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anti-Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) Antibodies

The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. Additionally we are shipping MAP3K10 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAP3K10 308463  
MAP3K10 4294 Q02779
MAP3K10 269881  
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Top anti-MAP3K10 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-MLK2 Pab (ABIN392424) is used in Western blot to detect MLK2 in transfected COS7 cell lysate. Data is kindly provided by Drs. M.K. Barthwal and A. Rana from Texas A&M University, Health Science Center (Temple, TX). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MAP3K10 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MAP3K10 AntibodyTitration: 1.0 µg/mL  Positive Control: THP-1 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of MLK2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of MLK2 expression in HeLa (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Mouse Map3k10 Antibody (N-term) (ABIN658183) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the Map3k10 antibody detected the Map3k10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details

MAP3K10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)
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Human , ,
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Mouse (Murine) , ,
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Top referenced anti-MAP3K10 Antibodies

  1. Human Polyclonal MAP3K10 Primary Antibody for IHC (p), WB - ABIN392424 : Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN392424

  2. Human Polyclonal MAP3K10 Primary Antibody for EIA, IHC (p) - ABIN360309 : Katoh, Hirai, Sugimura, Terada: Cloning and characterization of MST, a novel (putative) serine/threonine kinase with SH3 domain. in Oncogene 1995 (PubMed)
    Show all 2 references for ABIN360309

More Antibodies against MAP3K10 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. MAP3K4 (show MAP3K4 Antibodies) is sufficiently mediate the TGFbeta (show TGFB1 Antibodies)-induced phosphorylation of p38 MAPK (show MAPK14 Antibodies) in MEFs and HaCaT cells.

  2. A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.

  3. This study showed that show that RUNX3 (show RUNX3 Antibodies) is a principal and evolutionarily conserved component of the MST pathway.

  4. Mechanism of MAP kinase (show MAPK1 Antibodies) activation by TNF (show TNF Antibodies) requires Src (show SRC Antibodies)-dependent activation of Vav (show VAV1 Antibodies), activation of Rac (show AKT1 Antibodies)/Cdc42 (show CDC42 Antibodies), and the engagement of the Rac (show AKT1 Antibodies)/Cdc42 (show CDC42 Antibodies) interaction site on MLK2 and 3.

  5. Data show that miR (show MLXIP Antibodies)-181b contributed to proliferation of AML (show RUNX1 Antibodies) cells by targeting MLK2.

  6. MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin

  7. demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 (show NR0B1 Antibodies) and thyroid hormone receptor (show THRA Antibodies) mediated transcriptional silencing is strongly enhanced in the presence of active MLK2

  8. MLK2 and -3 are required for activation of JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) by ectopically expressed GCK (show GCK Antibodies)

  9. Hippocalcin (show HPCA Antibodies) and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons.

  10. Mixed lineage kinase (show MAP3K12 Antibodies) phosphorylates transcription factor E47 (show TCF3 Antibodies) and inhibits TrkB (show NTRK2 Antibodies) expression to link neuronal death and survival pathways

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. There is extensive functional redundancy between MLK1 (show MAP3K9 Antibodies) and MLK2, and the other member of the family, MLK3 (show KCNK7 Antibodies), none of which are required for survival in mouse.

  2. Mixed lineage kinase (show MAP3K12 Antibodies) phosphorylates transcription factor E47 (show TCF3 Antibodies) and inhibits TrkB (show NTRK2 Antibodies) expression to link neuronal death and survival pathways

MAP3K10 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Gene names and symbols associated with MAP3K10

  • mitogen-activated protein kinase kinase kinase 10 (MAP3K10) antibody
  • mitogen activated protein kinase kinase kinase 10 (Map3k10) antibody
  • mitogen-activated protein kinase kinase kinase 10 (Map3k10) antibody
  • mitogen-activated protein kinase kinase kinase 10 (map3k10) antibody
  • BC028668 antibody
  • BC046514 antibody
  • MEKK10 antibody
  • mlk2 antibody
  • MST antibody
  • xmlk2 antibody

Protein level used designations for MAP3K10

mitogen-activated protein kinase kinase kinase 10 , mixed-lineage kinase 2 , MKN28 derived nonreceptor_type serine/threonine kinase , MKN28 kinase , mixed lineage kinase 2 , protein kinase MST , MKN28 derived nonreceptor_type , serine/threonine kinase

GENE ID SPECIES
700477 Macaca mulatta
100017495 Monodelphis domestica
100067981 Equus caballus
100343621 Oryctolagus cuniculus
308463 Rattus norvegicus
4294 Homo sapiens
269881 Mus musculus
484504 Canis lupus familiaris
100521453 Sus scrofa
781037 Bos taurus
398612 Xenopus laevis
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