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SH3-Domain GRB2-Like Endophilin B1 Proteins (SH3GLB1)

SH3GLB1 encodes a SRC homology 3 domain-containing protein. Additionally we are shipping SH3GLB1 Antibodies (123) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SH3GLB1 54673 Q9JK48
SH3GLB1 51100 Q9Y371
SH3GLB1 292156 Q6AYE2
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Top SH3GLB1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SH3GLB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced SH3GLB1 Proteins

  1. Human SH3GLB1 Protein expressed in Escherichia coli (E. coli) - ABIN1098454 : Modregger, Schmidt, Ritter, Huttner, Plomann: Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN1098454

More Proteins for SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) Interaction Partners

Mouse (Murine) SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) interaction partners

  1. these data reveal an Irgm1 (show IRGM Proteins)-dependent mechanism that promotes the tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy

  2. Our findings suggest that endophilin-B1 is a key mediator of a feed-forward mechanism of Alzheimer's disease pathogenesis

  3. selective autophagy regulates the basal and atrophy-induced turnover of the pentameric transmembrane protein, CHRN, and that TRIM63 (show TRIM63 Proteins), together with SH3GLB1 and SQSTM1 (show SQSTM1 Proteins) regulate this process.

  4. these data suggest that Bif-1 is essential for the maintenance of mitochondrial morphology and function in neurons

  5. Bif-1 haploinsufficiency attenuates mitophagy and results in the promotion of chromosomal instability, which enables tumor cells to efficiently bypass the oncogenic/metabolic pressures for apoptosis.

  6. findings not only establish Cdk5 (show CDK5 Proteins) as a critical regulator of autophagy induction, but also reveal a role for Cdk5 (show CDK5 Proteins) and EndoB1 in the pathophysiology of Parkinson's disease through modulating autophagy

  7. These findings suggest that Bif-1 acts as a critical regulator of Atg9 (show ATG9A Proteins) puncta formation presumably by mediating Golgi fission for autophagosome biogenesis during starvation.

  8. Bif-1 is an important component of the mitochondrial pathway for apoptosis as a novel Bax (show BAX Proteins)/Bak (show BAK1 Proteins) activator, and loss of this proapoptotic molecule may contribute to tumorigenesis.

  9. A potential role for endophilin B1t (show TUBB Proteins) in mammalian spermatogenesis is discussed within the context of the PP1c gamma knockout testis phenotype.

  10. Bif-1 interacts with Beclin 1 (show BECN1 Proteins) through ultraviolet irradiation resistance-associated gene (UVRAG (show UVRAG Proteins)) and functions as a positive mediator of the class III PI(3 (show PI3 Proteins)) kinase (PI(3 (show PI3 Proteins))KC3).

Human SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) interaction partners

  1. these data reveal an Irgm1 (show IRGM Proteins)-dependent mechanism that promotes the tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1 (show ZBTB24 Proteins)-dependent autophagy

  2. Our findings suggest that endophilin-B1 is a key mediator of a feed-forward mechanism of Alzheimer's disease pathogenesis

  3. Data suggest that activated autophagy is associated with the progression of pancreatic ductal adenocarcinoma and that the overexpression of autophagy-related proteins Atg5 (show ATG5 Proteins), Ambra1 (show AMBRA1 Proteins), beclin-1 (show BECN1 Proteins), LC3B (show MAP1LC3B Proteins) and Bif-1 (show ZBTB24 Proteins) is significantly correlated with poor outcome.

  4. these data suggest a novel function for Bif-1 (show ZBTB24 Proteins) as a suppressor of breast cancer cell migration by promoting EGFR (show EGFR Proteins) degradation through the regulation of endosome maturation

  5. The expression of Bif-1 (show ZBTB24 Proteins) is downregulated in a subset of pancreatic ductal adenocarcinoma. This novel finding is in agreement with the tumor suppressor function of Bif-1 (show ZBTB24 Proteins).

  6. These findings suggest that Bif-1 (show ZBTB24 Proteins) acts as a critical regulator of Atg9 (show ATG9A Proteins) puncta formation presumably by mediating Golgi fission for autophagosome biogenesis during starvation.

  7. GSK-3beta promotes cell survival by modulating Bif-1 (show ZBTB24 Proteins)-dependent autophagic response and cell death.

  8. Double knockdown of endophilin B1 and Drp1 (show CRMP1 Proteins) leads to a mitochondrial phenotype identical to that of the Drp1 (show CRMP1 Proteins) single knockdown, a result consistent with Drp1 (show CRMP1 Proteins) acting upstream of endophilin B1 in the maintenance of morphological dynamics of mitochondria.

  9. Bif-1 (show ZBTB24 Proteins) is an important component of the mitochondrial pathway for apoptosis as a novel Bax (show BAX Proteins)/Bak (show BAK1 Proteins) activator, and loss of this proapoptotic molecule may contribute to tumorigenesis.

  10. BAR domain of endophilin-A1 (show SH3G2 Proteins) drives membrane curvature by coordinate action of the crescent's scaffold mechanism and the ridge's membrane insertion in addition to membrane binding via amino-terminal amphipathic helix.

SH3GLB1 Protein Profile

Protein Summary

This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SH3GLB1

  • SH3-domain GRB2-like endophilin B1 (sh3glb1)
  • SH3-domain GRB2-like endophilin B1 (SH3GLB1)
  • zgc:110259 (zgc:110259)
  • SH3-domain GRB2-like endophilin B1 (LOC100227417)
  • SH3-domain GRB2-like B1 (endophilin) (Sh3glb1)
  • SH3-domain GRB2-like endophilin B1 (Sh3glb1)
  • AA409932 protein
  • AI314629 protein
  • AU015566 protein
  • Bif-1 protein
  • dJ612B15.2 protein
  • im:5777505 protein
  • MGC79086 protein
  • mKIAA0491 protein
  • PPP1R70 protein
  • sh3glb1 protein
  • wu:fa08f03 protein
  • wu:fb13e12 protein
  • wu:fc55h11 protein
  • wu:fj98d09 protein

Protein level used designations for SH3GLB1

SH3-domain GRB2-like endophilin B1 , endophilin-B1 , fc55h11 , fj98d09 , endophilin-B1-like , SH3 domain-containing GRB2-like protein B1 , Bax-interacting factor 1 , SH3-containing protein SH3GLB1 , protein phosphatase 1, regulatory subunit 70 , SH3-domain GRB2-like B1 (endophilin) , SH3 domain GRB2-like protein B1

GENE ID SPECIES
334911 Danio rerio
443857 Xenopus laevis
548826 Xenopus (Silurana) tropicalis
712393 Macaca mulatta
792229 Danio rerio
100009963 Monodelphis domestica
100227417 Taeniopygia guttata
100316852 Sus scrofa
100386778 Callithrix jacchus
54673 Mus musculus
51100 Homo sapiens
292156 Rattus norvegicus
612505 Canis lupus familiaris
533918 Bos taurus
424522 Gallus gallus
100173032 Pongo abelii
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