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anti-Polymeric Immunoglobulin Receptor (PIGR) Antibodies

PIGR is a member of the immunoglobulin superfamily. Additionally we are shipping PIGR Proteins (42) and PIGR Kits (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIGR 25046 P15083
PIGR 5284 P01833
PIGR 18703 O70570
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Top anti-PIGR Antibodies at antibodies-online.com

Showing 10 out of 132 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of PIGR Antibody (C-term) (ABIN652495) in HepG2,K562,HL-60 cell line lysates (35 µg/lane).PIGR (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with PIGR Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PIGR Antibody (C-term) in HepG2,K562,HL-60 cell line lysates (35ug/lane).PIGR (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-PIGR antibody  ABIN1049233 IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-PIGR antibody  ABIN960799 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-PIGR antibody  ABIN960799 IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using PIGR, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p) Anti-PIGR antibody  ABIN960798 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-PIGR antibody  ABIN960798 IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$273.90
Details

PIGR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PIGR Antibodies

  1. Mouse (Murine) Polyclonal PIGR Primary Antibody for ELISA - ABIN2000383 : Kaetzel: Polymeric Ig receptor: defender of the fort or Trojan horse? in Current biology : CB 2001 (PubMed)
    Show all 2 references for ABIN2000383

  2. Human Polyclonal PIGR Primary Antibody for FACS, IF - ABIN652495 : Orzech, Cohen, Weiss, Aroeti: Interactions between the exocytic and endocytic pathways in polarized Madin-Darby canine kidney cells. in The Journal of biological chemistry 2000 (PubMed)

More Antibodies against PIGR Interaction Partners

Rhesus Monkey Polymeric Immunoglobulin Receptor (PIGR) interaction partners

  1. Both pIgR and FcRn mRNA levels were significantly reduced in the duodenal mucosa during acute SHIV infection and in the jejunum and caecum during chronic SHIV/SIV infection.

Human Polymeric Immunoglobulin Receptor (PIGR) interaction partners

  1. Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis.

  2. Crohn disease patients were characterized as having decreased median expression of PIGR, in non-inflamed colonic mucosa. By contrast, Ulcerative colitis patients exhibited decreased expression of PIGR in colon mucosa.

  3. These results demonstrate that SLPI (show SLPI Antibodies) down-regulates pIgR expression through the NF-kappaB (show NFKB1 Antibodies) signaling pathway by inhibiting degradation of IkappaBbeta (show NFKBIB Antibodies) protein.

  4. Report PIGR expression in human fallopian tubes, primary epithelial ovarian tumours and metastases.

  5. the polymeric immunoglobulin receptor (pIgR) is highly expressed by renal cyst-lining cells. pIgR expression is, in part, driven by aberrant STAT6 (show STAT6 Antibodies) pathway activation.

  6. Positive expression of pIgR was statistically significantly associated with poor prognosis of patients with colon carcinoma hepatic metastasis.

  7. In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway.

  8. Polymeric immunoglobulin receptor expression is correlated with poor prognosis in patients with osteosarcoma.

  9. High PIGR expression independently predicts a decreased risk of recurrence and an improved survival in patients with adenocarcinoma of the upper gastrointestinal tract

  10. pIgR down-regulation in chronic obstructive pulmonary disease correlates with severity. Bronchial epithelium in vitro retains aberrant imprinting for pIgR expression. pIgR down-regulation is linked to TGF-beta (show TGFB1 Antibodies)-driven reprogramming of bronchial epithelium.

Cow (Bovine) Polymeric Immunoglobulin Receptor (PIGR) interaction partners

  1. This study evaluated the production of polymeric immunoglobulin receptor and immunoglobulin A in the salivary glands of cattle.

Mouse (Murine) Polymeric Immunoglobulin Receptor (PIGR) interaction partners

  1. pIgR/SIgA deficiency in the airways leads to persistent activation of innate immune responses to resident lung microbiota, driving progressive small airway remodelling and emphysema.

  2. Increased autoimmune diabetes in Pigr-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4.

  3. the polymeric immunoglobulin receptor (pIgR) is highly expressed by renal cyst-lining cells. pIgR expression is, in part, driven by aberrant STAT6 (show STAT6 Antibodies) pathway activation.

  4. In a mouse intestinal explant model, the heat-inactivated potential probiotic BB6378 increases intestinal pIgR expression in a site-specific manner on the epithelium via MyD88 (show MYD88 Antibodies).

  5. pIgR on the blood-brain barrier endothelium may represent a novel pneumococcal adhesion receptor.

  6. Results reveal a novel Yes-EGFR (show EGFR Antibodies)-ERK (show EPHB2 Antibodies)-FIP5 signalling network for regulation of pIgA (show PIGA Antibodies)-pIgR transcytosis.

  7. Blockade of transepithelial transport of dimeric IgA in pIgR knockout mice reduces the degree of protection or cross-protection against viral infection, in parallel with a marked increase in serum IgA concentration and decrease in nasal IgA concentration.

  8. Mice deficient in SIgA have been generated by knocking out the pIgR and assessing their ability to maintain normal mucosal homeostasis and to induce mucosal and systemic immune responses against pathogenic and nonpathogenic stimuli.

  9. Mice that lack expression of the polymeric immunoglobulin receptor have approximately 5-fold more systemic IgA and 6-fold less nasal IgA antibodies than wild-type mice due to defective IgA transport into mucosal tissues.

  10. Data suggest that the pIgR and/or the secretory component are important for the maintenance of epithelial integrity and mucosal homeostasis in the colonic epithelium.

PIGR Antigen Profile

Protein Summary

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells\; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

Gene names and symbols associated with PIGR

  • polymeric immunoglobulin receptor (PIGR) antibody
  • polymeric immunoglobulin receptor (Pigr) antibody
  • DKFZp469G1013 antibody
  • pIgA-R antibody
  • RNPIGR2 antibody

Protein level used designations for PIGR

polymeric immunoglobulin receptor , polymeric immunoglobulin receptor-like , poly-Ig receptor , polymeric IgA receptor , hepatocellular carcinoma associated protein TB6 , hepatocellular carcinoma-associated protein TB6 , phosphatidylinositol glycan, class R , poly-IG receptor

GENE ID SPECIES
419848 Gallus gallus
457685 Pan troglodytes
694638 Macaca mulatta
100144764 Ovis aries
100171980 Pongo abelii
100387936 Callithrix jacchus
100583528 Nomascus leucogenys
25046 Rattus norvegicus
5284 Homo sapiens
474357 Canis lupus familiaris
281401 Bos taurus
18703 Mus musculus
397315 Sus scrofa
100328593 Oryctolagus cuniculus
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