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anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Antibodies

The product of RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. Additionally we are shipping RIPK3 Kits (14) and RIPK3 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RIPK3 11035 Q9Y572
RIPK3 56532  
RIPK3 246240 Q9Z2P5
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Top anti-RIPK3 Antibodies at antibodies-online.com

Showing 10 out of 153 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RIPK3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-RIPK3 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-RIPK3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate Immunohistochemistry with Spleen tissue at an antibody concentration of 5µg/ml using anti-RIPK3 antibody (AVARP00031_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB RIPK3 Antibody (C-term) (ABIN658475) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the RIPK3 antibody detected the RIPK3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human lung carcinoma tissue (Formalin-fixed, Paraffin-embedded) using RIPK3 / RIP3  Antibody (N-term), followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis of RIP3 / RIPK3 (arrow) in Ramos cell line lysates (35ug/lane) using RIPK3 / RIP3  Antibody (N-term). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human lung carcinoma tissue (Formalin-fixed, Paraffin-embedded) using RIPK3 / RIP3  Antibody , followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis of RIPK3 (arrow) in Hela cell line lysates (35ug/lane) using RIPK3 / RIP3  0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence of RIP3 in Rat Kidney cells with RIP3 antibody at 20 µg/ml. Immunohistochemistry of RIP3 in rat kidney tissue with RIP3 antibody at 5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of RIP3 (RIPK3) Antibody (N-term) (ABIN391272) in Ramos cell line lysates (35 µg/lane). RIPK3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RIP3 (RIPK3) antibody (N-term) (ABIN391272), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of hRIPK3-E504 (ABIN392275) in K562 cell line lysates (35 µg/lane). RIPK3 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of hRIPK3-E504 (ABIN392275) in mouse cerebellum tissue lysates (35 µg/lane). RIPK3 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details

RIPK3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RIPK3 Antibodies

  1. Human Polyclonal RIPK3 Primary Antibody for IHC (p), WB - ABIN392275 : Sun, Lee, Navas, Baldwin, Stewart, Dixit: RIP3, a novel apoptosis-inducing kinase. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN392275

  2. Mouse (Murine) Polyclonal RIPK3 Primary Antibody for EIA, IF - ABIN500612 : Pazdernik, Donner, Goebl, Harrington: Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kappaB. in Molecular and cellular biology 2000 (PubMed)
    Show all 3 references for ABIN500612

  3. Human Polyclonal RIPK3 Primary Antibody for EIA, IHC (p) - ABIN359363 : Yu, Huang, Shen, Quast, Chan, Xu, Nolan, Payan, Luo: Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. in Current biology : CB 1999 (PubMed)
    Show all 2 references for ABIN359363

  4. Cow (Bovine) Polyclonal RIPK3 Primary Antibody for IHC, WB - ABIN2777333 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2777333

  5. Human Polyclonal RIPK3 Primary Antibody for IHC (p), WB - ABIN658475 : He, Wang, Miao, Wang, Du, Zhao, Wang: Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. in Cell 2009 (PubMed)
    Show all 2 references for ABIN658475

  6. Human Polyclonal RIPK3 Primary Antibody for IHC (p), WB - ABIN391272 : Viringipurampeer, Ferreira, DeMaria, Yoon, Shan, Moosajee, Gregory-Evans, Ngai, Gregory-Evans: Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. in Human molecular genetics 2012 (PubMed)

  7. Cow (Bovine) Polyclonal RIPK3 Primary Antibody for IHC, WB - ABIN2792102 : Cerhan, Ansell, Fredericksen, Kay, Liebow, Call, Dogan, Cunningham, Wang, Liu-Mares, Macon, Jelinek, Witzig, Habermann, Slager: Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. in Blood 2007 (PubMed)

More Antibodies against RIPK3 Interaction Partners

Human Receptor-Interacting serine-threonine Kinase 3 (RIPK3) interaction partners

  1. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Antibodies)-RIPK3 necrosome formation leading to desensitization of TNF (show TNF Antibodies)-mediated necroptosis

  2. CNOT3 (show CNOT3 Antibodies) suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins, Ripk1 (show RIPK1 Antibodies) and Ripk3.

  3. RIPK3 expression may allow unmasking the necroptotic signalling machinery in melanoma and points to reactivation of this pathway as a treatment option for metastatic melanoma.

  4. Additionally, later in infection, RIP3 is cleaved by the coxsackievirus B3-encoded cysteine protease (show CTSB Antibodies) 3C(pro), which serves to abrogate RIP3-mediated necrotic signaling and induce a nonnecrotic form of cell death.

  5. Results identify a crucial role for RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell activation, and further suggest that RIPK3-PGAM5 signalling may mediate crosstalk between mitochondrial function and immune signalling.

  6. although JNK (show MAPK8 Antibodies) activation and RIP3 expression are induced by FS, neither contributes to the liver injury.

  7. The RIP3 expression is reduced in tumors compared to normal tissue in 85% of breast cancer patients, suggesting that RIP3 deficiency is positively selected during tumor growth/development.

  8. Data implicate the infiltrating macrophages as a source of damaging inflammasomes after photoreceptor detachment in a RIP3-dependent manner and suggest a novel therapeutic target for treatment of retinal diseases.

  9. PolyIC stimulation of cervical cancer cells induced necroptotic cell death, which was strictly dependent on the expression of the receptor-interacting protein (show RIPK1 Antibodies) kinase (show CDK7 Antibodies) RIPK3.

  10. Data suggest that neoalbaconol-induced necroptosis include receptor interacting serine/threonine kinase (show TLK2 Antibodies) 1-dependent expression of tumor necrosis factor alpha (show TNF Antibodies) and receptor interacting serine/threonine kinase 3-dependent generation of reactive oxygen species.

Mouse (Murine) Receptor-Interacting serine-threonine Kinase 3 (RIPK3) interaction partners

  1. we demonstrate that the phosphorylation of Ser345 is not required for the interaction between RIPK3 and MLKL in the necrosome, but is essential for MLKL translocation, accumulation in the plasma membrane, and consequent necroptosis.

  2. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Antibodies)-RIPK3 necrosome formation leading to desensitization of TNF (show TNF Antibodies)-mediated necroptosis

  3. Data indicate that receptor-interacting serine-threonine kinase 3 (RIPK3) deletion prevents inflammatory phenotypes in CreLysM (lysozyme (show LYZ Antibodies) M) Casp8fl/fl (caspase 8 (show CASP8 Antibodies)) mice.

  4. RIP3 (show MPRIP Antibodies)-induced activation of CaMKII (show CAMK2G Antibodies), via phosphorylation or oxidation or both, triggers opening of the mitochondrial permeability transition pore and myocardial necroptosis.

  5. RIPK3 is an essential molecule to maintain the temporal manner of the normal progression of wound closure

  6. deficiency of RIPK3 or MLKL prevents oxalate crystal-induced acute kidney injury.

  7. Results identify a crucial role for RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell activation, and further suggest that RIPK3-PGAM5 signalling may mediate crosstalk between mitochondrial function and immune signalling.

  8. although JNK (show MAPK8 Antibodies) activation and RIP3 (show MPRIP Antibodies) expression are induced by FS, neither contributes to the liver injury.

  9. RIPK3 can promote NLRP3 inflammasome and IL-1beta inflammatory responses independent of MLKL and necroptotic cell death

  10. Data implicate the infiltrating macrophages as a source of damaging inflammasomes after photoreceptor detachment in a RIP3 (show MPRIP Antibodies)-dependent manner and suggest a novel therapeutic target for treatment of retinal diseases.

RIPK3 Antigen Profile

Protein Summary

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Gene names and symbols associated with RIPK3

  • receptor-interacting serine-threonine kinase 3 (RIPK3) antibody
  • receptor-interacting serine-threonine kinase 3 (ripk3) antibody
  • receptor-interacting serine-threonine kinase 3 (Ripk3) antibody
  • 2610528K09Rik antibody
  • AW107945 antibody
  • Hcyp2 antibody
  • Rip3 antibody
  • RIPK3 antibody

Protein level used designations for RIPK3

receptor-interacting serine-threonine kinase 3 , receptor-interacting serine/threonine-protein kinase 3-like , RIP-3 , RIP-like protein kinase 3 , receptor interacting protein 3 , receptor-interacting protein 3 , receptor-interacting serine/threonine-protein kinase 3 , mRIP3 , homocysteine respondent protein HCYP2

GENE ID SPECIES
452820 Pan troglodytes
100461174 Pongo abelii
733239 Xenopus laevis
11035 Homo sapiens
56532 Mus musculus
246240 Rattus norvegicus
608486 Canis lupus familiaris
507427 Bos taurus
100734737 Cavia porcellus
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