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RNASEH2C encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Additionally we are shipping RNASEH2C Proteins (4) and many more products for this protein.
Showing 10 out of 19 products:
Human Polyclonal RNASEH2C Primary Antibody for EIA, FACS - ABIN954558
Chon, Vassilev, DePamphilis, Zhao, Zhang, Burgers, Crouch, Cerritelli: Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex. in Nucleic acids research 2009
Show all 3 references for ABIN954558
RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B (show RNASEH2B Antibodies)-dependent manner.
Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the C subunit of RNase H2.
Describes an RNASEH2C pseudogene that is located close to the SRY (show SRY Antibodies) gene on chromosome Y.
Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]
Data show that the interwoven architecture of RNase H2B (show RNASEH2B Antibodies) and RNase H2C that interface with RNase H2A (show RNASEH2A Antibodies) in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.
This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.
RNase H1 small subunit
, RNase H2 subunit C
, aicardi-Goutieres syndrome 3 protein
, ribonuclease H2 subunit C
, ribonuclease HI subunit C
, AYP1 protein