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Stress-activated kinase involved in tolerance to glucose starvation. Additionally we are shipping NUAK Family, SNF1-Like Kinase, 2 Proteins (6) and many more products for this protein.
Showing 10 out of 70 products:
Human Polyclonal NUAK2 Primary Antibody for EIA, WB - ABIN953771
Koh, Toyoda, Fujii, Jung, Rathod, Middelbeek, Lessard, Treebak, Tsuchihara, Esumi, Richter, Wojtaszewski, Hirshman, Goodyear: Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 5 references for ABIN953771
Human Polyclonal NUAK2 Primary Antibody for ICC, IF - ABIN4340883
Kim, Lee, Chae, Kang, Lee, Oh, Kim, Kim, Kim: Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer. in Oncology 2013
Show all 2 references for ABIN4340883
Human Polyclonal NUAK2 Primary Antibody for EIA, WB - ABIN359317
Rennie, Fraser: The Islets of Langerhans in Relation to Diabetes. in The Biochemical journal 2006
Human Polyclonal NUAK2 Primary Antibody for WB - ABIN391234
Lefebvre, Bai, Shahmolky, Sharma, Poon, Drucker, Rosen: Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK. in The Biochemical journal 2001
Sucrose non-fermenting AMPK (show PRKAA1 Antibodies) related kinase/Pentraxin 3 (show PTX3 Antibodies) combined role in immunometabolic signaling and DNA damage response is proposed to accelerate cardiovascular complications in systemic lupus erythematosus patients
NUAK2 silencing and inactivation of the PI3K (show PIK3CA Antibodies) pathway efficiently controlled CDK2 (show CDK2 Antibodies) expression, whereas CDK2 (show CDK2 Antibodies) inactivation specifically abrogated the growth of NUAK2-amplified and PTEN (show PTEN Antibodies)-deficient melanoma cells.
The AMPK (show PRKAA1 Antibodies)-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-beta (show TGFB1 Antibodies) signaling.
Activation of AMP-activated protein kinase (show PRKAA2 Antibodies) protects the integrity of the blood-brain barrier by suppressing the induction of NADPH oxidase (show NOX1 Antibodies)-derived superoxide anions.
Considers possible roles of NUAK2 in tumorigenesis in general and suggest that NUAK2 has pivotal roles in acral melanomagenesis.
MLCP (myosin light chain phosphatase) activation is counteracted by a previously unrecognized association between MRIP (myosin phosphatase Rho-interacting protein (show MPRIP Antibodies)) and the inducible kinase NUAK2
This study further supports the importance of NUAK2 in cancer development and tumor progression, while AMPK (show PRKAA1 Antibodies) has antioncogenic properties.
Data show that SNARK is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle.
SNARK is an NF-kappaB (show NFKB1 Antibodies)-regulated anti-apoptotic gene that contributes to the tumor-promoting activity of CD95 (show FAS Antibodies) in apoptosis-resistant tumor cells
These data suggests different phosphorylation and regulation of MYPT1 (show PPP1R12A Antibodies) activity by NUAK2.
These findings reveal a critical role for SNARK in myocyte survival and the maintenance of muscle mass with age.
NUAK1 (show NUAK1 Antibodies) and NUAK2 complementarily function in the apical constriction and apico-basal elongation that associate with the dorsolateral hinge point formation in cephalic neural plate during the 5- to 10-somite stages.
Obesity was a risk factor for colorectal tumorigenesis in Snark(+/-) mice model.
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1 (By similarity).
NUAK family SNF1-like kinase 2
, SNF1/AMP activated protein kinase
, SNF1/AMP kinase-related kinase
, omphalocele kinase 2
, SNF1/AMP-activated protein kinase