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PITPNM Family Member 3 Proteins (PITPNM3)

PITPNM3 encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. Additionally we are shipping PITPNM Family Member 3 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PITPNM3 83394 Q9BZ71
PITPNM3 327958 Q3UHE1
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Top PITPNM Family Member 3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PITPNM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for PITPNM Family Member 3 (PITPNM3) Interaction Partners

Human PITPNM Family Member 3 (PITPNM3) interaction partners

  1. Data indicate that PYK2 N-terminal domain interacting receptor 1 (Nir1) could induce epithelial-mesenchymal transition by stabilising Snail (show SNAI1 Proteins) via the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/GSK3beta/Snail (show SNAI1 Proteins) signalling pathway through binding to CCL18 (show CCL18 Proteins).

  2. Our observations of the PITPNM3 p.Q626H mutation carriers confirm that CORD5 (show GUCY2D Proteins) is a disease not to mix with other retinal degenerations mapped to 17p13.

  3. CCL18 (show CCL18 Proteins) derived from Tumor-associated macrophages (TAMs) lays a critical role in promoting breast cancer metastasis via its receptor, PITPNM3.

  4. Thus, mutations in PITPNM3 do not appear to be a major cause of cone or cone-rod dystrophy.

  5. Our finding on the first mutation in the human homologue of Drosophila rdgB (show PITPNM1 Proteins) indicates novel pathways and a potential important role of the PITPNM3 in mammalian phototransduction.

  6. Mutation in the PYK2 (show PTK2B Proteins)-binding domain of PITPNM3 causes autosomal dominant cone dystrophy (CORD5 (show GUCY2D Proteins)) in two Swedish families.

PITPNM Family Member 3 (PITPNM3) Protein Profile

Protein Summary

This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PITPNM3

  • PITPNM family member 3 (PITPNM3)
  • PITPNM family member 3 (Pitpnm3)
  • A330068P14Rik protein
  • Ackr6 protein
  • AI848332 protein
  • CORD5 protein
  • Gm880 protein
  • NIR1 protein
  • RDGBA3 protein

Protein level used designations for PITPNM3

NIR-1 , PITPnm 3 , PYK2 N-terminal domain-interacting receptor 1 , atypical chemokine receptor 6 , cone rod dystrophy 5 , membrane-associated phosphatidylinositol transfer protein 3 , phosphatidylinositol transfer protein, membrane-associated 3 , retinal degeneration B alpha 3 , pyk2 N-terminal domain-interacting receptor 1

GENE ID SPECIES
83394 Homo sapiens
327958 Mus musculus
489445 Canis lupus familiaris
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