anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) Antibodies

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Additionally we are shipping NUDT15 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NUDT15 55270 Q9NV35
NUDT15 214254 Q8BG93
NUDT15    
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Top anti-NUDT15 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Immunohistochemistry analysis in human breast tissuee (Formalin-fixed, Paraffin-embedded) using NUDT15  Antibody  (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NUDT15 antibody  for IHC. Clinical relevance has not been evaluated. Western blot analysis in HepG2 cell line lysates (35ug/lane) using NUDT15  Antibody (C-term). This demonstrates the NUDT15 antibody detected the NUDT15 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Nudt15 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB NUDT15 antibody (C-term) (ABIN654983) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissuee followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using NUDT15 antibody. Immunohistochemistry of paraffin-embedded human liver using NUDT15 antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of NUDT15 staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with th Western blot analysis of NUDT15 expression in HT29 (A), SW480 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: NUDT15 Antibody [NBP2-38436] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB   400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, FACS, IHC, WB   200 μL Log in to see 7 to 9 Days
$713.17
Details
Human Rabbit PE FACS, IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details

NUDT15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Mouse (Murine)


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Cow (Bovine)


Top referenced anti-NUDT15 Antibodies

  1. Human Polyclonal NUDT15 Primary Antibody for EIA, FACS - ABIN953779 : Hori, Satou, Harashima, Kamiya: Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5. in Free radical biology & medicine 2010 (PubMed)
    Show all 2 references for 953779

More Antibodies against NUDT15 Interaction Partners

Human Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) interaction partners

  1. NUDT15 gene polymorphism is related to mercaptopurine intolerance in Taiwan Chinese children with acute lymphoblastic leukemia.

  2. our results defined how NUDT15 limits thiopurine efficacy and how genetic ablation via the R139C missense mutation confers sensitivity to thiopurine treatment in patients

  3. NUDT15 polymorphisms are associated with 6-mercaptopurine intolerance in children treated for acute lymphoblastic leukemia.

  4. NUDT15 c.415C>T may be another predictor of AZA-induced leukocytopenia.

  5. our study shows that 6-MP reduction is significant in the younger age group in relation to NUDT15 variant

  6. Letter: discuss role of NUDT15 in complex thiopurine metabolism.

  7. There was a close association of NUDT15 R139C with early leukopenia associated with thiopurines in patients in Hong Kong

  8. These results suggest that NUDT15 R139C-related thiopurine-induced leukocytopenia is mediated by a 6-TGN (show TG Antibodies)-independent mechanism.

  9. Mutations of the NUDT15 and TPMT (show TPMT Antibodies) gene accounted for approximately 88% of cases with thiopurine-induced early leukopenia. Extensive hair loss was a recognizable early symptom in patients with the homozygous NUDT15 c.415C>T variant.

  10. NUDT15 c.415C>T increases risk of 6-mercaptopurine induced myelosuppression during maintenance therapy in children with acute lymphoblastic leukemia.

Mouse (Murine) Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) interaction partners

  1. These results suggest that the MTH2 deficiency might be one of the causative factors for accelerated aging.

  2. MTH2 has a potential to protect the genetic material from the untoward effects of endogenous oxygen radicals; MTH2 could act as an MTH1 (show NUDT1 Antibodies) redundancy factor [MTH2]

NUDT15 Antigen Profile

Protein Summary

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.

Gene names and symbols associated with NUDT15

  • nudix (nucleoside diphosphate linked moiety X)-type motif 15 (NUDT15) antibody
  • nudix (nucleoside diphosphate linked moiety X)-type motif 15 (Nudt15) antibody
  • 6530403O17 antibody
  • A730068G11Rik antibody
  • MTH2 antibody
  • RP11-90M2.1 antibody

Protein level used designations for NUDT15

7,8-dihydro-8-oxoguanine-triphosphatase NUDT15 , 8-oxo-dGTPase NUDT15 , A730068G11Rik , mutT homolog 2 , nucleoside diphosphate-linked moiety X motif 15 , nudix motif 15 , nudix-type motif 15 , probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 , probable 8-oxo-dGTP diphosphatase NUDT15 , MutT homolog 2 , mMTH2

GENE ID SPECIES
55270 Homo sapiens
214254 Mus musculus
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