2.

  4. Presence of MMP-2 (-1306 C/T) might be associated the risk of MetS (show ETV3 Antibodies).

  5. Furthermore, mir106a transfection resulted in decreased expression of MMP-2 and diminished binding activity of transcription factor Ets (show ETV7 Antibodies)-1 (show ETS1 Antibodies) in EJ cells.

  6. ectopic expression of miR-17 in ovarian cancer cells resulted in repressed ILK (show ILK Antibodies) phosphorylation as well as decreased production of active matrix metalloproteinase-2 (MMP-2). Our results indicated that miR-17 hampered ovarian cancer peritoneal propagation by targeting integrin a5 and b1.

  7. Results show that the expressions of MMP-2 and MMP-9 (show MMP9 Antibodies) mRNA significantly higher in basal cell carcinoma (BCC) of skin cancer patients. The expression of mRNA for MMP-9 (show MMP9 Antibodies) but not for MMP-2 was significantly higher in infiltrative BCCs than in the nodular BCCs.

  8. RUNX3 overexpression inhibited CRC cell migration and invasion resulting from the upregulation of matrix metalloproteinase-2 (MMP-2) and MMP-9 expression. the knockdown of RUNX3 reduced the inhibition of migration and invasion of CRC cells. Finally, we found that restoration of RUNX3 decreased vascular endothelial growth factor (VEGF) secretion and suppressed endothelial cell growth and tube formation

  9. Lunasin suppresses the metastasis of breast cancer cells through integrin-mediated FAK (show PTK2 Antibodies)/Akt (show AKT1 Antibodies)/ERK (show EPHB2 Antibodies) and NF-kappaB (show NFKB1 Antibodies) signaling pathways followed by downregulation of the activity and expression of MMP-2/-9.

  10. This study identified that combination of nadroparin and irradiation had a strong synergistic antitumor effect in a dose- and time-related manner in vitro, which was reflected in the inhibition of cell viability, invasion and metastasis, promotion of apoptosis, inhibited secretion level of TGF-beta1 (show TGFB1 Antibodies) and downregulation of CD147, MMP-2 and survivin (show BIRC5 Antibodies) expression.

Cow (Bovine) Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. The expression patterns of MMP1 (show MMP1 Antibodies), MMP2, and MMP8 (show MMP8 Antibodies) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1 (show MMP1 Antibodies), MMP2, and MMP8 (show MMP8 Antibodies) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1 (show MMP1 Antibodies), MMP2, and MMP8 (show MMP8 Antibodies) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  2. The results showed that a decrease in MMP-1 (show MMP1 Antibodies) and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  3. Activation of cytosolic MMP-9 (show MMP9 Antibodies) and MMP-2 was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.

  4. Data indicate the involvement of PKC-alpha (show PKCa Antibodies) in proMMP-2 activation and inhibition of TIMP-2 (show TIMP2 Antibodies) expression by NF-kappaB (show NFKB1 Antibodies)-MT1-MMP (show MMP14 Antibodies)-dependent and -independent pathway.

  5. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14 (show MMP14 Antibodies)) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells.

  6. Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase (show CA-P60A Antibodies) activity, but the pretreatment with TIMP-2 (show TIMP2 Antibodies) inhibits the increase in the enzyme activity

  7. A differential pattern of matrix metalloproteinase-2 and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.

  8. MMP-14 (show MMP14 Antibodies), MMP-2 and TIMP-2 (show TIMP2 Antibodies) are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.

  9. Results describe distinct changes in expression of MMP2, MMP14 (show MMP14 Antibodies), and the metallopeptidase (show ECEL1 Antibodies) inhibitor TIMP2 (show TIMP2 Antibodies) between different phases of the estrous cycle indicating an endocrine regulation.

  10. EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 and MMP-14 (show MMP14 Antibodies) suggesting a role in adhesion and fusion of embryo to luminal epithelium.

Pig (Porcine) Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (show MMP9 Antibodies), TIMP1 (show TIMP1 Antibodies), and NGAL (show LCN2 Antibodies) (also MMP2 in 220 kDa complex) without proteolytic activity.

  2. Data demonstrate for the first time that MMP2 and MMP9 (show MMP9 Antibodies) are expressed in swine ovarian follicle both in theca and granulosa layers.

  3. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (show MMP9 Antibodies) and MMP-2, caspase-3 (show CASP3 Antibodies) and BDNF (show BDNF Antibodies)

  4. MMP-2 may play an important role in regulating MLC1 turnover in the heart under normal physiological conditions

  5. Oxygen for newborn resuscitation increases MMP-2/-9 activity resulting in tissue damage and influencing remodeling processes.

  6. PI3K-dependent regulation of MT1-MMP (show MMP14 Antibodies) protein synthesis and subsequent activation of latent MMP-2 as critical events in neointimal hyperplasia after vascular injury.

  7. MMP-2 processes dental sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis

  8. contribution of MMPs to the inflammatory breakdown of the blood-CSF (show CSF2 Antibodies) barrier in vitro

  9. The levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 (show MMP9 Antibodies) in the corpus luteum of swine during luteolysis are reported.

  10. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA Antibodies), pro-MMP-9 (show MMP9 Antibodies), MMP-2, VEGFR-1 (show FLT1 Antibodies), VEGFR-2 (show KDR Antibodies), and TIMP-1 (show TIMP1 Antibodies), which may contribute to the development of venous stenosis.

Rabbit Matrix Metalloproteinase 2 (MMP2) interaction partners

  1. Inflammatory factors such as TNF-alpha (show TNF Antibodies) can stimulate MMP-2/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases

  2. Results provide evidence that MMP-2 bears the potentiality to cleave alpha-DG enriched from rabbit skeletal muscle indicating that this degradation indeed might also occur in vivo.

  3. In conclusion, MMP-2 could be responsible for the proteolysis of dystrophin (show DMD Antibodies).

  4. Castor (show CASZ1 Antibodies) oil polymer induces bone formation with high matrix metalloproteinase-2 expression.

  5. MMP2 spinal cord expression is increased in cervical spondylotic myelopathy.

  6. Ulinastatin (show AMBP Antibodies) effectively inhibited the increased expression of MMP-2, MMP-3 (show MMP3 Antibodies), and iNOS (show NOS2 Antibodies) in degenerated NP cells induced by IL-1beta (show IL1B Antibodies) in vitro.

  7. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2, MMP-9 (show MMP9 Antibodies) and TIMP-1 (show TIMP1 Antibodies) in rabbits with acute paraquat poisoning.

  8. The RNA interference targeting COX-2 (show COX2 Antibodies) can effectively inhibit the expression of COX-2 (show COX2 Antibodies) and MMP-2 in IL-1alpha stimulated rabbit corneal stromal cells in vitro.

  9. Our results strongly suggest that ischaemic postconditioning may exert part of its cardioprotective effects through the inhibition of MMP-2 activity.

MMP2 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MMP2

  • matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (MMP2) antibody
  • Matrix metalloproteinase 2 (Mmp2) antibody
  • matrix metalloproteinase 2 (mmp2) antibody
  • matrix metalloproteinase-2 (mmp-2) antibody
  • matrix metalloproteinase 2 (Mmp-2) antibody
  • matrix metalloproteinase-2 (LOC100135793) antibody
  • matrix metallopeptidase 2 (Mmp2) antibody
  • 2-MMP antibody
  • anon-WO0118547.84 antibody
  • CG1794 antibody
  • CLG4 antibody
  • CLG4A antibody
  • dm-2MMP antibody
  • Dm2-MMP antibody
  • Dmel\\CG1794 antibody
  • dmmp2 antibody
  • fgmmp-2 antibody
  • GelA antibody
  • l(2)02353 antibody
  • LOC100135793 antibody
  • MMP-2 antibody
  • MMP-II antibody
  • mmp2 antibody
  • MONA antibody
  • TBE-1 antibody
  • wu:fa99h12 antibody
  • wu:fk89d01 antibody

Protein level used designations for MMP2

CG1794-PB , CG1794-PC , CG1794-PD , Mmp2-PB , Mmp2-PC , Mmp2-PD , matrix metalloprotease 2 , matrix metalloproteinase , matrix metalloproteinase 2 , 72 kDa type IV collagenase , Gelatinase A , matrix metalloproteinase-2 , 72 kDa gelatinase , MMP-2 , gelatinase A , 72kD gelatinase , 72kD type IV collagenase , 72kDa gelatinase , 72kDa type IV collagenase , collagenase type IV-A , matrix metalloproteinase-II , neutrophil gelatinase , matrix metalloproteinase 2 (72 KDa type IV collagenase) , matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

100033948 Equus caballus
35997 Drosophila melanogaster
337179 Danio rerio
653022 Takifugu rubripes
657982 Tribolium castaneum
100135793 Oncorhynchus mykiss
81686 Rattus norvegicus
17390 Mus musculus
4313 Homo sapiens
282872 Bos taurus
386583 Gallus gallus
403733 Canis lupus familiaris
397391 Sus scrofa
100009000 Oryctolagus cuniculus
443115 Ovis aries
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