anti-Selectin P Ligand (SELPLG) Antibodies

SELPLG encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. Additionally we are shipping SELPLG Kits (29) and SELPLG Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SELPLG 12720  
SELPLG 6404 Q14242
SELPLG 363930  
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Top anti-SELPLG Antibodies at antibodies-online.com

Showing 10 out of 263 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated FACS, WB SELPLG Antibody (C-term)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). SELPLG Antibody (C-term)  flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse FITC FACS   1 mL Log in to see 6 to 8 Days
$253.00
Details
Human Rat Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (fro), IHC (p), WB Human peripheral blood lymphocytes stained with purified HECA-452, followed by anti-mouse IgG FITC Flow (Cell Surface): Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [ABIN2629479] - A cell surface stain was performed on CD14+ hPBMCs with Cutaneous Lymphocyte Antigen (CLA) antibody (HECA-452) ABIN2629479 and a matched isotype control NBP2-31379. Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature, followed by rat-Dylight 488 conjugated secondary antibody. A co-stain was performed using CD14 antibody ABIN2629478AF488. 0.1 mL Log in to see 7 to 9 Days
$357.00
Details
Human Rabbit Un-conjugated EIA, FACS, WB flow cytometric analysis of Jurkat cells using SELPLG Antibody (C-term) Cat.-No AP53840PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of SELPLG Antibody (C-term) Cat.-No AP53840PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB   0.2 mg Log in to see 6 to 8 Days
$632.50
Details
Human Mouse Un-conjugated Func, FACS   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse APC FACS Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2). 100 Tests Log in to see 5 to 7 Days
$334.95
Details

SELPLG Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SELPLG Antibodies

  1. Mouse (Murine) Monoclonal SELPLG Primary Antibody for BR, FACS - ABIN1177261 : Borges, Eytner, Moll, Steegmaier, Campbell, Ley, Mossmann, Vestweber: The P-selectin glycoprotein ligand-1 is important for recruitment of neutrophils into inflamed mouse peritoneum. in Blood 1997 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal SELPLG Primary Antibody for CyTOF, ELISA - ABIN262947 : Walcheck, Leppanen, Cummings, Knibbs, Stoolman, Alexander, Mattila, McEver: The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin. in Blood 2002 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal SELPLG Primary Antibody for Func, FACS - ABIN610433 : Connolly, Chait, Duncan, Taylor: CT-guided percutaneous needle biopsy of small lung nodules in children. in Pediatric radiology 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal SELPLG Primary Antibody for CyTOF, FACS - ABIN4348165 : Wake, Mori, Liu, Morioka, Teshigawara, Sakaguchi, Kuroda, Gao, Takahashi, Ohtsuka, Yoshino, Morimatsu, Nishibori: Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation. in EBioMedicine 2016 (PubMed)

  5. Human Monoclonal SELPLG Primary Antibody for BR, FACS - ABIN967490 : Snapp, Ding, Atkins, Warnke, Luscinskas, Kansas: A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin. in Blood 1998 (PubMed)

More Antibodies against SELPLG Interaction Partners

Mouse (Murine) Selectin P Ligand (SELPLG) interaction partners

  1. results indicate that P-selectin (show SELP Antibodies) deletion significantly decreases tumor stiffness in Rip1 (show RALBP1 Antibodies)-Tag2 mice by inhibiting LOX (show LOX Antibodies) expression.

  2. this study shows that PSGL-1 plays a fundamental role in balancing viral control and immunopathology and also functions to regulate T cell responses in the tumor microenvironment

  3. Psgl-1 deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (show AKT1 Antibodies) axis.

  4. Circulating soluble P-selectin (show SELP Antibodies) must dimerize to promote inflammation and thrombosis in mice.

  5. The results from the present study suggest that activated platelets secrete Pselectin to promote cardiac inflammation and fibrosis in Ang (show ANG Antibodies) IIinduced hypertension.

  6. These findings indicate a novel pathway in tumor metastasis, i.e., tumor cell mediated activation of P-selectin (show SELP Antibodies) in platelets, followed by activation and secretion of Asm (show SMPD1 Antibodies) and in turn release of ceramide and tumor metastasis. The data suggest that p38 MAPK (show MAPK14 Antibodies) acts downstream from P-selectin (show SELP Antibodies) and is necessary for the secretion of Asm (show SMPD1 Antibodies).

  7. Psgl-1 deficiency is protective against the prothrombotic effects of IL-1beta (show IL1B Antibodies) .

  8. PSGL-1, CD43, and CD44 moved normally to the uropods of chemokine-stimulated C1galt1(-/-) neutrophils

  9. these results demonstrate that P-selectin (show SELP Antibodies) expression on ECs is regulated in part by glycosylation mechanisms and that glycosylation inhibitors efficiently reduce the adhesion of sRBCs and leukocytes to ECs.

  10. endothelial colony-forming cells interact with (show SELL Antibodies)activated neutrophils via PSGL-1 and L-selectin

Human Selectin P Ligand (SELPLG) interaction partners

  1. Results suggest that PSGL-1 may play an oncogenic role in the development of intestinal tumors, and this is likely mediated through activation of NFkB signaling by MIP (show TNPO1 Antibodies)-1g.

  2. c-Myc (show MYC Antibodies) regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection.

  3. The percentage of CXCR3 (show CXCR3 Antibodies)(+) CD4 (show CD4 Antibodies)(+) TEM (show CYLD Antibodies) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA(+) CD4 (show CD4 Antibodies)(+) TCM cells expressing CCR6 (show CCR6 Antibodies)(+) or CCR4 (show CCR4 Antibodies)(+)CXCR3 (show CXCR3 Antibodies)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  4. Platelet-leukocyte aggregations increased in acute ischemic stroke patients rapidly within 3h. The I allele of PSGL-1 M62I was associated with risk of developing acute ischemic stroke, especially large artery atherosclerosis stroke and small artery occlusion stroke. Small artery occlusion stroke patients with the II genotype of PSGL-1 M62I have the higher level of platelet-neutrophil aggregates.

  5. The significant presence of CLA+ T cells and E-selectin (show SELE Antibodies) expressions in the OLPG suggests their involvement in the etiopathogenesis of OLP; however, only a weak correlation between CLA+ T cells and E-selectin (show SELE Antibodies) was observed.

  6. PSGL-1 is a novel receptor for S. pneumoniae that contributes to protection against invasive pneumococcal disease.

  7. This study provides a better understanding of the biology of P-selectin (show SELP Antibodies) and PSGL-1 and their roles in dissemination and resensitization of Multiple myeloma treatment.

  8. Report influence of SELPLG variation on leukocyte-platelet interactions in cardiovascular disease.

  9. E-selectin (show SELE Antibodies) interactions with glycoprotein ligands (CD44 (show CD44 Antibodies)/hematopoietic cell E-/L-selectin (show SELL Antibodies) ligand and PSGL-1) mediate the initial capturing of cells out of flow.

  10. CD162 staining and the staining degree, with the other standard immunohistochemical stains, were shown to be beneficial in the diagnosis of multiple myeloma disease.

SELPLG Antigen Profile

Protein Summary

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SELPLG

  • selectin P ligand (SELPLG) antibody
  • clasper (cla) antibody
  • selectin P ligand (Selplg) antibody
  • selectin, platelet (p-selectin) ligand (Selplg) antibody
  • synaptotagmin-like 1 (Sytl1) antibody
  • 9030417L18 antibody
  • CD162 antibody
  • CLA antibody
  • Psgl-1 antibody
  • Psgl1 antibody
  • Selp1 antibody
  • SELPG antibody
  • Selpl antibody
  • SELPLG antibody
  • Slp1 antibody

Protein level used designations for SELPLG

selectin P ligand , P-selectin glycoprotein ligand 1 , P-selectin glycoprotein ligand 1 propeptide , cutaneous lymphocyte-associated associated antigen , leukocyte cell surface adhesion molecule , selectin, platelet (p-selectin) ligand , P-selectin glycoprotein ligand-1 , exophilin-7 , synaptotagmin-like protein 1

GENE ID SPECIES
452211 Pan troglodytes
611673 Canis lupus familiaris
617434 Bos taurus
100034025 Equus caballus
100125963 Sus scrofa
12720 Mus musculus
6404 Homo sapiens
363930 Rattus norvegicus
20345 Mus musculus
269589 Mus musculus
Selected quality suppliers for anti-SELPLG (SELPLG) Antibodies
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