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NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Additionally we are shipping and many more products for this protein.
Showing 10 out of 53 products:
Human Polyclonal NLRP4 Primary Antibody for EIA, WB - ABIN783705
Tian, Pascal, Monget: Evolution and functional divergence of NLRP genes in mammalian reproductive systems. in BMC evolutionary biology 2009
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Human Polyclonal NLRP4 Primary Antibody for IHC, IHC (p) - ABIN4337762
Jounai, Kobiyama, Shiina, Ogata, Ishii, Takeshita: NLRP4 negatively regulates autophagic processes through an association with beclin1. in Journal of immunology (Baltimore, Md. : 1950) 2011
Show all 2 references for ABIN4337762
This study describes conformational stability of native NLRP14 (show NLRP14 Antibodies) and mutants in their monomeric and dimeric states and compares them to NLRP4, a representative of a native pyrin (show MEFV Antibodies) domain fold.
Findings suggest that NLR family pyrin domain containing 2 (show NLRP2 Antibodies) (NLRP2P) is a processed pseudogene that regulates NF-kappaB (show NFKB1 Antibodies) RelA/p65 (show NFkBP65 Antibodies) activity and thus represents the newest member of the POP (show PREP Antibodies) family, pyrin (show MEFV Antibodies)-only protein 4 (POP4 (show POP4 Antibodies); NLRP4).
Structural and functional analysis of the NLRP4 pyrin (show MEFV Antibodies) domain.
Our results provide molecular insight into the mechanisms by which NLRP4-DTX4 (show DTX4 Antibodies) targets TBK1 (show TBK1 Antibodies) for degradation.
NLRP4 is recruited to and accumulates in bacteria-containing phagosomes and transiently dissociates from beclin1 (show BECN1 Antibodies) following group A streptococcus infection, thereby controlling the autophagic flux crucial for cell-autonomous antibacterial resistance.
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV\; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1\; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003
NACHT, leucine rich repeat and PYD containing 4
, NLR family, pyrin domain containing 4E
, NLR family, pyrin domain containing 4
, NACHT, LRR and PYD domains-containing protein 4-like
, NACHT, LRR and PYD containing protein 4
, NACHT, LRR and PYD domains-containing protein 4
, PAAD and NACHT-containing protein 2
, PYRIN and NACHT-containing protein 2
, PYRIN-containing APAF1-like protein 4
, cancer/testis antigen 58
, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4
, ribonuclease inhibitor 2
, NACHT, LRR and PYD domains-containing protein 4A
, NACHT, leucine rich repeat and PYD containing 4A
, NACHT/LRR/pyrin domain-containing protein 4