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Proline Arginine Rich End Leucine Rich Repeat Protein Proteins (PRELP)

The protein encoded by PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. Additionally we are shipping PRELP Antibodies (52) and PRELP Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRELP 116847 Q9JK53
PRELP 5549 P51888
PRELP 84400 Q9EQP5
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Top PRELP Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,982.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PRELP Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,
Rat (Rattus)

More Proteins for Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) Interaction Partners

Mouse (Murine) Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) interaction partners

  1. Therefore, this study established a new role of PRELP in modulating beta-catenin (show CTNNB1 Proteins)/connexin43 (show GJA1 Proteins) pathway and osteoblast differentiation.

  2. when delivered via an AAV vector to the retina of mice, PRELP inhibited laser-induced choroidal neovascularization by 60%. PRELP reduced deposition of membrane attack complex in vivo by 25.5%.

  3. PRELP has a role in skeletal remodeling.

Human Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) interaction partners

  1. The unique expression of a 38 kDa PRELP in chronic lymphocytic leukemia (CLL) cells may suggest involvement in the pathobiology of CLL

  2. PRELP expression governs stem cells to differentiate into ligament tissue in a mouse model.

  3. PRELP may down-regulate complement attack at basement membranes and on damaged cartilage and therefore limit pathological complement activation in inflammatory disease such as RA.

  4. Relative abundance of PRELP mRNA and protein inhuman sclera, and observed age-related variation in scleral PRELP expression suggests that PRELP may play critical role in regulating biomechanical properties of scleral extracellular matrix.

  5. PRELP overexpression leads to a connective tissue phenotype in the skin, where the organization of collagen fibrils in the dermis was perturbed and the thickness of the hypodermal fat layer was diminished.

PRELP Protein Profile

Protein Summary

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene names and symbols associated with PRELP

  • proline arginine-rich end leucine-rich repeat (Prelp)
  • proline arginine-rich end leucine-rich repeat protein (LOC100354305)
  • proline/arginine-rich end leucine-rich repeat protein (PRELP)
  • proline/arginine-rich end leucine-rich repeat protein (Prelp)
  • 7330409J17Rik protein
  • MST161 protein
  • MSTP161 protein
  • SLRR2A protein

Protein level used designations for PRELP

prolargin , proline-arginine-rich end leucine-rich repeat protein , 55 kDa leucine-rich repeat protein of articular cartilage , prolargin proteoglycan , proline arginine-rich end leucine-rich repeat protein

GENE ID SPECIES
116847 Mus musculus
100354305 Oryctolagus cuniculus
5549 Homo sapiens
488561 Canis lupus familiaris
282000 Bos taurus
84400 Rattus norvegicus
419933 Gallus gallus
100726579 Cavia porcellus
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