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Premelanosome Protein Proteins

(Premelanosome Protein (PMEL))
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].
Melanoma gp100 Protein (AA 1-661) (GST tag) Melanoma gp100 Protein (AA 1-661) (GST tag) Melanoma gp100 Protein (AA 1-661) (GST tag) (ABIN1320014)

PMEL Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA

Melanoma gp100 Protein (AA 25-595) (Fc Tag) Melanoma gp100 Protein (AA 25-595) (Fc Tag) Melanoma gp100 Protein (AA 25-595) (Fc Tag) (ABIN6964099)

PMEL Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Melanoma gp100 Protein (AA 470-661) (His tag) (ABIN7393823)

PMEL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

Premelanosome Protein Proteins by Origin

Find Premelanosome Protein Proteins for a variety of species such as anti-Human Premelanosome Protein. The species listed below are among those available. Click on a link to go to the corresponding products.

Premelanosome Protein Proteins by Source

Here you will find Premelanosome Protein Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Premelanosome Protein Proteins by Protein Type

Here you can find Premelanosome Protein Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Premelanosome Protein Proteins by Application

Find Premelanosome Protein Proteins validated for a specific application such as SDS, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Premelanosome Protein Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320014
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964099
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393823
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710360
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713832
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725809
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1065487
Quantity 5 μg
Datasheet Datasheet

Latest Publications for our Premelanosome Protein Proteins

Rochin, Hurbain, Serneels, Fort, Watt, Leblanc, Marks, De Strooper, Raposo, van Niel: "BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 26, pp. 10658-63, (2013) (PubMed).

Aliases for Premelanosome Protein Proteins

premelanosome protein (PMEL) Proteins
premelanosome protein (Pmel) Proteins
premelanosome protein b (pmelb) Proteins
premelanosome protein a (pmela) Proteins
cb397 Proteins
D10H12S53E Proteins
D12S53E Proteins
D12S53Eh Proteins
fdv Proteins
gp87 Proteins
gp100 Proteins
ME20 Proteins
ME20-M Proteins
ME20M Proteins
MMP115 Proteins
P1 Proteins
P100 Proteins
PMEL17 Proteins
Pmel17 Proteins
pmel17 Proteins
RPE1 Proteins
sb:cb397 Proteins
SI Proteins
Si Proteins
SIL Proteins
SILV Proteins
Silv Proteins
silva Proteins
silver Proteins
silverb Proteins
wu:fc11g11 Proteins
wu:fj24g11 Proteins
zgc:136622 Proteins
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