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anti-Prohibitin 2 (PHB2) Antibodies

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Additionally we are shipping Prohibitin 2 Proteins (8) and Prohibitin 2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHB2 11331 Q99623
PHB2 12034 O35129
PHB2 114766 Q5XIH7
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Top anti-Prohibitin 2 Antibodies at antibodies-online.com

Showing 10 out of 120 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PHB2 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PHB2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate WB Suggested Anti-PHB2 Antibody Titration: 1 ug/mlPositive Control: Rat tissue 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PHB2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of PHB2 (arrow) using rabbit polyclonal PHB2 Antibody . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PHB2 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PHB2 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of PHB2 (arrow) using rabbit polyclonal PHB2 Antibody (Human C-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PHB2 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PHB2 (arrow) using PHB2 Antibody . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PHB2 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PHB2 (arrow) using rabbit polyclonal PHB2 Antibody (Human C-term) (ABIN391410). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PHB2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PHB2 Antibody (N-term) (ABIN391410), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PHB2-Y128 (ABIN391412) in 293 cell line lysates (35 µg/lane). PHB2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PHB2-Y128(ABIN391412) in mouse NIH-3T3 cell line lysates (35 µg/lane).PHB2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PHB2-Y248(ABIN391413) in MDA-MB435 cell line lysates (35 µg/lane).PHB2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PHB2-Y248 (ABIN391413) in mouse kidney tissue lysates (35 µg/lane). PHB2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-REA antibody, Western blotting Lane 1: PANC Cell Lysate Lane 2: COLO320 Cell Lysate Lane 3: U87Cell Lysate Lane 4: HEPA Cell Lysate Anti-REA antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

PHB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Prohibitin 2 Antibodies

  1. Human Polyclonal Prohibitin 2 Primary Antibody for EIA, IHC (p) - ABIN359501 : Takata, Matsunaga, Morimoto, Ma, Kurihara, Ono-Maniwa, Nakagawa, Azuma, Uchiyama, Fukui: PHB2 protects sister-chromatid cohesion in mitosis. in Current biology : CB 2007 (PubMed)
    Show all 2 references for ABIN359501

  2. Human Polyclonal Prohibitin 2 Primary Antibody for EIA, IHC (p) - ABIN359503 : Kasashima, Ohta, Kagawa, Endo: Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN359503

  3. Chicken Polyclonal Prohibitin 2 Primary Antibody for WB - ABIN2783329 : Ross, Nagy, Kirken: The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against Prohibitin 2 Interaction Partners

Human Prohibitin 2 (PHB2) interaction partners

  1. Fluorizoline bind to prohibitin (show PHB Antibodies), inducing mitochondrial apoptotic pathway through NOXA (show PMAIP1 Antibodies) and BIM (show BCL2L11 Antibodies) upregulation.

  2. REA modulates cross talk among multiple cell types in the uterine tissue and host background, serving as a brake on the estradiol-ER axis and restraining multiple aspects that contribute to the pathologic progression of endometriosis.

  3. BIG3 (show WDR5 Antibodies) may block the KPNAs (KPNA1 (show KPNA1 Antibodies), KPNA5 (show KPNA5 Antibodies), and KPNA6 (show KPNA6 Antibodies)) binding region(s) of PHB2.

  4. results show that PHB2 binds to the ligand binding domain of ERalpha (show ESR1 Antibodies) with a conformational change in the helix 12 of ERalpha (show ESR1 Antibodies)

  5. Functional analysis of selected regulated proteins revealed that knockdown of HNRPD (show HNRNPD Antibodies), PHB2 and UB2V2 (show UBE2V2 Antibodies) can increase HCMV replication, while knockdown of A4 and KSRP (show KHSRP Antibodies) resulted in decreased HCMV replication.

  6. These results demonstrate that estradiol upregulates REA expression and recruits REA via ERalpha (show ESR1 Antibodies) to the EREs on the RORgammaT promoter region, thus inhibiting RORgammaT expression and Th17 differentiation.

  7. BIG3 (ARFGEF3) is predicted to interact with its partner PHB2 through an ARM-type alpha-helical structure.

  8. Data indicate that the up-regulated expression of prohibitin (show PHB Antibodies) promoted acute promyelocytic leukemia (show PML Antibodies) cell line NB4-R1 cell apoptosis.

  9. PHB2 in hepatocellular carcinoma supports the development and progression of hepatocellular malignancy.

  10. Prohibitin 2 acts as a nuclear AKT (show AKT1 Antibodies) substrate during all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia (show PML Antibodies) cells

Mouse (Murine) Prohibitin 2 (PHB2) interaction partners

  1. Fluorizoline bind to prohibitin (show PHB Antibodies), inducing mitochondrial apoptotic pathway through NOXA (show PMAIP1 Antibodies) and BIM (show BCL2L11 Antibodies) upregulation.

  2. REA modulates cross talk among multiple cell types in the uterine tissue and host background, serving as a brake on the estradiol-ER axis and restraining multiple aspects that contribute to the pathologic progression of endometriosis.

  3. CARL can suppress mitochondrial fission and apoptosis by targeting miR (show MLXIP Antibodies)-539 and PHB2.

  4. These results demonstrate that estradiol upregulates REA expression and recruits REA via ERalpha (show ESR1 Antibodies) to the EREs on the RORgammaT promoter region, thus inhibiting RORgammaT expression and Th17 differentiation.

  5. results suggest that PHB2 is a crucial mitochondrial regulator for homeostasis and lineage-specific differentiation of ES cells.

  6. Loss of PHB2 impairs the stability of OPA1 (show MED12 Antibodies), affects mitochondrial ultrastructure, and induces the perinuclear clustering of mitochondria in hippocampal neurons

  7. REA physiologically restrains endometrial stromal cell decidualization, controlling the timing and magnitude of decidualization to coordinate uterine differentiation with concurrent embryo development that is essential for implantation and fertility.

  8. PHB1 (show PHB Antibodies) and PHB2 are critical mediators in promoting 3T3-L1 adipocyte differentiation and may be the potential targets for obesity therapies

  9. Optimal uterine development and functional activities require the normal gene dosage of REA, with partial or complete deletion resulting in hyperresponsiveness or underresponsiveness to hormone and subfertility or infertility, respectively.

  10. Serine phosphorylation of PHB2 by CaMK IV (show CAMK4 Antibodies) relieves its inhibition on MEF2 (show MEF2C Antibodies).

Prohibitin 2 (PHB2) Antigen Profile

Protein Summary

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity).

Gene names and symbols associated with anti-Prohibitin 2 (PHB2) Antibodies

  • prohibitin 2 (phb2) antibody
  • prohibitin 2 (PHB2) antibody
  • prohibitin 2 (TGas064h09.1) antibody
  • prohibitin 2 (Phb2) antibody
  • ATPHB2 antibody
  • AU044498 antibody
  • Bap antibody
  • Bap-37 antibody
  • bap37 antibody
  • Bcap27 antibody
  • Bcap37 antibody
  • DKFZp469N1310 antibody
  • F21M11.21 antibody
  • F21M11_21 antibody
  • p22 antibody
  • phb2 antibody
  • PNAS-141 antibody
  • prohibitin 2 antibody
  • prohibitin2 antibody
  • REA antibody
  • wu:fc28c08 antibody
  • xphb2 antibody
  • zgc:73150 antibody

Protein level used designations for anti-Prohibitin 2 (PHB2) Antibodies

B-cell receptor-associated protein 37 , prohibitin 2 , Prohibitin-2 , B-cell associated protein , B-cell receptor-associated protein BAP37 , D-prohibitin , prohibitin-2 , repressor of estrogen receptor activity , B-cell receptor associated protein 37

GENE ID SPECIES
324421 Danio rerio
451805 Pan troglodytes
549305 Xenopus (Silurana) tropicalis
839228 Arabidopsis thaliana
100172520 Pongo abelii
11331 Homo sapiens
446470 Xenopus laevis
771124 Gallus gallus
486716 Canis lupus familiaris
515363 Bos taurus
12034 Mus musculus
114766 Rattus norvegicus
Selected quality suppliers for anti-Prohibitin 2 (PHB2) Antibodies
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