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The protein encoded by RLIM is a RING-H2 zinc finger protein. Additionally we are shipping RLIM Proteins (5) and many more products for this protein.
Showing 10 out of 61 products:
Human Polyclonal RLIM Primary Antibody for WB - ABIN1881751
Jonkers, Barakat, Achame, Monkhorst, Kenter, Rentmeester, Grosveld, Grootegoed, Gribnau: RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. in Cell 2009
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Human Monoclonal RLIM Primary Antibody for IF, WB - ABIN393526
Her, Chung: Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1. in The Journal of biological chemistry 2009
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Human Monoclonal RLIM Primary Antibody for IF, IP - ABIN565536
Zhou, Drabsch, Dekker, de Vinuesa, Li, Hawinkels, Sheppard, Goumans, Luwor, de Vries, Mesker, Tollenaar, Devilee, Lu, Zhu, Zhang, Dijke: Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling. in Nature communications 2014
Show all 3 references for 565536
Cow (Bovine) Polyclonal RLIM Primary Antibody for WB - ABIN2779479
Hiratani, Yamamoto, Mochizuki, Ohmori, Taira: Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions. in Development (Cambridge, England) 2003
missense mutation in RLIM gene was identified in four males with intellectual disability from a three-generation family.
RNF12 is a novel positive regulator of p53 (show TP53 Antibodies) pathway and an external E3 ubiquitin ligase (show MUL1 Antibodies) for MDM2 (show MDM2 Antibodies) destruction.
Rlim is a novel regulator of Stathmin (show STMN1 Antibodies) protein in a ubiquitin-dependent manner, and represents a new pathway for malignant phenotype turnover by modulating the level of Stathmin (show STMN1 Antibodies) protein in human osteosarcomas.
hus (show CFH Antibodies) regulated nucleocytoplasmic shuttling of RLIM/Rnf12 coordinates cellular compartments during mammary alveolar cell survival
TP53 (show TP53 Antibodies) does not directly bind to the RLIM promoter, it physically interacts with and prevents the binding of Sp1 (show PSG1 Antibodies) to the RLIM promoter.
these results indicated that RLIM is an important positive regulator in TGF-beta (show TGFB1 Antibodies) signaling pathway and cell migration.
RLIM represents a new pathway for telomere maintenance by modulating the level of TRF1 (show TERF1 Antibodies) at telomeres.
These findings provide evidence for a dose-dependent role of RNF12 in the XCI counting and initiation process.
In late preimplantation, Oct4 (show POU5F1 Antibodies) served as a chromatin opener to create transcriptional permissive states at Xm-Xist/Tsix genomic loci. In parthenogenetic embryos, Rnf12 overdose caused Xm-Xist derepression via Xm-Tsix repression; physiological Rnf12 levels were essential for Xm-Xist silencing maintenance in fertilized embryos.
high RNF12 levels may contribute to the specific activation of maternal Xist in XpDeltaXist female ROSI embryos, but upregulation of additional Xp derived factors and/or the specific epigenetic constitution of the round spermatid-derived Xp are expected to be more critical
results provide evidence that RLIM is dispensable for rXCI, indicating that in mice an RLIM-independent mechanism activates Xist in the embryo proper
The trans-activator RNF12 and cis (show CISH Antibodies)-acting elements effectuate X chromosome inactivation independent of X-pairing.
RNF12 causes REX1 (show REXO1 Antibodies) breakdown through dose-dependent catalysis, thereby representing an important pathway to initiate X-chromosome inactivation
Results provide strong evidence that RLIM/Rnf12 is required for the survival of differentiated milk-producing alveolar cells in pregnant and lactating female mice.
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.
RNF12 is essential for initiation of XCI and is mainly involved in the regulation of Xist.
results assign crucial functions to the maternal deposit of Rnf12/RLIM for the initiation of imprinted X-chromosome inactivation
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
E3 ubiquitin-protein ligase RLIM
, E3 ubiquitin-protein ligase RNF12
, LIM domain-interacting RING finger protein
, RING finger LIM domain-binding protein
, renal carcinoma antigen NY-REN-43
, ring finger protein 12
, ring zinc finger LIM domain binding protein
, ring zinc finger protein NY-REN-43antigen
, LIM domain interacting RING finger protein
, Hoxa1 regulated