anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) Antibodies

The protein encoded by NLRP6 binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NLRP6 171389 P59044
NLRP6 101613 Q91WS2
NLRP6 171390 Q63035
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Top anti-NLRP6 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB NLRP6Antibody (N-term) (ABIN657452) western blot analysis in human placenta tissue lysates (35 µg/lane). This demonstrates the NLRP6 antibody detected the NLRP6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Formalin-fixed and paraffin embedded mouse intestine tissue labeled with Rabbit Anti-NALP6 Polyclonal Antibody, Unconjugated (ABIN2559652) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney tissue labeled with Rabbit Anti-NALP6 Polyclonal Antibody, Unconjugated (ABIN2559652) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 Monoclonal Antibody. Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & 100 μg Log in to see 8 to 9 Days
$273.00
Details
Human Mouse PE FACS Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 PE-conjugated Monoclonal Antibody. Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 PE-conjugated Monoclonal Antibody. To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & 25 Tests Log in to see 8 to 9 Days
$199.50
Details
Mouse Rabbit Un-conjugated WB Mouse Nlrp6 Antibody  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Nlrp6 antibody detected the Nlrp6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of bioptic sections of small intestine using anti-NLRP6/NALP6 (human), mAb (Clint-1)  at 1:500 dilution. Method: A) Epithelial tissues which express NLRP6 (positive control) (black arrows) and connective tissues which do not express NLRP6 (negative control) (red arrows) are stained using Clint-1. B) Control confirming non-reactive specificity of the secondary antibody without Clint-1. 100 μg Log in to see 5 to 8 Days
$425.25
Details
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Biotin IHC (p)   100 μL Log in to see 14 to 21 Days
$383.90
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: NALP6 Antibody [NBP2-31372] - WB detection of NALP6 protein (NACHT, LRR and PYD domains-containing protein 6) in (A) Jurkat cells lysate and (B) partial recombinant protein using NALP6 antibody at a concentration of 1 ug/ml for lysate and 0.1 ug/ml for the recombinant protein. In Jurkat cells lysate, this antibody detected a major band at ~98.8 kDa which the expected position for NALP6. Immunohistochemistry-Paraffin: NALP6 Antibody [NBP2-31372] - IHC-P analysis of NALP6 protein in a section of human breast normal tissue using NALP6 antibody at a concentration of 5 ug/ml. The breast ductal /acinar epithelium showed a strong NALP6 positivity in the cytoplasm and nuclei of the cells. 0.1 mg Log in to see 7 to 9 Days
$317.63
Details

NLRP6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against NLRP6 Interaction Partners

Human NLR Family, Pyrin Domain Containing 6 (NLRP6) interaction partners

  1. this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease

  2. Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2 (show TAB2 Antibodies)/3 and TRIM38 (show TRIM38 Antibodies) in RA synoviocytes in response to TNFalpha (show TNF Antibodies). (NLRP6 = ; TAB2 (show TAB2 Antibodies)/3 = transforming growth factor-b (show ATP5S Antibodies)-activated kinase 1-binding protein 2/3; TRIM38 (show TRIM38 Antibodies) = tripartite motif 38)

  3. Our results revealed an association between NLRP6/AVR and ADM (show ADM Antibodies) loci with male essential hypertension, suggesting the existence of sex-specific NLRP6/AVR and ADM (show ADM Antibodies) variants affecting male susceptibility to essential hypertension.

  4. We will focus on NLRP6 and NLRP12 (show NLRP12 Antibodies).

  5. NLRP6 is a newly characterized member of this family that inhibits NF-kappaB (show NFKB1 Antibodies) and MAP-kinase (show MAPK1 Antibodies) dependent immune signaling to hamper anti-microbial defense.

  6. AVR is distinct from Nalp6/PYPAF5 based on different mRNA and protein sizes, subcellular localization, and tissue-specific expression patterns.

  7. The dual AngII/AVP (show AVP Antibodies) receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model.

  8. This publication deals with the rat ortholog of the human NLRP6 gene.

  9. This publication deals with the rat ortholog of the human NLRP6 gene.

  10. A. actinomycetemcomitans enhances NLRP3 (show NLRP3 Antibodies) and reduces NLRP6 inflammasome expression.

Mouse (Murine) NLR Family, Pyrin Domain Containing 6 (NLRP6) interaction partners

  1. this study shows that Nlrp6-dependent Inflammasomes do not shape the commensal gut (show GUSB Antibodies) microbiota composition

  2. this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease

  3. Study identified a set of microbiota-modulated metabolites whose integrative activity drives NLRP6 inflammasome activation and downstream epithelial IL-18 (show IL18 Antibodies)-induced anti-microbial peptide secretion, thereby providing favorable conditions for WT microbiota colonization.

  4. Nlrp6 contributes to recovery from peripheral nerve injury by dampening inflammatory responses independently of IL-1beta (show IL1B Antibodies) and inflammasomes

  5. These data demonstrate that Nlrp6 functions with Dhx15 (show DHX15 Antibodies) as a viral RNA sensor to induce IFN-stimulated genes , and this effect is especially important in the intestinal tract.

  6. Study demonstrates that NLRP6 is important in maintaining autophagy in the intestinal epithelium, a process previously shown to be critically important in intestinal granule exocytosis pathway.

  7. Exposure of mice to stress inhibits NLRP6 and alters the composition of the gut (show GUSB Antibodies) microbiota, leading to intestinal inflammation.

  8. AVR is distinct from Nalp6/PYPAF5 based on different mRNA and protein sizes, subcellular localization, and tissue-specific expression patterns.

  9. The dual AngII/AVP (show AVP Antibodies) receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model.

  10. This publication deals with the rat ortholog of the mouse Nlrp6 gene.

NLRP6 Antigen Profile

Protein Summary

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation.

Gene names and symbols associated with NLRP6

  • NLR family, pyrin domain containing 6 (NLRP6) antibody
  • NLR family, pyrin domain containing 6 (Nlrp6) antibody
  • AI504961 antibody
  • Avr antibody
  • CLR11.4 antibody
  • Nalp6 antibody
  • Navr antibody
  • Navr/Avr antibody
  • NLRP6 antibody
  • PAN3 antibody
  • Pypaf5 antibody

Protein level used designations for NLRP6

NLR family, pyrin domain containing 6 , NACHT, leucine rich repeat and PYD containing 6 , NLR family pyrin domain-containing protein 6 , NACHT, LRR and PYD domains-containing protein 6-like , NACHT, LRR and PYD containing protein 6 , NACHT, LRR and PYD domains-containing protein 6 , PYRIN-containing APAF1-like protein 5 , angiotensin II/vasopressin receptor , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6 , NACHT/LRR/pyrin domain-containing protein 6 , non-angiotensin-vasopressin receptor , angiotensin/vasopressin receptor , dual angiotensin II/vasopressin receptor

GENE ID SPECIES
466301 Pan troglodytes
483394 Canis lupus familiaris
505101 Bos taurus
720741 Macaca mulatta
100414562 Callithrix jacchus
100469211 Ailuropoda melanoleuca
100519245 Sus scrofa
171389 Homo sapiens
101613 Mus musculus
171390 Rattus norvegicus
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